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pro vyhledávání: '"Axel Obermeier"'
Autor:
Axel Obermeier, Philipp Grohs
Publikováno v:
Journal of Approximation Theory. 237:30-95
In Grohs and Obermeier (2015), the authors discussed the existence of numerically feasible solvers for advection equations that run in optimal computational complexity. In this paper, we complete the last remaining requirement to achieve this goal
Publikováno v:
SIAM Journal on Multiscale Modeling and Simulation
This paper introduces an FFT-based implementation of a fast finite ridgelet transform which we call FFRT. Inspired by recent work where it was shown that ridgelet discretizations of linear transport equations can be easily preconditioned by diagonal
Autor:
Günter Krause, Olga Mitina, Axel Obermeier, Nicola Simon, Karin Forster, Markus Warmuth, Michael Hallek
Publikováno v:
Annals of Hematology. 87:183-193
The constitutive tyrosine kinase activity of the BCR-ABL fusion protein plays a crucial role in the pathogenesis of chronic myeloid leukemia and promotes growth factor-independent survival of hematopoietic cells. In 32D cells, expression levels of re
Publikováno v:
Annals of Hematology. 86:777-785
The receptor tyrosine kinase (RTK) Flt3 is expressed in early hematopoietic progenitor cells and stimulates their growth. Due to frequent mutations in the Flt3 gene in patients with acute myeloid leukemia (AML), Flt3 is regarded as a potential therap
Autor:
Axel Obermeier, C Miksch, Olga Mitina, Günter Krause, J Ellwart, R Tavares, Michael Hallek, A Hausherr, M Schäffer
Publikováno v:
Oncogene 26, 4987-4998 (2007)
An acidic domain (AD) of gp130 was previously found to interact with the Src family kinase (SFK) Hck. Here, the influence of myristoylated peptides derived from this AD was assessed in the mouse myeloma cell line, 7TD1. The IL-6-dependent growth of 7
Autor:
Philipp Grohs, Axel Obermeier
Publikováno v:
Curves and Surfaces ISBN: 9783319228037
Curves and Surfaces
University of Vienna-u:cris
Curves and Surfaces
University of Vienna-u:cris
In this paper we present an overview of a novel method for the numerical solution of linear transport equations, which is based on ridgelets and has been introduced in [12, 16]. Such equations arise for instance in radiative transfer or in phase cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b62feca0efe4c6596ed6abbcd2540de
https://doi.org/10.1007/978-3-319-22804-4_18
https://doi.org/10.1007/978-3-319-22804-4_18
Publikováno v:
The EMBO Journal. 17:4328-4339
The serine/threonine kinase p21-activated kinase (PAK) has been implicated as a downstream effector of the small GTPases Rac and Cdc42. While these GTPases evidently induce a variety of morphological changes, the role(s) of PAK remains elusive. Here
Autor:
Stefan Mayr, Paul Dietl, Axel Obermeier, Hans Grunicke, Inge Tinhofer, Franz Hochholdinger, Karl Maly
Publikováno v:
Journal of Biological Chemistry. 271:30505-30509
Stimulation by epidermal growth factor (EGF) of NIH3T3 cells overexpressing the EGF receptor (EGFR) results in a release of Ca2+ from internal stores. Ca2+ release is followed by an influx of extracellular calcium which can be recorded by the influx
Autor:
Ben Lewis Margolis, A Ullrich, Joseph Schlessinger, Axel Obermeier, Ivan Dikic, A. Batzer, Pamela Blaikie
Publikováno v:
Journal of Biological Chemistry. 270:15125-15129
Shc is an adaptor protein that contains two phosphotyrosine-binding domains, a Src homology 2 (SH2) domain and the newly described phosphotyrosine interaction (PI) domain. Shc interacts with several tyrosine-phosphorylated proteins and is itself tyro
Autor:
Mike Hutton, Hanno Roder, Barbara Monse, Gabriele Hübinger, Cynthia Zehr, Jason L. Eriksen, Nikolaus Plesnila, Sylvie Le Corre, Mei Yue, Heidi Sahagún, Hans Klafki, Eileen McGowan, Jada Lewis, Dennis W. Dickson, Axel Obermeier, Pierfausto Seneci
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 103(25)
An orally bioavailable and blood–brain barrier penetrating analog of the kinase inhibitor K252a was able to prevent the typical motor deficits in the tau (P301L) transgenic mouse model (JNPL3) and markedly reduce soluble aggregated hyperphosphoryla