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Akademický článek

In silico and cheminformatics prediction with experimental validation of an adipogenesis cocktail, sorafenib with rosiglitazone for HCC dedifferentiation

Autor: Aya Anis, Ahmed M. Mostafa, Mariam S. Kerema, Nadia M. Hamdy, Ahmed S. Sultan

Publikováno v: Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 4, Pp 100429- (2024)

Purpose: Hepatocellular carcinoma (HCC) resistance to sorafenib treatment and other treatment strategies causes a higher mortality rate in patients diagnosed with HCC.Research question.HCC often develops resistance to sorafenib treatment and other th

Externí odkaz: https://doaj.org/article/d3d387d2e4c046f99d2b1e8ceebda931

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Abstract 1596: The promising recipe sorafenib rosiglitazone and adipogenesis inducers cocktail for in vitro hepatocellular carcinoma differentiation induction besiege carcinogenesis

Autor: Aya Anis, Ahmed M. Mostafa, Nadia M. Hamdy, Ahmed S. Sultan

Publikováno v: Cancer Research. 83:1596-1596

Aim: The present study is focusing on using sorafenib, rosiglitazone, and adipogenesis-inducers cocktail (Insulin, Dexamethasone and IBMX) as a combination treatment to induce hepatocellular carcinoma (HCC) cell lines differentiation into adipocyte f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f33c3800d0a03cd00f8da7426c7998e3
https://doi.org/10.1158/1538-7445.am2023-1596

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