Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Axelle Cooreman"'
Autor:
Anne Caufriez, Andrés Tabernilla, Raf Van Campenhout, Axelle Cooreman, Kaat Leroy, Julen Sanz Serrano, Prashant Kadam, Bruna dos Santos Rodrigues, Arthur Lamouroux, Steven Ballet, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5664 (2022)
Although many efforts have been made to elucidate the pathogenesis of COVID-19, the underlying mechanisms are yet to be fully uncovered. However, it is known that a dysfunctional immune response and the accompanying uncontrollable inflammation lead t
Externí odkaz:
https://doaj.org/article/f18b8ed8708a4ef49d10d418fdc498df
Autor:
Axelle Cooreman, Anne Caufriez, Andrés Tabernilla, Raf Van Campenhout, Kaat Leroy, Prashant Kadam, Julen Sanz Serrano, Bruna dos Santos Rodrigues, Pieter Annaert, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5018 (2022)
Connexin43 (Cx43) hemichannels form a pathway for cellular communication between the cell and its extracellular environment. Under pathological conditions, Cx43 hemichannels release adenosine triphosphate (ATP), which triggers inflammation. Over the
Externí odkaz:
https://doaj.org/article/7484b767e99a430587de82277d54da2f
Autor:
Kaat Leroy, Cícero Júlio Silva Costa, Alanah Pieters, Bruna dos Santos Rodrigues, Raf Van Campenhout, Axelle Cooreman, Andrés Tabernilla, Bruno Cogliati, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12187 (2021)
Liver cancer cell lines are frequently used in vitro tools to test candidate anti-cancer agents as well as to elucidate mechanisms of liver carcinogenesis. Among such mechanisms is cellular communication mediated by connexin-based gap junctions. The
Externí odkaz:
https://doaj.org/article/23ea5ce4b700442b83ea081ef8558eb3
Autor:
Kaat Leroy, Alanah Pieters, Axelle Cooreman, Raf Van Campenhout, Bruno Cogliati, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11724 (2021)
Connexin-based channels play key roles in cellular communication and can be affected by deleterious chemicals. In this study, the effects of various genotoxic carcinogenic compounds, non-genotoxic carcinogenic compounds and non-carcinogenic compounds
Externí odkaz:
https://doaj.org/article/3b4681c2e07e4da8bba08f8e6243ce5a
Autor:
Andrés Tabernilla, Bruna dos Santos Rodrigues, Alanah Pieters, Anne Caufriez, Kaat Leroy, Raf Van Campenhout, Axelle Cooreman, Ana Rita Gomes, Emma Arnesdotter, Eva Gijbels, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 5038 (2021)
The liver is among the most frequently targeted organs by noxious chemicals of diverse nature. Liver toxicity testing using laboratory animals not only raises serious ethical questions, but is also rather poorly predictive of human safety towards che
Externí odkaz:
https://doaj.org/article/1aed975168d8453783ffe9163bc9d39e
Autor:
Axelle Cooreman, Raf Van Campenhout, Sara Crespo Yanguas, Eva Gijbels, Kaat Leroy, Alanah Pieters, Andrés Tabernilla, Pieter Van Brantegem, Pieter Annaert, Bruno Cogliati, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6534 (2020)
Connexins are goal keepers of tissue homeostasis, including in the liver. As a result, they are frequently involved in disease. The current study was set up to investigate the effects of cholestatic disease on the production of connexin26, connexin32
Externí odkaz:
https://doaj.org/article/033a81fe174e47309097ba3fa8e700e9
Autor:
Raf Van Campenhout, Sara Crespo Yanguas, Axelle Cooreman, Eva Gijbels, Kaat Leroy, Vânia Vilas-Boas, Nick Devoogdt, Serge Muyldermans, Bruno Cogliati, Mathieu Vinken
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 636 (2019)
Adherens junctions, consisting of cadherins and catenins, are a group of cell-to-cell junctions that mediate mechanistic linkage between neighboring cells. By doing so, adherens junctions ensure direct intercellular contact and play an indispensable
Externí odkaz:
https://doaj.org/article/88ae591e2add46a080b8187e9b490098
Autor:
Raf Van Campenhout, Kaat Leroy, Axelle Cooreman, Andrés Tabernilla, Bruno Cogliati, Prashant Kadam, Mathieu Vinken
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Connexin proteins oligomerize in hexameric structures called connexin hemichannels, which then dock to form gap junctions. Gap junctions direct cell-cell communication by allowing the exchange of small molecules and ions between neighboring cells. In
Autor:
Axelle Cooreman, Mathieu Vinken, Raf Van Campenhout, Kaat Leroy, Andrés Tabernilla, Bruno Cogliati, Alanah Pieters
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gap junctions in liver, as in other organs, play a critical role in tissue homeostasis. Inherently, these cellular constituents are major targets for systemic toxicity and diseases, including cancer. This review provides an overview of chemicals that
Autor:
Mathieu Vinken, Pieter Annaert, Sagnik Chatterjee, Axelle Cooreman, Lysiane Richert, Pieter Van Brantegem, Erwin Dreesen, Neel Deferm, Marlies Oorts
Bosentan, a well–known cholestatic agent, was not identified as cholestatic at concentrations up to 200 µM based on the drug-induced cholestasis (DIC) index value, determined in a sandwich-cultured human hepatocyte (SCHH)–based DIC assay. To obt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c217992b234cbd7bc6a7d4f08e3d953b
https://hdl.handle.net/20.500.14017/e05ae3dd-cdd5-4a09-8f8a-4cf98ecbca80
https://hdl.handle.net/20.500.14017/e05ae3dd-cdd5-4a09-8f8a-4cf98ecbca80