Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Axel Ekman"'
Autor:
Thomas Eng, Deepanwita Banerjee, Javier Menasalvas, Yan Chen, Jennifer Gin, Hemant Choudhary, Edward Baidoo, Jian Hua Chen, Axel Ekman, Ramu Kakumanu, Yuzhong Liu Diercks, Alex Codik, Carolyn Larabell, John Gladden, Blake A. Simmons, Jay D. Keasling, Christopher J. Petzold, Aindrila Mukhopadhyay
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113087- (2023)
Summary: Maximizing the production of heterologous biomolecules is a complex problem that can be addressed with a systems-level understanding of cellular metabolism and regulation. Specifically, growth-coupling approaches can increase product titers
Externí odkaz:
https://doaj.org/article/44231f8beb664554bcb8285ca80eab71
Autor:
Axel Ekman, Jian-Hua Chen, Bieke Vanslembrouck, Valentina Loconte, Carolyn A. Larabell, Mark A. Le Gros, Venera Weinhardt
Publikováno v:
Advanced Photonics Research, Vol 4, Iss 4, Pp n/a-n/a (2023)
Soft X‐ray tomography offers rapid imaging of whole, single cells with a few tens of nanometers spatial resolution without fixation or labeling. Herein, this technique is limited to specimens about 10 μm thick, such that applications of soft X‐r
Externí odkaz:
https://doaj.org/article/34ab2b85a3cf4a76a5ee7c6e7e7cfd72
Autor:
Jian-Hua Chen, Bieke Vanslembrouck, Valentina Loconte, Axel Ekman, Mirko Cortese, Ralf Bartenschlager, Gerry McDermott, Carolyn A. Larabell, Mark A. Le Gros, Venera Weinhardt
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101176- (2022)
Summary: The protocol describes step-by-step sample preparation, data acquisition, and segmentation of cellular organelles with soft X-ray tomography. It is designed for microscopes built to perform full-rotation data acquisition on specimens in cyli
Externí odkaz:
https://doaj.org/article/2ffd46a8a2e34dd5ae9932cc02244dd6
Autor:
Ludovic Autin, Brett A. Barbaro, Andrew I. Jewett, Axel Ekman, Shruti Verma, Arthur J. Olson, David S. Goodsell
Publikováno v:
QRB Discovery, Vol 3 (2022)
Models of insulin secretory vesicles from pancreatic beta cells have been created using the cellPACK suite of tools to research, curate, construct and visualise the current state of knowledge. The model integrates experimental information from proteo
Externí odkaz:
https://doaj.org/article/b4a4b94ef2a247e4b65ec7d554c42962
Autor:
Angdi Li, Shuning Zhang, Valentina Loconte, Yan Liu, Axel Ekman, Garth J Thompson, Andrej Sali, Raymond C Stevens, Kate White, Jitin Singla, Liping Sun
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0269887 (2022)
Investigating the 3D structures and rearrangements of organelles within a single cell is critical for better characterizing cellular function. Imaging approaches such as soft X-ray tomography have been widely applied to reveal a complex subcellular o
Externí odkaz:
https://doaj.org/article/e34d3f3d819d4259b41e890b26737c8f
Autor:
Jian-Hua Chen, Bieke Vanslembrouck, Axel Ekman, Vesa Aho, Carolyn A. Larabell, Mark A. Le Gros, Maija Vihinen-Ranta, Venera Weinhardt
Publikováno v:
Viruses, Vol 14, Iss 12, p 2651 (2022)
Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells, imaging virus-host interactions at high spatial resolu
Externí odkaz:
https://doaj.org/article/7d1f06bf5cef4e51a946d69fcc3a9b36
Autor:
Vesa Aho, Elina Mäntylä, Axel Ekman, Satu Hakanen, Salla Mattola, Jian-Hua Chen, Venera Weinhardt, Visa Ruokolainen, Beate Sodeik, Carolyn Larabell, Maija Vihinen-Ranta
Publikováno v:
Viruses, Vol 11, Iss 10, p 935 (2019)
During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm. We have shown previously that HSV-1 infection induces the formation
Externí odkaz:
https://doaj.org/article/520d04d11c93468c8523680608e82d5d
Autor:
Thomas T Eng, Deepanwita Banerjee, Javier Menasalvas, Yan Chen, Jennifer Gin, Hemant Choudhary, Edward Baidoo, Jian Hua Chen, Axel Ekman, Ramu Kakumanu, Yuzhong Liu Diercks, Alex Codik, Carolyn Larabell, John Gladden, Blake A Simmons, Jay D Keasling, Christopher J Petzold, Aindrila Mukhopadhyay
While many heterologous molecules can be produced at trace concentrations via microbial bioconversion processes, maximizing their titers, rates, and yields from lignin-derived carbon streams remains challenging. Growth coupling can not only increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f79dcadeba5d71674e3530e6d94edb8b
https://doi.org/10.1101/2023.03.16.532821
https://doi.org/10.1101/2023.03.16.532821
Autor:
Steven Boeynaems, X. Rosa Ma, Vivian Yeong, Garrett M. Ginell, Jian-Hua Chen, Jacob A. Blum, Lisa Nakayama, Anushka Sanyal, Adam Briner, Delphi Van Haver, Jarne Pauwels, Axel Ekman, H. Broder Schmidt, Kousik Sundararajan, Lucas Porta, Keren Lasker, Carolyn Larabell, Mirian A. F. Hayashi, Anshul Kundaje, Francis Impens, Allie Obermeyer, Alex S. Holehouse, Aaron D. Gitler
Positively charged repeat peptides are emerging as key players in neurodegenerative diseases. These peptides can perturb diverse cellular pathways but a unifying framework for how such promiscuous toxicity arises has remained elusive. We used mass-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013c06175ee5e3e890d98431771b7dc9
https://doi.org/10.1101/2023.03.09.531820
https://doi.org/10.1101/2023.03.09.531820
Publikováno v:
Microscopy and Microanalysis. 28:1498-1500