Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Axel K Walch"'
1
Akademický článek
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.
Autor: Andras Franko, Olivier R Baris, Eva Bergschneider, Christine von Toerne, Stefanie M Hauck, Michaela Aichler, Axel K Walch, Wolfgang Wurst, Rudolf J Wiesner, Ian C D Johnston, Martin Hrabĕ de Angelis
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82392 (2013)
To better understand molecular mechanisms regulating changes in metabolism, as observed e.g. in diabetes or neuronal disorders, the function of mitochondria needs to be precisely determined. The usual isolation methods such as differential centrifuga
Externí odkaz: https://doaj.org/article/c4ffcc322db246078027a6b3eea701fe
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2
Akademický článek
Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models
Autor: Jurate Skerniskyte, Céline Mulet, Antonin C. André, Mark C. Anderson, Louise Injarabian, Achim Buck, Verena M. Prade, Philippe J. Sansonetti, Sophie Reibel-Foisset, Axel K. Walch, Michel Lebel, Jens Lykkesfeldt, Benoit S. Marteyn
Publikováno v: Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTShigella spp. are the causative agents of bacterial dysentery and shigellosis, mainly in children living in developing countries. The study of Shigella entire life cycle in vivo and the evaluation of vaccine candidates’ protective efficacy
Externí odkaz: https://doaj.org/article/89d9b94eee7e4f86934d999908bc40af
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3
Akademický článek
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice
Autor: Rico Burkhardt, Thomas Gora, Alexander A. Fingerle, Andreas P. Sauter, Felix Meurer, Florian T. Gassert, Sophie Dobiasch, Daniela Schilling, Annette Feuchtinger, Axel K. Walch, Gabriele Multhoff, Julia Herzen, Peter B. Noël, Ernst J. Rummeny, Stephanie E. Combs, Thomas E. Schmid, Franz Pfeiffer, Jan J. Wilkens
Publikováno v: Physics and Imaging in Radiation Oncology, Vol 20, Iss , Pp 11-16 (2021)
Background and Purpose: Radiotherapy of thoracic tumours can lead to side effects in the lung, which may benefit from early diagnosis. We investigated the potential of X-ray dark-field computed tomography by a proof-of-principle murine study in a cli
Externí odkaz: https://doaj.org/article/c4e136775c6a440cb16e1a91eb7e3ace
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4
Akademický článek
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond
Autor: Michael Orth, Valerie Albrecht, Karin Seidl, Linda Kinzel, Kristian Unger, Julia Hess, Lisa Kreutzer, Na Sun, Benjamin Stegen, Alexander Nieto, Jessica Maas, Nicolas Winssinger, Anna A. Friedl, Axel K. Walch, Claus Belka, Horst Zitzelsberger, Maximilian Niyazi, Kirsten Lauber
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Radiotherapy is an essential component of multi-modality treatment of glioblastoma (GBM). However, treatment failure and recurrence are frequent and give rise to the dismal prognosis of this aggressive type of primary brain tumor. A high level of inh
Externí odkaz: https://doaj.org/article/6234a74314e54125a8fc169499ac2566
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5
Akademický článek
Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer
Autor: Xiaopeng Ma, Valerie Phi Van, Melanie A. Kimm, Jaya Prakash, Horst Kessler, Katja Kosanke, Annette Feuchtinger, Michaela Aichler, Aayush Gupta, Ernst J. Rummeny, Michel Eisenblätter, Jens Siveke, Axel K. Walch, Rickmer Braren, Vasilis Ntziachristos, Moritz Wildgruber
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 1, Pp 8-16 (2017)
Integrins play an important role in tumor progression, invasion and metastasis. Therefore we aimed to evaluate a preclinical imaging approach applying ανβ3 integrin targeted hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography (FMT-X
Externí odkaz: https://doaj.org/article/cca4c019ff4249e8a2046ea0dbf7d60d
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6
Akademický článek
Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging approach
Autor: Fabian Lohöfer, Laura Hoffmann, Rebecca Buchholz, Katharina Huber, Almut Glinzer, Katja Kosanke, Annette Feuchtinger, Michaela Aichler, Benedikt Feuerecker, Georgios Kaissis, Ernst J. Rummeny, Carsten Höltke, Cornelius Faber, Franz Schilling, René M. Botnar, Axel K. Walch, Uwe Karst, Moritz Wildgruber
Publikováno v: Heliyon, Vol 4, Iss 4, Pp e00606- (2018)
Background: Molecular MRI is becoming increasingly important for preclinical research. Validation of targeted gadolinium probes in tissue however has been cumbersome up to now. Novel methodology to assess gadolinium distribution in tissue after in vi
Externí odkaz: https://doaj.org/article/c9ad0ab9a9cc434bbf3e3dcd2f49776a
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