Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Axel R. Wintzen"'
Autor:
Jan J.G.M. Verschuuren, Fieke M.E. Cox, Carla S P van Rijswijk, Monique Reijnierse, Umesh A. Badrising, Axel R. Wintzen
Publikováno v:
Rheumatology, 50(6), 1153-1161
Objective. To analyse whether MRI of upper and lower extremity muscles in a large patient group with sporadic IBM (sIBM) is of additional value in the diagnostic work-up of sIBM. Methods. Thirty-two sIBM patients were included. Magnetic resonance (MR
Autor:
Marc H. De Baets, Jan J.G.M. Verschuuren, Angela Vincent, Axel R. Wintzen, Peter C. M. Molenaar, W. Pascale ter Beek, Mario Losen, Pilar Martinez-Martinez, Erik H. Niks, Sjoerd G. van Duinen
Publikováno v:
The American Journal of Pathology. 175:1536-1544
Muscle-specific tyrosine kinase (MuSK) is essential for clustering of acetylcholine receptors (AChRs) at embryogenesis and likely also important for maintaining synaptic structure in adult muscle. In 5 to 7% of myasthenia gravis (MG) cases, the patie
Autor:
U.A. Badrising, Axel R. Wintzen, Bernard M. J. Uitdehaag, M. de Visser, W. L. van der Pol, Jessica E. Hoogendijk, M. Blokland‐Fromme, J. van de Vlekkert, I. M. Bronner, Jeanette H. W. Leusen
Publikováno v:
Tissue antigens, 73(6), 586-589. Wiley-Blackwell
Bronner, I F, Hoogendijk, JE, de Visser, M, van de Vlekkert, J, Badrising, U A, Wintzen, A R, Uitdehaag, B M J, Blokland-Fromme, M, Leusen, J H & van der Pol, W L 2009, ' Association of the leukocyte immunoglobulin G (Fc gamma) receptor IIIa-158V/F polymorphism with inflammatory myopathies in Dutch patients ', Tissue Antigens, vol. 73, no. 6, pp. 586-589 . https://doi.org/10.1111/j.1399-0039.2009.01236.x
Tissue Antigens, 73(6), 586. Wiley-Blackwell
Tissue Antigens, 73(6), 586-589. Wiley-Blackwell
Bronner, I F, Hoogendijk, JE, de Visser, M, van de Vlekkert, J, Badrising, U A, Wintzen, A R, Uitdehaag, B M J, Blokland-Fromme, M, Leusen, J H & van der Pol, W L 2009, ' Association of the leukocyte immunoglobulin G (Fc gamma) receptor IIIa-158V/F polymorphism with inflammatory myopathies in Dutch patients ', Tissue Antigens, vol. 73, no. 6, pp. 586-589 . https://doi.org/10.1111/j.1399-0039.2009.01236.x
Tissue Antigens, 73(6), 586. Wiley-Blackwell
Tissue Antigens, 73(6), 586-589. Wiley-Blackwell
Leukocytes are involved in the pathogenesis of idiopathic inflammatory myopathies (IIMs). Immunoglobulin G (IgG) receptors (FcgammaR) link the specificity of IgG to the effector functions of leukocytes. Several FcgammaR subclasses display functional
Clinical fluctuations in MuSK myasthenia gravis are related to antigen-specific IgG4 instead of IgG1
Autor:
Angela Vincent, Y van Leeuwen, Friedo W. Dekker, Axel R. Wintzen, Jan J.G.M. Verschuuren, C.M. Jol-van der Zijde, Erik H. Niks, M.J.D. van Tol, Paul W. Wirtz, Maria Isabel Leite
Publikováno v:
Journal of Neuroimmunology, 195(1-2), 151-156. ELSEVIER SCIENCE BV
We studied the longitudinal relation between disease severity and titers of antigen-specific IgG subclasses in sera of patients with myasthenia gravis and antibodies to Muscle Specific Kinase (MuSK MG). Six patients were included of whom 55 samples h
Autor:
Pieter A. van Doorn, Jan J.G.M. Verschuuren, Umesh A. Badrising, C. G. Faber, Johannes C. Van Houwelingen, Aeiko E. de Jager, Marianne de Visser, Sjoerd G. van Duinen, Jessica E. Hoogendijk, Marion L.C. Maat-Schieman, Baziel G.M. van Engelen, Peter J. Koehler, Axel R. Wintzen
Publikováno v:
Journal of Neurology, 252, 12, pp. 1448-54
Journal of neurology, 252(12), 1448-1454. D. Steinkopff-Verlag
Journal of Neurology, 252, 1448-1454. D. Steinkopff-Verlag
Journal of Neurology, 252, 1448-54
Journal of neurology, 252(12), 1448-1454. D. Steinkopff-Verlag
Journal of Neurology, 252, 1448-1454. D. Steinkopff-Verlag
Journal of Neurology, 252, 1448-54
Contains fulltext : 48412.pdf (Publisher’s version ) (Closed access) The clinical features of inclusion body myositis (IBM) were of minor importance in the design of consensus diagnostic criteria, mainly because of controversial views on the specif
Publikováno v:
Muscle & Nerve. 32:226-229
We studied whether a difference exists in the development of symptoms of the Lambert-Eaton myasthenic syndrome (LEMS) between patients with or without small cell lung cancer (SCLC). We assessed symptoms in 38 LEMS patients, 13 with SCLC, by interview
Publikováno v:
Journal of Neuroimmunology. 140:194-197
Non-paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS) is an antibody-mediated autoimmune disorder, in which genetically determined interleukin-10 (Il-10) and tumor necrosis factor-alpha (TNF-alpha) could play a role in the susceptibility for th
Autor:
Hein Putter, Paul W. Wirtz, Jan J.G.M. Verschuuren, Luc N. A. Willems, Marianne G. Nijnuis, Joey J. Brahim, Mohammad Sotodeh, Axel R. Wintzen
Publikováno v:
Journal of Neurology. 250:698-701
We studied the epidemiology of myasthenia gravis (MG) and the Lambert-Eaton myasthenic syndrome (LEMS), and their association with small cell lung carcinoma (SCLC) and thymoma, in a well defined region of the Netherlands. Available data on all the pa
Publikováno v:
Clinical Neurology and Neurosurgery. 104:359-363
To compare the clinical features of patients with the Lambert-Eaton myasthenic syndrome (LEMS) associated with carcinoma, with patients having LEMS but no cancer, reports on LEMS patients were analyzed systematically. Cancer was detected (CD group) i