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pro vyhledávání: '"Aya Hongo"'
Publikováno v:
Analytical Biochemistry. 557:77-83
With the development of various methods for affinity-based selection of proteins such as phage display, ribosomal display, and mRNA display, the progress in this field has been gradually shifting to function-based selection, such as through single-mo
Autor:
Himari Ogino, Tomomi Miyamoto, Takana Kamei, Aya Hongo, Takao Kohno, Takumi Ishizuka, Hitomi Tsuiji, Mitsuharu Hattori, Keisuke Ishii, Hisashi Oishi, Yuko Yamakage, Michinao Kato
Publikováno v:
Molecular and Cellular Neuroscience. 100:103401
Reelin plays important roles in regulating neuronal development, modulating synaptic function, and counteracting amyloid β toxicity. A specific proteolytic cleavage (N-t cleavage) of Reelin abolishes its biological activity. We recently identified A
Publikováno v:
Analytical Biochemistry. 480:82-84
O(6)-Methylguanine DNA methyltransferase (MGMT) cancels the anticancer effect of temozolomide (drug for glioblastoma), which introduces methylation to DNA. Therefore, developing an MGMT inhibitor is a promising strategy for the treatment of this canc
Publikováno v:
Seibutsu Butsuri. 54:S262