Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Axel H. Meyer"'
Autor:
Magdalena Kurtyka, Frank Wessely, Sarah Bau, Eseoghene Ifie, Liqun He, Nienke M. de Wit, Alberte Bay Villekjær Pedersen, Maximilian Keller, Caleb Webber, Helga E. de Vries, Olaf Ansorge, Christer Betsholtz, Marijke De Bock, Catarina Chaves, Birger Brodin, Morten S. Nielsen, Winfried Neuhaus, Robert D. Bell, Tamás Letoha, Axel H. Meyer, Germán Leparc, Martin Lenter, Dominique Lesuisse, Zameel M. Cader, Stephen T. Buckley, Irena Loryan, Claus U. Pietrzik
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151406- (2024)
Despite extensive research, targeted delivery of substances to the brain still poses a great challenge due to the selectivity of the blood-brain barrier (BBB). Most molecules require either carrier- or receptor-mediated transport systems to reach the
Externí odkaz:
https://doaj.org/article/24cf1f3bfe6c41b79a62e5eaa26fce38
Autor:
Axel H. Meyer, Thomas M. Feldsien, Mario Mezler, Christopher Untucht, Ramakrishna Venugopalan, Didier R. Lefebvre
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1100 (2023)
The blood-brain barrier (BBB) is a major hurdle for the development of systemically delivered drugs against diseases of the central nervous system (CNS). Because of this barrier there is still a huge unmet need for the treatment of these diseases, de
Externí odkaz:
https://doaj.org/article/45d3488e046e4470a84c1662b355c574
Autor:
Elena Demicheva, Yi-Fang Cui, Philip Bardwell, Stefan Barghorn, Martina Kron, Axel H. Meyer, Martin Schmidt, Björn Gerlach, Mary Leddy, Eve Barlow, Elizabeth O’Connor, Chee-Ho Choi, Lili Huang, Geertruida M. Veldman, Horea Rus, Alireza P. Shabanzadeh, Nardos G. Tassew, Philippe P. Monnier, Thomas Müller, Peter A. Calabresi, Hans Schoemaker, Bernhard K. Mueller
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1887-1898 (2015)
Repulsive guidance molecule A (RGMa) is a potent inhibitor of neuronal regeneration and a regulator of cell death, and it plays a role in multiple sclerosis (MS). In autopsy material from progressive MS patients, RGMa was found in active and chronic
Externí odkaz:
https://doaj.org/article/fd6bc223076f45f18b655b9a1c010a3d
Autor:
Ana M. Basso, Ryuichi Konno, Lynne E. Rueter, Natalie A. Bratcher, Michael E. Ballard, Min Zhang, Axel H. Meyer, Pete Curzon, Kaitlin E. Browman
Publikováno v:
Behavioural Brain Research. 217:81-87
d -amino acid oxidase (DAO), an enzyme that degrades d -serine, has been suggested as a susceptibility factor for schizophrenia. Here we sought to understand more about the behavioral consequence of lacking DAO and the potential therapeutic implicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae80b730b5ab5c3b99377f9b7443662
https://doi.org/10.1016/j.bbr.2010.09.030
https://doi.org/10.1016/j.bbr.2010.09.030
Autor:
Julieta Alfonso, Maria M. Kreuzberg, Johannes A. van Hooft, Hannah Monyer, Jakob von Engelhardt, Dragos Inta, Axel H. Meyer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 105(52), 20994-20999. National Academy of Sciences
Most forebrain GABAergic interneurons in rodents are born during embryonic development in the ganglionic eminences (GE) and migrate tangentially into the cortical plate. A subset, however, continues to be generated postnatally in the subventricular z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f4a7a2d45273e0a588ca15ac8cd9a6
https://hdl.handle.net/11245/1.294187
https://hdl.handle.net/11245/1.294187
Publikováno v:
The Journal of Neuroscience. 27:5633-5642
Acetylcholine is a major neurotransmitter that modulates cortical functions. In addition to basal forebrain neurons that give rise to the principal cholinergic input into the cortex, a second source constituted by intrinsic cholinergic interneurons h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39fcb722a382d7d04c2a860dcfc00cd1
https://doi.org/10.1523/jneurosci.4647-06.2007
https://doi.org/10.1523/jneurosci.4647-06.2007
Autor:
Troy W. Margrie, Hannah Monyer, Winfried Denk, Mazahir T. Hasan, Antonio Caputi, Michael Brecht, Andreas T. Schaefer, Axel H. Meyer
Publikováno v:
Neuron
While electrophysiological recordings from visually identified cell bodies or dendrites are routinely performed in cell culture and acute brain slice preparations, targeted recordings from the mammalian nervous system are currently not possible in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff6390af0cc68fe62259b25af8114fd
Autor:
Andrei Rozov, Miles A. Whittington, István Katona, Axel H. Meyer, Sheriar G. Hormuzdi, Maria Blatow, Hannah Monyer, Antonio Caputi
Publikováno v:
Neuron. 38(5):805-817
GABAergic interneurons can phase the output of principal cells, giving rise to oscillatory activity in different frequency bands. Here we describe a new subtype of GABAergic interneuron, the multipolar bursting (MB) cell in the mouse neocortex. MB ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d00506c4c99499e4461225245ce8b7
Autor:
Daniela Merlo, M. I. Aller, H. E. Jolin, U. Amtmann, Hannah Monyer, Stephen G. Brickley, Alison Jones, M. Paterlini, A. N. J. McKenzie, William Wisden, Axel H. Meyer, Mark Farrant
Publikováno v:
genesis. 36:97-103
Summary: The cerebellum maintains balance and orien-tation, refines motor action, stores motor memories, andcontributes to the timing aspects of cognition. We gen-erated two mouse lines for making Cre recombinase-mediated gene disruptions largely co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02478508344acb08b7afb0363ca12832
https://doi.org/10.1002/gene.10204
https://doi.org/10.1002/gene.10204
Autor:
Jörg R. P. Geiger, Axel H. Meyer, Peter Jonas, Hannah Monyer, Michael Frotscher, Marlene Bartos, Imre Vida
Publikováno v:
Proceedings of the National Academy of Sciences. 99:13222-13227
Networks of GABAergic interneurons are of critical importance for the generation of gamma frequency oscillations in the brain. To examine the underlying synaptic mechanisms, we made paired recordings from “basket cells” (BCs) in different subfiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4b4e6ac2a5056d75d1b339b17389f6
https://doi.org/10.1073/pnas.192233099
https://doi.org/10.1073/pnas.192233099