Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer

Autor: Lee, Soojung, Toft, Nicolai Juel, Axelsen, Trine Veje, Espejo, Maria Sofia, Pedersen, Tina Myhre, Mele, Marco, Pedersen, Helene Lintrup, Balling, Eva, Johansen, Tonje, Burton, Mark, Thomassen, Mads, Vahl, Pernille, Christiansen, Peer Michael, Boedtkjer, Ebbe

Publikováno v: Lee, S, Toft, N J, Axelsen, T V, Espejo, M S, Pedersen, T M, Mele, M, Pedersen, H L, Balling, E, Johansen, T, Burton, M, Thomassen, M, Vahl, P, Christiansen, P M & Boedtkjer, E 2023, ' Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer ', Breast Cancer Research, vol. 25, 46 . https://doi.org/10.1186/s13058-023-01644-1

Background Carbonic anhydrases catalyze CO2/HCO3– buffer reactions with implications for effective H+ mobility, pH dynamics, and cellular acid–base sensing. Yet, the integrated consequences of carbonic anhydrases for cancer and stromal cell funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbae1ffcaa764a161bf66160eeb6939
https://doi.org/10.1186/s13058-023-01644-1

Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

Autor: Lee, Soojung, Axelsen, Trine Veje, Jessen, Nicolai, Pedersen, Stine Falsig, Vahl, Pernille, Boedtkjer, Ebbe

Publikováno v: Lee, S, Axelsen, T V, Jessen, N, Pedersen, S F, Vahl, P & Boedtkjer, E 2018, ' Na +,HCO 3 –-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice ' Oncogene, vol. 37, pp. 5569-5584 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::18c45264f72e2f167df377e022502ef2
https://pure.au.dk/portal/da/publications/nahco3cotransporter-nbcn1-slc4a7-accelerates-erbb2induced-breast-cancer-development-and-tumor-growth-in-mice(2e1e07a1-72e0-407f-b57e-9449c147d46e).html

Immunological investigations of Alzheimer's disease

Autor: Axelsen, Trine Veje

Publikováno v: Axelsen, T V 2011, Immunological investigations of Alzheimer's disease . Århus Universitet .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::cc0882b19f3c0c7c46af8a0a1e88e945
https://pure.au.dk/portal/da/publications/immunological-investigations-of-alzheimers-disease(9a3b6320-e904-4e73-9966-5f5d1e73c09a).html

Specific recognition of the C-terminal end of Aβ⁴² by a high affinity monoclonal antibody

Autor: Axelsen, Trine Veje^1,2 trine@loke.dk, Holm, Arne² loke@loke.dk, Birkelund, Svend², Christiansen, Gunna², Ploug, Michael³ m-ploug@finsenlab.dk, Holm, Ida Elisabeth⁴ idaholm@dadlnet.dk

Publikováno v: Molecular Immunology. Jul2009, Vol. 46 Issue 11/12, p2267-2273. 7p.