Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aya M. El-Seidy"'
Autor:
Sherry N. Nasralla, Tamer M. Ibrahim, Ahmed M. M. Hassan, Alaa El-Din A. Bekhit, Manal N. S. Saudi, Aya M. El-Seidy, Salwa M. Fahmy, Adnan A. Bekhit, Doaa A. Ghareeb
Publikováno v:
European journal of medicinal chemistry. 163
New 1,3,4-trisubstituted pyrazole derivatives were synthesized and evaluated for their antiplasmodial activity. Compounds 4b, 4c, 7a and 7d were the most potent antiplasmodial agents against P. berghei with percent of suppression ranging from 90 to 1
Autor:
Huda J Habib, Salwa M. Fahmy, Manal N. S. Saudi, Alaa El-Din A. Bekhit, Adnan A. Bekhit, Aya M. El-Seidy, Sayed Mahmood Alqallaf, Tamer M. Ibrahim, Doaa A. Ghareeb, Ahmed Mm Hassan
Publikováno v:
Future medicinal chemistry. 10(19)
Aim: Novel open chain and cyclized derivatives containing pyrazole scaffold were designed, synthesized and evaluated as antileishmanial compounds. Methodology & results: In silico reverse docking experiment suggested Leishmania major pteridine reduct