Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Axel Römer"'
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103043- (2024)
Diabetes mellitus is a non-communicable metabolic disease hallmarked by chronic hyperglycemia caused by beta-cell failure. Diabetic complications affect the vasculature and result in macro- and microangiopathies, which account for a significantly inc
Externí odkaz:
https://doaj.org/article/20a97cc4e9964a08a6b910faddd9237f
Autor:
Sebastian Friedrich Petry, Axel Römer, Divya Rawat, Lara Brunner, Nina Lerch, Mengmeng Zhou, Rekha Grewal, Fatemeh Sharifpanah, Heinrich Sauer, Gunter Peter Eckert, Thomas Linn
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 788 (2022)
Free fatty acids (FFA), hyperglycemia, and inflammatory cytokines are major mediators of β-cell toxicity in type 2 diabetes mellitus, impairing mitochondrial metabolism. Glutaredoxin 5 (Glrx5) is a mitochondrial protein involved in the assembly of i
Externí odkaz:
https://doaj.org/article/2b653b0c057a4e43b9e283b413ef6a35
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 293 (2021)
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated
Externí odkaz:
https://doaj.org/article/7d08a1a8df834f7380f598eb8b671d80
Publikováno v:
Antioxidants, Vol 10, Iss 293, p 293 (2021)
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::74390066e36cd90a00de137c33ad7c03
https://www.mdpi.com/2076-3921/10/2/293
https://www.mdpi.com/2076-3921/10/2/293
Autor:
Martin Radtke, Hans-Dietrich Heilmann, Dennis E. Kyle, Karl H. Rieckmann, Karl Schmeer, Michael D. Edstein, Axel Römer, Man-Ki Cheung, Wolfram Steinke, Richard K. Haynes, Brian L. Robinson, Lauren Rattray, Jörg Dr. Stetter, Simon L. Croft, Bernhard Beckermann, Livia Vivas, Gabriele Schmuck, Lindsay B. Stewart, Ute Wollborn, Barbara M. Kotecka, Wai-Lun Lam, Ho-Wai Chan, Wallace Peters, Michael Gerisch, Burkhard Fugmann, Ho-Ning Wong
Publikováno v:
Angewandte Chemie. 118:2136-2142
Artemisinin - the next generation: Efficacies of artemisone against the malaria parasite are substantially greater than those of the current artemisinin "gold standard", artesunate. Also, in contrast to most current artemisinins it displays low lipop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4322e81202de71e9c93ecbedaac3ce86
https://doi.org/10.1002/ange.200503071
https://doi.org/10.1002/ange.200503071
Publikováno v:
FEBS Letters. 509:446-450
The major auxin-binding protein (ZmERabp1) from maize (Zea mays L.) has been structurally characterized. We determined the position of a disulfide bridge in ZmERabp1 by mass-spectrometric analysis. We show that Cys2 and Cys61 are covalently linked an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0b2b51865e0f6ba32ac8b5ad3775c1
https://doi.org/10.1016/s0014-5793(01)03196-9
https://doi.org/10.1016/s0014-5793(01)03196-9
Autor:
Brian L. Robinson, Karl H. Rieckmann, Dennis E. Kyle, Hans-Dietrich Heilmann, Gabriele Schmuck, Michael Gerisch, Simon L. Croft, Martin Radtke, Bernhard Beckermann, Lauren Rattray, Karl Schmeer, Lindsay B. Stewart, Wallace Peters, Barbara M. Kotecka, Wai-Lun Lam, Livia Vivas, Richard K. Haynes, Ute Wollborn, Jörg Dr. Stetter, Burkhard Fugmann, Wolfram Steinke, Michael D. Edstein, Man-Ki Cheung, Ho-Wai Chan, Axel Römer, Ho-Ning Wong
Publikováno v:
Angewandte Chemie. 118:2041-2041
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bb9ff885c08188494ed18522abc3adb
https://doi.org/10.1002/ange.200690045
https://doi.org/10.1002/ange.200690045
Autor:
Livia Vivas, Ute Wollborn, Hans-Dietrich Heilmann, Martin Radtke, Axel Römer, Lauren Rattray, Michael D. Edstein, Wallace Peters, Karl Schmeer, Michael Gerisch, Simon L. Croft, Man-Ki Cheung, Burkhard Fugmann, Ho-Wai Chan, Jörg Dr. Stetter, Barbara M. Kotecka, Dennis E. Kyle, Wai-Lun Lam, Ho-Ning Wong, Wolfram Steinke, Brian L. Robinson, Gabriele Schmuck, Bernhard Beckermann, Richard K. Haynes, Karl H. Rieckmann, Lindsay B. Stewart
Publikováno v:
Angewandte Chemie International Edition. 45:1989-1989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fae19b5c09fce6a2b998eaf5bba971d7
https://doi.org/10.1002/anie.200690045
https://doi.org/10.1002/anie.200690045
Publikováno v:
Prostaglandins. 31:1029-1048
Ebselen, a new organoselenium compound with pronounced anti-inflammatory properties, selectively inhibits the formation of leukotriene B4 in human and porcine leukocytes with half-maximal inhibition at 4.0 and 2.7 mumol/1, respectively. The underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da225ec2dd5085ef2b98a382e81bfc34
https://doi.org/10.1016/0090-6980(86)90207-8
https://doi.org/10.1016/0090-6980(86)90207-8
Publikováno v:
Planta Medica. 52:468-473
352 callus cultures - most of them from different plant species - were screened for antiinflammatory activity with the mouse macrophage chemiluminescence assay, an IN VITRO cellular test system. Only two of the secondary metabolite fractions from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b86d3a755b2231d34d084c2d69998b1f
https://doi.org/10.1055/s-2007-969256
https://doi.org/10.1055/s-2007-969256