Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aya, Zeghimi"'
Autor:
Jean-Michel Escoffre, Patrick Vourc'h, Aya Zeghimi, Rose-Anne Thépault, Ayache Bouakaz, Anthony Novell
Publikováno v:
Journal of Drug Targeting
Journal of Drug Targeting, Informa Healthcare, 2014, 22 (8), pp.748-760. ⟨10.3109/1061186X.2014.921922⟩
Journal of Drug Targeting, Informa Healthcare, 2014, 22 (8), pp.748-760. ⟨10.3109/1061186X.2014.921922⟩
Plasmid DNA (pDNA) is attractive molecule for gene therapy. pDNA-targeted delivery by efficient and safe methods is required to enhance its intra-tissue bioavailability. Among non-viral methods, sonoporation has become a promising method for in-vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaf765f06644cc5c22a041a3c34f2fa
https://doi.org/10.3109/1061186x.2014.921922
https://doi.org/10.3109/1061186x.2014.921922
Publikováno v:
AIP Conference Proceedings.
BackgroundSonoporation promises a local gene/drug delivery with a high therapeutic efficacy and low toxicity level. However, the mechanisms orchestrating the molecules uptake are still unclear. Here, we investigate the effects of sonoporation on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c3e0c3ebd3fe4abc3fc1db0a5a5e5d
https://doi.org/10.1063/1.4977635
https://doi.org/10.1063/1.4977635
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319225357
Contrast agents for ultrasound are now routinely used for diagnosis and imaging. In recent years, new promising possibilities for targeted drug delivery have been proposed that can be realized by using the microbubble composing ultrasound contrast ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e13a696e3284b26671d81a43537fe42
https://doi.org/10.1007/978-3-319-22536-4_10
https://doi.org/10.1007/978-3-319-22536-4_10
Publikováno v:
Physical Biology
Physical Biology, Institute of Physics: Hybrid Open Access, 2015, 12 (6), pp.066007. ⟨10.1088/1478-3975/12/6/066007⟩
Physical Biology, 2015, 12 (6), pp.066007. ⟨10.1088/1478-3975/12/6/066007⟩
Physical Biology, Institute of Physics: Hybrid Open Access, 2015, 12 (6), pp.066007. ⟨10.1088/1478-3975/12/6/066007⟩
Physical Biology, 2015, 12 (6), pp.066007. ⟨10.1088/1478-3975/12/6/066007⟩
A Zeghimi and JM Escoffre have contributed equally to this work.; International audience; Sonoporation is a physical method that has been successfully used to deliver drugs into living cells both in vitro and in vivo for experimental and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c3743487d13e59cd8b87c4b0525bb3
https://pubmed.ncbi.nlm.nih.gov/26599283
https://pubmed.ncbi.nlm.nih.gov/26599283
Publikováno v:
Advances in experimental medicine and biology. 880
Contrast agents for ultrasound are now routinely used for diagnosis and imaging. In recent years, new promising possibilities for targeted drug delivery have been proposed that can be realized by using the microbubble composing ultrasound contrast ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ea409a4fee92b86a6d11f7852029fb5
https://pubmed.ncbi.nlm.nih.gov/26486338
https://pubmed.ncbi.nlm.nih.gov/26486338
Publikováno v:
2014 IEEE International Ultrasonics Symposium.
The mechanisms by which sonoporation increases the native plasma membrane permeability are still unknown but various hypotheses have been suggested including pore formation and endocytosis. We have shown recently that caveolae-mediated endocytosis pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf5ac6d23bd2b4ee40972d67766b670
https://doi.org/10.1109/ultsym.2014.0209
https://doi.org/10.1109/ultsym.2014.0209
Publikováno v:
2013 IEEE International Ultrasonics Symposium (IUS).
Sonoporation increases transiently the cell membrane permeability, enabling the therapeutic compounds internalization into the cells. Several investigations reported heterogeneities in the permeabilization and transfection efficacy depending on the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b4ca6cadbb7fd60207917ee9b5ae078
https://doi.org/10.1109/ultsym.2013.0016
https://doi.org/10.1109/ultsym.2013.0016
Publikováno v:
Current Gene Therapy
Current Gene Therapy, Bentham Science Publishers, 2013, 13 (1), pp.2-14. ⟨10.2174/156652313804806606⟩
Current Gene Therapy, Bentham Science Publishers, 2013, 13 (1), pp.2-14. ⟨10.2174/156652313804806606⟩
The increasing knowledge of cellular and molecular mechanisms of human diseases allows envisaging the gene therapy by sonoporation as an emerging and promising therapeutic alternative. Sonoporation combines the local application of ultrasound waves a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bdb67086c5dd4fd4219e9d3d0fa2f7
https://www.hal.inserm.fr/inserm-02438876
https://www.hal.inserm.fr/inserm-02438876
Autor:
Jean-Michel Escoffre, Alexander A. Doinikov, J. Piron, Aya Zeghimi, Anthony Novell, Ayache Bouakaz
Publikováno v:
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers, 2013, 60 (1), ⟨10.1109/TUFFC.2013.2536⟩
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers, 2013, 60 (1), ⟨10.1109/TUFFC.2013.2536⟩
This technical note investigates the involvement of microbubble attenuation and destruction in sonoporation mechanisms. First, we evaluate sonoporation efficiency using Vevo Micromarker, and a comparison is made with BR14 and SonoVue microbubbles. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f531757f33ef1805eb60e063351044
https://www.hal.inserm.fr/inserm-02438857
https://www.hal.inserm.fr/inserm-02438857