Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Axel Sigurdsson"'
1
Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial
Autor: Paul M Ridker, Jean G MacFadyen, Brendan M Everett, Peter Libby, Tom Thuren, Robert J Glynn, John Kastelein, Wolfgang Koenig, Jacques Genest, Alberto Lorenzatti, John Varigos, Peter Siostrzonek, Peter Sinnaeve, Francisco Fonseca, Jose Nicolau, Nina Gotcheva, Huo Yong, Miguel Urina-Triana, Davor Milicic, Renata Cifkova, Riina Vettus, Stephan D Anker, Athanasios J Manolis, Fernando Wyss, Tamas Forster, Axel Sigurdsson, Prem Pais, Alessandro Fucili, Hisao Ogawa, Hiroaki Shimokawa, Irina Veze, Birute Petrauskiene, Leon Salvador, Jan Hein Cornel, Tor Ole Klemsdal, Felix Medina, Andrzej Budaj, Luminita Vida-Simiti, Zhanna Kobalava, Petar Otasevic, Daniel Pella, Mitja Lainscak, Ki-Bae Seung, Patrick Commerford, Mikael Dellborg, Marc Donath, Juey-Jen Hwang, Hakan Kultursay, Marcus Flather, Christie Ballantyne, Seth Bilazarian, William Chang, Cara East, Les Forgosh, Barry Harris, Monica Ligueros
Publikováno v: Lancet, 391(10118), 319-328. Elsevier Limited
Background: Canakinumab, a monoclonal antibody targeting interleukin-1β reduces inflammation and cardiovascular event rates with no effect on lipid concentrations. However, it is uncertain which patient groups benefit the most from treatment and whe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35120ce9f670c69048ad08ff07b1c5c4
https://pubmed.ncbi.nlm.nih.gov/29188815
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2
Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
Autor: Paul M Ridker, Jean G MacFadyen, Tom Thuren, Brendan M Everett, Peter Libby, Robert J Glynn, Paul Ridker, Alberto Lorenzatti, Henry Krum, John Varigos, Peter Siostrzonek, Peter Sinnaeve, Francisco Fonseca, Jose Nicolau, Nina Gotcheva, Jacques Genest, Huo Yong, Miguel Urina-Triana, Davor Milicic, Renata Cifkova, Riina Vettus, Wolfgang Koenig, Stephan D Anker, Athanasios J Manolis, Fernando Wyss, Tamas Forster, Axel Sigurdsson, Prem Pais, Alessandro Fucili, Hisao Ogawa, Hiroaki Shimokawa, Irina Veze, Birute Petrauskiene, Leon Salvador, John Kastelein, Jan Hein Cornel, Tor Ole Klemsdal, Felix Medina, Andrzej Budaj, Luminita Vida-Simiti, Zhanna Kobalava, Petar Otasevic, Daniel Pella, Mitja Lainscak, Ki-Bae Seung, Patrick Commerford, Mikael Dellborg, Marc Donath, Juey-Jen Hwang, Hakan Kultursay, Marcus Flather, Christie Ballantyne, Seth Bilazarian, William Chang, Cara East, Brendan Everett, Les Forgosh, Robert Glynn, Barry Harris, Monica Ligueros, Erin Bohula, Bindu Charmarthi, Susan Cheng, Sherry Chou, Jacqueline Danik, Graham McMahon, Bradley Maron, MingMing Ning, Benjamin Olenchock, Reena Pande, Todd Perlstein, Aruna Pradhan, Natalia Rost, Aneesh Singhal, Viviany Taqueti, Nancy Wei, Howard Burris, Angela Cioffi, Anne Marie Dalseg, Nilanjan Ghosh, Julie Gralow, Tina Mayer, Hope Rugo, Vance Fowler, Ajit P Limaye, Sara Cosgrove, Donald Levine, Renato Lopes, John Scott, Robert Hilkert, Georgia Tamesby, Carolyn Mickel, Brian Manning, Julian Woelcke, Monique Tan, Sheryl Manfreda, Tom Ponce, Jane Kam, Ravinder Saini, Kehur Banker, Thomas Salko, Panjat Nandy, Ronda Tawfik, Greg O'Neil, Shobha Manne, Pravin Jirvankar, Shankar Lal, Deepak Nema, Jaison Jose, Rory Collins, Kent Bailey, Roger Blumenthal, Helen Colhoun, Bernard Gersh
Publikováno v: Lancet (London, England). 390(10105)
Inflammation in the tumour microenvironment mediated by interleukin 1β is hypothesised to have a major role in cancer invasiveness, progression, and metastases. We did an additional analysis in the Canakinumab Anti-inflammatory Thrombosis Outcomes S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812cc417728b9562fe3fc374d1a8746d
https://pubmed.ncbi.nlm.nih.gov/30370085
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3
Diagnostic accuracy of 64-slice multidetector CT for detection of in-stent restenosis in an unselected, consecutive patient population
Autor: Karl Andersen, Udo Hoffmann, Thorarinn Gudnason, Jonina Gudjonsdottir, Sam J. Lehman, Axel Sigurdsson, Sigurpall S. Scheving, C. Michael Gibson, Kristjan Eyjolfsson, Birna Jónsdóttir, Sigurdis Haraldsdottir
Publikováno v: European Journal of Radiology. 76:188-194
Objectives To investigate the diagnostic accuracy of 64-slice multidetector computed tomography (64-CT) for detection of in-stent restenosis (ISR) in an unselected, consecutive patient population. Background Detection of in-stent restenosis by cardia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a676e36b141debdfc5f1995c6ad759b
https://doi.org/10.1016/j.ejrad.2009.05.030
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4
The role of neurohormonal activation in chronic heart failure and postmyocardial infarction
Autor: Karl Swedberg, Axel Sigurdsson
Publikováno v: American Heart Journal. 132:229-234
Chronic heart failure is a disabling and lethal disorder with high incidence and prevalence in Western societies. Treatment with angiotensin-converting enzyme (ACE) inhibitors and heart transplantations diminish both mortality and morbidity, although
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157a7d9b0c074d9addd72e409ed65648
https://doi.org/10.1016/s0002-8703(05)80004-3
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6
Short- and long-term neurohormonal activation following acute myocardial infarction
Autor: Peter Held, Axel Sigurdsson, Karl Swedberg
Publikováno v: American Heart Journal. 126:1068-1075
Plasma levels of atrial natriuretic peptide (ANP), angiotensin II, aldosterone, and catecholamines were followed for 1 month and then for 4 to 6 months in 55 patients with acute myocardial infarction. Plasma hormones were highest within the first 24
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f167c1ae47060f1b34d31d495d05729
https://doi.org/10.1016/0002-8703(93)90656-t
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7
Enalaprilat in acute myocardial infarction: tolerability and effects on the renin-angiotensin system
Autor: Axel Sigurdsson, Karl Swedberg, Peter Held, Gull Andersson
Publikováno v: International Journal of Cardiology. 33:115-124
We treated 48 patients with intravenous enalaprilat within 24 hours from the onset of acute myocardial infarction. Concomitant therapy included thrombolytic treatment (29), intravenous metoprolol (34), intravenous nitroglycerin (16) and intravenous f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7861b74f85454d9ccb67dcef6b524131
https://doi.org/10.1016/0167-5273(91)90159-m
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9
Prevention of congestive heart failure by ACE inhibition in patients with acute myocardial infarction
Autor: Axel Sigurdsson, Karl Swedberg
Publikováno v: Journal of cardiovascular risk. 2(5)
Ischaemic heart disease is a major cause of chronic heart failure in Western societies. Despite some progress in the treatment of heart failure, it is still a disabling disorder with both high mortality and high morbidity. The incidence of chronic he
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b983f211c8ea83434500666b1c57769
https://pubmed.ncbi.nlm.nih.gov/8749267
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