Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Axel Touchard"'
Autor:
Axel Touchard, Valentine Barassé, Jean-Michel Malgouyre, Michel Treilhou, Christophe Klopp, Elsa Bonnafé
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Venoms have evolved independently over a hundred times in the animal kingdom to deter predators and/or subdue prey. Venoms are cocktails of various secreted toxins, whose origin and diversification provide an appealing system for
Externí odkaz:
https://doaj.org/article/88f43f2758e74930b80bf529c2d52dce
Autor:
Samuel D. Robinson, Jennifer R. Deuis, Axel Touchard, Angelo Keramidas, Alexander Mueller, Christina I. Schroeder, Valentine Barassé, Andrew A. Walker, Nina Brinkwirth, Sina Jami, Elsa Bonnafé, Michel Treilhou, Eivind A. B. Undheim, Justin O. Schmidt, Glenn F. King, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Stings of certain ant species (Hymenoptera: Formicidae) can cause intense, long-lasting nociception. Here we show that the major contributors to these symptoms are venom peptides that modulate the activity of voltage-gated sodium (NaV) chann
Externí odkaz:
https://doaj.org/article/06020d0862264dda9a11dae6073fc211
Autor:
Steven Ascoët, Axel Touchard, Nathan Téné, Benjamin Lefranc, Jérôme Leprince, Françoise Paquet, Laurence Jouvensal, Valentine Barassé, Michel Treilhou, Arnaud Billet, Elsa Bonnafé
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106157- (2023)
Summary: Hymenopterans represent one of the most abundant groups of venomous organisms but remain little explored due to the difficult access to their venom. The development of proteo-transcriptomic allowed us to explore diversity of their toxins off
Externí odkaz:
https://doaj.org/article/400fe46900c24f249f62f4bf7f50d71c
Autor:
Valentine Barassé, Laurence Jouvensal, Guillaume Boy, Arnaud Billet, Steven Ascoët, Benjamin Lefranc, Jérôme Leprince, Alain Dejean, Virginie Lacotte, Isabelle Rahioui, Catherine Sivignon, Karen Gaget, Mélanie Ribeiro Lopes, Federica Calevro, Pedro Da Silva, Karine Loth, Françoise Paquet, Michel Treilhou, Elsa Bonnafé, Axel Touchard
Publikováno v:
Toxins, Vol 15, Iss 10, p 600 (2023)
Ants are among the most abundant terrestrial invertebrate predators on Earth. To overwhelm their prey, they employ several remarkable behavioral, physiological, and biochemical innovations, including an effective paralytic venom. Ant venoms are thus
Externí odkaz:
https://doaj.org/article/4970959d64c84ea59a29b67bf5faa112
Autor:
Samira R. Aili, Axel Touchard, Regan Hayward, Samuel D. Robinson, Sandy S. Pineda, Hadrien Lalagüe, Mrinalini, Irina Vetter, Eivind A. B. Undheim, R. Manjunatha Kini, Pierre Escoubas, Matthew P. Padula, Garry S. A. Myers, Graham M. Nicholson
Publikováno v:
Toxins, Vol 12, Iss 5, p 324 (2020)
A critical hurdle in ant venom proteomic investigations is the lack of databases to comprehensively and specifically identify the sequence and function of venom proteins and peptides. To resolve this, we used venom gland transcriptomics to generate a
Externí odkaz:
https://doaj.org/article/55d7d69d39f74058b7a192f9f196b696
Autor:
Jesus Guzman, Nathan Téné, Axel Touchard, Denis Castillo, Haouaria Belkhelfa, Laila Haddioui-Hbabi, Michel Treilhou, Michel Sauvain
Publikováno v:
Toxins, Vol 10, Iss 1, p 21 (2017)
The venom peptide bicarinalin, previously isolated from the ant Tetramorium bicarinatum, is an antimicrobial agent with a broad spectrum of activity. In this study, we investigate the potential of bicarinalin as a novel agent against Helicobacter pyl
Externí odkaz:
https://doaj.org/article/ad450864f4cc4ad29a80267d7f2f0ce6
Autor:
Axel Touchard, Samira R. Aili, Eduardo Gonçalves Paterson Fox, Pierre Escoubas, Jérôme Orivel, Graham M. Nicholson, Alain Dejean
Publikováno v:
Toxins, Vol 8, Iss 1, p 30 (2016)
Ants (Formicidae) represent a taxonomically diverse group of hymenopterans with over 13,000 extant species, the majority of which inject or spray secretions from a venom gland. The evolutionary success of ants is mostly due to their unique eusocialit
Externí odkaz:
https://doaj.org/article/46d916cb69c04b778f827309a5a10ad0
Autor:
Samira R. Aili, Matthew P. Padula, Alvaro Garcia, Axel Touchard, Christopher Murphy, Evelyne Deplazes, Graham M. Nicholson, Bruce Cornell, Upeksha Mirissa Lankage, Charles G. Cranfield
Publikováno v:
ACS Biomaterials Science and Engineering
ACS Biomaterials Science and Engineering, ACS, 2020, 6 (8), pp.4714-4721. ⟨10.1021/acsbiomaterials.0c00632⟩
ACS Biomaterials Science and Engineering, ACS, 2020, 6 (8), pp.4714-4721. ⟨10.1021/acsbiomaterials.0c00632⟩
International audience; Phospholipase-A (PLA) enzymes catalyze the hydrolysis of ester bonds in select glycerophospholipids. Sensors for rapidly measuring the PLA activity in biological samples have relevance in the study of venom compositions and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4c9114be61f3c0b971949ec00af834
https://doi.org/10.1021/acsbiomaterials.0c00632
https://doi.org/10.1021/acsbiomaterials.0c00632
Autor:
Samira R. Aili, Elsa Bonnafé, Benjamin Lefranc, Graham M. Nicholson, Axel Touchard, Valentine Barassé, Mrinalini, Laurent Coquet, Alain Dejean, R. Manjunatha Kini, Thierry Jouenne, Pierre Escoubas, Michel Treilhou, Christophe Klopp, Nathan Téné, Jérôme Leprince
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2020, 19 (4), pp.1800-1811. ⟨10.1021/acs.jproteome.0c00048⟩
Journal of Proteome Research, American Chemical Society, 2020, 19 (4), pp.1800-1811. ⟨10.1021/acs.jproteome.0c00048⟩
International audience; Using an integrated transcriptomic and proteomic approach, we characterized the venom peptidome of the European red ant, Manica rubida. We identified 13 "myrmicitoxins" that share sequence similarities with previously identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37dd64b0396edc34445db921cd7aca8
https://doi.org/10.1021/acs.jproteome.0c00048
https://doi.org/10.1021/acs.jproteome.0c00048
Autor:
Valentine Barassé, Nathan Téné, Christophe Klopp, Françoise Paquet, Niklas Tysklind, Valérie Troispoux, Hadrien Lalägue, Jérôme Orivel, Benjamin Lefranc, Jérôme Leprince, Martin Kenne, Maurice Tindo, Michel Treilhou, Axel Touchard, Elsa Bonnafé
Publikováno v:
Insect Biochemistry and Molecular Biology. 151:103876
Among ants, Myrmicinae represents the most speciose subfamily. The venom composition previously described for these social insects is extremely variable, with alkaloids predominant in some genera while, conversely, proteomics studies have revealed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08d6e7ba0d74fe648004f7e4f8073bf
https://doi.org/10.1016/j.ibmb.2022.103876
https://doi.org/10.1016/j.ibmb.2022.103876