Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Axel Nohturfft"'
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 11, Pp 2151-2158 (2004)
A scintillation proximity assay has been developed to study the endosomal trafficking of radiolabeled cholesterol in living cells. Mouse macrophages were cultured in the presence of tritiated cholesterol and scintillant microspheres. Microspheres wer
Externí odkaz:
https://doaj.org/article/654c0864bab14be2ad7a1ee31b6b0999
Autor:
Sandipan Chatterjee, Joseph D Szustakowski, Nirmala R Nanguneri, Craig Mickanin, Mark A Labow, Axel Nohturfft, Kumlesh K Dev, Rajeev Sivasankaran
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5197 (2009)
BackgroundLipid metabolism in mammals is orchestrated by a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control the expression of genes required for the uptake and synthesis of cholesterol, fatty aci
Externí odkaz:
https://doaj.org/article/f9c070563cbb4b3cb0db1a17be7bb0ba
Autor:
Larissa Milano, Clara F. Charlier, Rafaela Andreguetti, Thomas Cox, Eleanor Healing, Marcos P. Thomé, Ruan M. Elliott, Leona D. Samson, Jean-Yves Masson, Guido Lenz, João Antonio P. Henriques, Axel Nohturfft, Lisiane B. Meira
Alkylating agents damage DNA and proteins and are widely used in cancer chemotherapy. While cellular responses to alkylation-induced DNA damage have been explored, knowledge of how alkylation affects global cellular stress responses is sparse. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab79291f04602e5e4c92c1aa4cfa839
https://openaccess.sgul.ac.uk/id/eprint/114155/1/2022_Milano_PNAS.pdf
https://openaccess.sgul.ac.uk/id/eprint/114155/1/2022_Milano_PNAS.pdf
Autor:
Guido Lenz, Marcos P. Thomé, Clara F. Charlier, Larissa Milano, Lisiane B. Meira, Jean-Yves Masson, Eleanor Healing, Ruan M. Elliott, João Antonio Pêgas Henriques, Leona D. Samson, Axel Nohturfft, Rafaela Andreguetti, Thomas Cox
Alkylating agents damage DNA and proteins and are widely used in cancer chemotherapy. While the cellular responses to alkylation-induced DNA damage have been explored, knowledge of how alkylation damage affects global cellular stress responses is sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c49c301dac1be6a2c38abeb35abd7d
https://doi.org/10.1101/2021.03.31.437844
https://doi.org/10.1101/2021.03.31.437844
Autor:
Nicoletta Charolidi, Gillian W. Cockerill, Evelyn Torsney, Grisha Pirianov, Axel Nohturfft, Stuart Pearce, Ken Laing
Publikováno v:
Journal of Vascular Research. 52:81-93
Peroxisome proliferator-activated receptor γ agonists have been shown to inhibit angiotensin II (AngII)-induced experimental abdominal aortic aneurysms. Macrophage infiltration to the vascular wall is an early event in this pathology, and therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2622663067d03a9ff8501a9db3bffae5
https://doi.org/10.1159/000430986
https://doi.org/10.1159/000430986
Autor:
Shao Chong Zhang, Axel Nohturfft
Publikováno v:
Annual Review of Cell and Developmental Biology. 25:539-566
Bilayer synthesis during membrane biogenesis involves the concerted assembly of multiple lipid species, requiring coordination of the level of lipid synthesis, uptake, turnover, and subcellular distribution. In this review, we discuss some of the sal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cef5a69035da152d65486a02554441
https://doi.org/10.1146/annurev.cellbio.24.110707.175344
https://doi.org/10.1146/annurev.cellbio.24.110707.175344
Autor:
Arnab Chakravarti, Ji Young Yoo, Jianjie Ma, Chunming Cheng, Junfeng Liu, Axel Nohturfft, Etienne Lefai, Xiang Cheng, Peng Hu, Feng Geng, Vanessa Euthine, Deliang Guo, Xiaoning Wu, Balveen Kaur, Peng Ru, Jeffrey Yunhua Guo
Publikováno v:
Cancer Cell
Cancer Cell, Elsevier, 2015, 28 (5), pp.569-81. ⟨10.1016/j.ccell.2015.09.021⟩
Cancer Cell, Elsevier, 2015, 28 (5), pp.569-81. ⟨10.1016/j.ccell.2015.09.021⟩
International audience; Tumorigenesis is associated with increased glucose consumption and lipogenesis, but how these pathways are interlinked is unclear. Here, we delineate a pathway in which EGFR signaling, by increasing glucose uptake, promotes N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93942de674cef76c6907fcd8f0a7edc
https://hal.archives-ouvertes.fr/hal-01850543
https://hal.archives-ouvertes.fr/hal-01850543
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 11, Pp 2151-2158 (2004)
A scintillation proximity assay has been developed to study the endosomal trafficking of radiolabeled cholesterol in living cells. Mouse macrophages were cultured in the presence of tritiated cholesterol and scintillant microspheres. Microspheres wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad6dac3bbdf009a88e4b2b2744b56d7
https://doi.org/10.1194/jlr.d400011-jlr200
https://doi.org/10.1194/jlr.d400011-jlr200
Autor:
Nicoletta Charolidi, Evelyn Torsney, Grisha Pirianov, Ken Laing, Axel Nohturfft, Gillian W Cockerill
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Aims: Perixosome proliferator-activated receptor γ (PPARγ) agonists have been shown to inhibit Angiotensin II-induced experimental abdominal aortic aneurysms. Since increased macrophage infiltration in the vascular wall is a hallmark for initiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b065cc3fd8a888a49bab97a91918590
https://doi.org/10.1161/atvb.34.suppl_1.483
https://doi.org/10.1161/atvb.34.suppl_1.483
Publikováno v:
Cell. 102:315-323
SREBPs exit the ER in a complex with SCAP. Together, they move to the Golgi where SREBP is cleaved, releasing a fragment that activates genes encoding lipid biosynthetic enzymes. Sterols block ER exit, preventing cleavage, decreasing transcription, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe63830ed438e9f0123915ea0b91f1d
https://doi.org/10.1016/s0092-8674(00)00037-4
https://doi.org/10.1016/s0092-8674(00)00037-4