MTA1, a Novel ATP Synthase Complex Modulator, Enhances Colon Cancer Liver Metastasis by Driving Mitochondrial Metabolism Reprogramming

Autor: Ting Wang, Fangzhou Sun, Chunxiao Li, Peng Nan, Yan Song, Xuhao Wan, Hongnan Mo, Jinsong Wang, Yantong Zhou, Yuzheng Guo, Aya Ei Helali, Dongkui Xu, Qimin Zhan, Fei Ma, Haili Qian

Publikováno v: Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)

Abstract Liver metastasis is the most fatal event of colon cancer patients. Warburg effect has been long challenged by the fact of upregulated oxidative phosphorylation (OXPHOS), while its mechanism remains unclear. Here, metastasis‐associated anti

Externí odkaz: https://doaj.org/article/bdf2ecd8f92847e89863a5ed9dd51dd1

MTA1, a Novel ATP Synthase Complex Modulator, Enhances Colon Cancer Liver Metastasis by Driving Mitochondrial Metabolism Reprogramming.

Autor: Wang, Ting^1,2 (AUTHOR), Sun, Fangzhou² (AUTHOR), Li, Chunxiao^2,3 (AUTHOR), Nan, Peng⁴ (AUTHOR), Song, Yan⁵ (AUTHOR), Wan, Xuhao⁶ (AUTHOR), Mo, Hongnan³ (AUTHOR), Wang, Jinsong² (AUTHOR), Zhou, Yantong² (AUTHOR), Guo, Yuzheng⁶ (AUTHOR), Helali, Aya Ei⁷ (AUTHOR), Xu, Dongkui⁸ (AUTHOR) xudongkui@cicams.ac.cn, Zhan, Qimin^1,9,10,11 (AUTHOR) zhanqimin@bjmu.edu.cn, Ma, Fei^3,12 (AUTHOR) mafei@cicams.ac.cn, Qian, Haili² (AUTHOR) qianhaili@pumc.edu.cn

Publikováno v: Advanced Science. 9/5/2023, Vol. 10 Issue 25, p1-16. 16p.