EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa

Autor: Biraj B. Kayastha, Aya Kubo, Jacob Burch-Konda, Rosalie L. Dohmen, Jacee L. McCoy, Rendi R. Rogers, Sergio Mares, Justin Bevere, Annalisa Huckaby, William Witt, Shuxia Peng, Bharat Chaudhary, Smita Mohanty, Mariette Barbier, Gabriel Cook, Junpeng Deng, Marianna A. Patrauchan

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Calcium (Ca2+) is well known as a second messenger in eukaryotes, where Ca2+ signaling controls life-sustaining cellular processes. Although bacteria produce the components required for Ca2+ signaling, little is known about the mechanisms of

Externí odkaz: https://doaj.org/article/25b2537cac2b4b44875de3dcda394a67

Complete Genome Sequence of the Radioresistant Bacterium Deinococcus aetherius ST0316, Isolated from Air Dust Collected in the Lower Stratosphere above Japan

Autor: Katsuya Satoh, Kakeru Hagiwara, Kosuke Katsumata, Aya Kubo, Shin-ichi Yokobori, Akihiko Yamagishi, Yutaka Oono, Issay Narumi

Publikováno v: Microbiology resource announcements. 11(10)

Deinococcus aetherius ST0316 is a radioresistant bacterium that possess proficient DNA repair capacity. Here, we report the complete genome sequence of D. aetherius , which was obtained by hybrid assembly using short- and long-read sequencing. This s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d473669f7aa2af12cd568e74bc09b24f
https://pubmed.ncbi.nlm.nih.gov/36106892

Calcium-Regulated Protein CarP Responds to Multiple Host Signals and Mediates Regulation of Pseudomonas aeruginosa Virulence by Calcium

Autor: Tyrrell Conway, Daniel McLeod, Aya Kubo, Reygan E. Braga, Sharmily Khanam, Leah Kafer, Marianna A. Patrauchan, Michelle King

Publikováno v: Appl Environ Microbiol

Pseudomonas aeruginosa is an opportunistic pathogen causing life-threatening infections. Previously, we showed that elevated calcium (Ca(2+)) levels increase the production of virulence factors in P. aeruginosa. In an effort to characterize the Ca(2+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f4c02b8ee45ba730b93cf016e60477
https://pubmed.ncbi.nlm.nih.gov/33674436

XRISM Spectroscopy of the Fe Kα Emission Line in the Seyfert Active Galactic Nucleus NGC 4151 Reveals the Disk, Broad-line Region, and Torus

Autor: XRISM Collaboration, Marc Audard, Hisamitsu Awaki, Ralf Ballhausen, Aya Bamba, Ehud Behar, Rozenn Boissay-Malaquin, Laura Brenneman, Gregory V. Brown, Lia Corrales, Elisa Costantini, Renata Cumbee, Maria Diaz Trigo, Chris Done, Tadayasu Dotani, Ken Ebisawa, Megan E. Eckart, Dominique Eckert, Teruaki Enoto, Satoshi Eguchi, Yuichiro Ezoe, Adam Foster, Ryuichi Fujimoto, Yutaka Fujita, Yasushi Fukazawa, Kotaro Fukushima, Akihiro Furuzawa, Luigi Gallo, Javier A. García, Liyi Gu, Matteo Guainazzi, Kouichi Hagino, Kenji Hamaguchi, Isamu Hatsukade, Katsuhiro Hayashi, Takayuki Hayashi, Natalie Hell, Edmund Hodges-Kluck, Ann Hornschemeier, Yuto Ichinohe, Manabu Ishida, Kumi Ishikawa, Yoshitaka Ishisaki, Jelle Kaastra, Timothy Kallman, Erin Kara, Satoru Katsuda, Yoshiaki Kanemaru, Richard Kelley, Caroline Kilbourne, Shunji Kitamoto, Shogo Kobayashi, Takayoshi Kohmura, Aya Kubota, Maurice Leutenegger, Michael Loewenstein, Yoshitomo Maeda, Maxim Markevitch, Hironori Matsumoto, Kyoko Matsushita, Dan McCammon, Brian McNamara, François Mernier, Eric D. Miller, Jon M. Miller, Ikuyuki Mitsuishi, Misaki Mizumoto, Tsunefumi Mizuno, Koji Mori, Koji Mukai, Hiroshi Murakami, Richard Mushotzky, Hiroshi Nakajima, Kazuhiro Nakazawa, Jan-Uwe Ness, Kumiko Nobukawa, Masayoshi Nobukawa, Hirofumi Noda, Hirokazu Odaka, Shoji Ogawa, Anna Ogorzalek, Takashi Okajima, Naomi Ota, Stephane Paltani, Robert Petre, Paul Plucinsky, Frederick S. Porter, Katja Pottschmidt, Kosuke Sato, Toshiki Sato, Makoto Sawada, Hiromi Seta, Megumi Shidatsu, Aurora Simionescu, Randall Smith, Hiromasa Suzuki, Andrew Szymkowiak, Hiromitsu Takahashi, Mai Takeo, Toru Tamagawa, Keisuke Tamura, Takaaki Tanaka, Atsushi Tanimoto, Makoto Tashiro, Yukikatsu Terada, Yuichi Terashima, Yohko Tsuboi, Masahiro Tsujimoto, Hiroshi Tsunemi, Takeshi Tsuru, Hiroyuki Uchida, Nagomi Uchida, Yuusuke Uchida, Hideki Uchiyama, Yoshihiro Ueda, Shinichiro Uno, Jacco Vink, Shin Watanabe, Brian J. Williams, Satoshi Yamada, Shinya Yamada, Hiroya Yamaguchi, Kazutaka Yamaoka, Noriko Yamasaki, Makoto Yamauchi, Shigeo Yamauchi, Tahir Yaqoob, Tomokage Yoneyama, Tessei Yoshida, Mihoko Yukita, Irina Zhuravleva, Xin Xiang, Takeo Minezaki, Margaret Buhariwalla, Dimitra Gerolymatou, Scott Hagen

Publikováno v: The Astrophysical Journal Letters, Vol 973, Iss 1, p L25 (2024)

We present an analysis of the first two XRISM/Resolve spectra of the well-known Seyfert-1.5 active galactic nucleus (AGN) in NGC 4151, obtained in 2023 December. Our work focuses on the nature of the narrow Fe K _α emission line at 6.4 keV, the stro

Externí odkaz: https://doaj.org/article/5d83f682f7f5495191f4acac34927e55

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases

Autor: Ron Caspi, Tomer Altman, Richard Billington, Kate Dreher, Hartmut Foerster, Carol A. Fulcher, Timothy A. Holland, Ingrid M. Keseler, Anamika Kothari, Aya Kubo, Markus Krummenacker, Mario Latendresse, Lukas A. Mueller, Quang Ong, Suzanne Paley, Pallavi Subhraveti, Daniel S. Weaver, Deepika Weerasinghe, Peifen Zhang, Peter D. Karp

Publikováno v: Nucleic Acids Research

The MetaCyc database (MetaCyc.org) is a comprehensive and freely accessible database describing metabolic pathways and enzymes from all domains of life. MetaCyc pathways are experimentally determined, mostly small-molecule metabolic pathways and are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d93c151fa4d274bcebe9f2ec26f864
http://europepmc.org/articles/PMC3964957