Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aya Hefnawy"'
Autor:
Aya Hefnawy, Gabriel Negreira, Marlene Jara, James A. Cotton, Ilse Maes, Erika D’Haenens, Hideo Imamura, Bart Cuypers, Pieter Monsieurs, Christina Mouchtoglou, Hans De Winter, Isabel Pintelon, Jean-Pierre Timmermans, Matt Berriman, Mandy Sanders, Julio Martin, Geraldine de Muylder, Jean-Claude Dujardin, Yann G.-J. Sterckx, Malgorzata Anna Domagalska
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The implementation of prospective drug resistance (DR) studies in the research-and-development (R&D) pipeline is a common practice for many infectious diseases but not for neglected tropical diseases (NTDs). Here, we explored and demonstrate
Externí odkaz:
https://doaj.org/article/e80a58f28d3e4a0b837c97b9b12a4bca
Autor:
Matthew Berriman, Ilse Maes, Malgorzata A. Domagalska, Jeffrey N. Martin, Hideo Imamura, Mandy Sanders, Erika D’Haenens, Pieter Monsieurs, Jean-Claude Dujardin, Yann G.-J. Sterckx, G. De Muylder, James Cotton, Negreira Gh, Marlene Jara, H. De Winter, C. Mouchtoglou, Bart Cuypers, Aya Hefnawy
The implementation of prospective drug resistance (DR) studies in the R&D pipelines is a common practice for many infectious diseases, but not for Neglected Tropical Diseases. Here, we explored and demonstrated the importance of this approach, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaeffa7bf4e9a1cdf1d2ac95d768c979
https://doi.org/10.1101/2021.01.05.425522
https://doi.org/10.1101/2021.01.05.425522
Autor:
Juan Cantizani, Suman Rijal, Aya Hefnawy, Pilar Manzano, Géraldine De Muylder, Jean-Claude Dujardin, Julio Martin, Imanol Peña
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific reports
The growing drug resistance (DR) raises major concerns for the control of visceral leishmaniasis (VL), a neglected disease lethal in 95 percent of the cases if left untreated. Resistance has rendered antimonials (SSG) obsolete in the Indian Sub-Conti
Publikováno v:
Trends in Parasitology
New drugs are needed to control leishmaniasis and efforts are currently on-going to counter the neglect of this disease. We discuss here the utility and the impact of associating drug resistance (DR) studies to drug discovery pipelines. We use as par