Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Axel H. Newton"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Cook, Pask and colleagues describe the ossification of the skull and forelimbs in the developing postnatal fat-tailed dunnart. As one of the most altricial marsupials at birth with a short reproductive cycle and simple lab husbandry, this species is
Externí odkaz:
https://doaj.org/article/cc24a76dbb8f4f44a0d6635d21f2b2eb
Autor:
Axel H. Newton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Studies across vertebrates have revealed significant insights into the processes that drive craniofacial morphogenesis, yet we still know little about how distinct facial morphologies are patterned during development. Studies largely point to evoluti
Externí odkaz:
https://doaj.org/article/3c16ff7451db4289accbd32a5cc13d25
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Newton et al. use microCT data and geometric morphometric analyses to explore the processes underlying the convergently evolved skulls of thylacine and gray wolf. Similarities in growth trajectory are contrasted by differential developmental event ti
Externí odkaz:
https://doaj.org/article/9363bf156ba644bbb9d2565bc4f463fc
Autor:
Axel H. Newton, Andrew J. Pask
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
In this Perspective, Axel Newton and Andrew Pask examine the role of the Runt-related transcription factor 2 (RUNX2) QA repeat during skeletal development and discuss how its emergence and expansion may have facilitated the evolution of morphological
Externí odkaz:
https://doaj.org/article/bb378cdba13e4f178cfdc211deabaaa5
Autor:
Axel H. Newton, Andrew J. Pask
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Changes in gene regulation are widely recognized as an important driver of adaptive phenotypic evolution. However, the specific molecular mechanisms that underpin such changes are still poorly understood. Chromatin state plays an
Externí odkaz:
https://doaj.org/article/b7a43dd165044dad92bb73d04cc50169
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Runt-related transcription factor 2 (RUNX2) is a transcription factor essential for skeletal development. Variation within the RUNX2 polyglutamine / polyalanine (QA) repeat is correlated with facial length within orders of placent
Externí odkaz:
https://doaj.org/article/e2dde52aad734c6ea2be60675795cd89
Autor:
Axel H. Newton, Andrew J. Pask
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01687-0 .
Externí odkaz:
https://doaj.org/article/33336e0f2bf24f909adaaa38ea66a036
Autor:
Axel H. Newton, Frantisek Spoutil, Jan Prochazka, Jay R. Black, Kathryn Medlock, Robert N. Paddle, Marketa Knitlova, Christy A. Hipsley, Andrew J. Pask
Publikováno v:
Royal Society Open Science, Vol 5, Iss 2 (2018)
The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was an iconic Australian marsupial predator that was hunted to extinction in the early 1900s. Despite sharing striking similarities with canids, they failed to evolve many of the specialized
Externí odkaz:
https://doaj.org/article/fb3d6de8f7224dc5bad0655e41ac146b
Between tetrapods the limbs have undergone considerable remodelling to achieve unique adaptive behaviours. The forelimb is an ideal model for exploring the molecular basis of adaptive limb development, as it shows remarkable structural variation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12649bc9af6ef4a9da42634f88b12d1d
https://doi.org/10.1101/2022.11.23.516993
https://doi.org/10.1101/2022.11.23.516993
Publikováno v:
Development (Cambridge, England). 149(18)
The lateral plate mesoderm (LPM) is a transient tissue that produces a diverse range of differentiated structures, including the limbs. However, the molecular mechanisms that drive early LPM specification and development are poorly understood. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcaed2d2294516c8e4974aee75d5cf8
https://pubmed.ncbi.nlm.nih.gov/36093878
https://pubmed.ncbi.nlm.nih.gov/36093878