Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Axel E, Kraft"'
Autor:
Axel E. Kraft, Nadja I. Bork, Hariharan Subramanian, Nikoleta Pavlaki, Antonio V. Failla, Bernd Zobiak, Marco Conti, Viacheslav O. Nikolaev
Publikováno v:
Cells, Vol 13, Iss 6, p 476 (2024)
The ubiquitous second messenger 3′,5′-cyclic adenosine monophosphate (cAMP) regulates cardiac excitation-contraction coupling (ECC) by signaling in discrete subcellular microdomains. Phosphodiesterase subfamilies 4B and 4D are critically involved
Externí odkaz:
https://doaj.org/article/c82bc06ba3af4c549615d0745de94c45
Autor:
Juan E. Camacho Londoño, André Marx, Axel E. Kraft, Alexander Schürger, Christin Richter, Alexander Dietrich, Peter Lipp, Lutz Birnbaumer, Marc Freichel
Publikováno v:
Cells, Vol 9, Iss 2, p 322 (2020)
TRPC proteins form cation conducting channels regulated by different stimuli and are regulators of the cellular calcium homeostasis. TRPC are expressed in cardiac cells including cardiac fibroblasts (CFs) and have been implicated in the development o
Externí odkaz:
https://doaj.org/article/29752007b159443c9aeec537c9250d02
Autor:
Filip Berisha, Cristina E. Molina, Jörg W. Wegener, Christiane Jungen, Gerd Hasenfuß, Konrad R. Götz, Stefan Blankenberg, Viacheslav O. Nikolaev, Stephan E. Lehnart, Dirk Westermann, Svenja Warnke, Alexander M. Bernhardt, Axel E. Kraft, Sören Brandenburg, Diana Lindner, Hariharan Subramanian, Ulrike Pape, Evaldas Girdauskas, Johannes Petersen, Christian Meyer, André Rüffer
Publikováno v:
Circulation Research. 129:81-94
Rationale: 3′,5′-cAMP is a ubiquitous second messenger which, upon β-AR (β-adrenergic receptor) stimulation, acts in microdomains to regulate cardiac excitation-contraction coupling by activating phosphorylation of calcium handling proteins. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::377795a2d8e01f6b9ceb37188007272f
https://doi.org/10.1161/circresaha.120.318234
https://doi.org/10.1161/circresaha.120.318234
Autor:
Axel E Kraft, Juan E. Camacho Londoño, Peter Lipp, Lutz Birnbaumer, André Marx, Alexander Schürger, Marc Freichel, Alexander Dietrich, Christin Richter
Publikováno v:
Cells, Vol 9, Iss 2, p 322 (2020)
Cells
Volume 9
Issue 2
Cells. 2020, 9(2)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cells
Volume 9
Issue 2
Cells. 2020, 9(2)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
TRPC proteins form cation conducting channels regulated by different stimuli and are regulators of the cellular calcium homeostasis. TRPC are expressed in cardiac cells including cardiac fibroblasts (CFs) and have been implicated in the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e65857f41bd7a5a6f40b4464b313e8
https://www.mdpi.com/2073-4409/9/2/322
https://www.mdpi.com/2073-4409/9/2/322
Autor:
Juan E, Camacho Londoño, André, Marx, Axel E, Kraft, Alexander, Schürger, Christin, Richter, Alexander, Dietrich, Peter, Lipp, Lutz, Birnbaumer, Marc, Freichel
Publikováno v:
Cells
TRPC proteins form cation conducting channels regulated by different stimuli and are regulators of the cellular calcium homeostasis. TRPC are expressed in cardiac cells including cardiac fibroblasts (CFs) and have been implicated in the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::094762a5341d100fd0227e5e7fe37881
https://pubmed.ncbi.nlm.nih.gov/32013125
https://pubmed.ncbi.nlm.nih.gov/32013125
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2041
The assessment of local concentrations of extracellular ATP (eATP) at the site of receptor binding remains a challenge in the field of purinergic signaling. In many cases, biosensors exploiting the principle of Förster resonance energy transfer (FRE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba110aa736ccb6ba734cb4dbe1ad7be2
https://pubmed.ncbi.nlm.nih.gov/31646492
https://pubmed.ncbi.nlm.nih.gov/31646492
Publikováno v:
Methods in Molecular Biology ISBN: 9781493997169
The assessment of local concentrations of extracellular ATP (eATP) at the site of receptor binding remains a challenge in the field of purinergic signaling. In many cases, biosensors exploiting the principle of Forster resonance energy transfer (FRET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::032a08f8fb0238e19a6806381147b9a9
https://doi.org/10.1007/978-1-4939-9717-6_16
https://doi.org/10.1007/978-1-4939-9717-6_16
Autor:
Viacheslav O. Nikolaev, Stephan E. Lehnart, Ulrike Pape, K R Goetz, Cindy Meyer, Christiane Jungen, Stefan Blankenberg, Filip Berisha, Svenja Warnke, J W Wegener, Diana Lindner, Axel E. Kraft, Gerd Hasenfuss, Dirk Westermann
RationaleCyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger which, upon β-adrenergic receptor (β-AR) stimulation, acts in microdomains to regulate cardiac excitation-contraction coupling by activating the cAMP-dependent protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5d1c50210822218555822c2c20e5c3
https://doi.org/10.1101/623934
https://doi.org/10.1101/623934
Autor:
Axel E. Kraft, Alexander Froese, Viacheslav O. Nikolaev, William Fuller, Zeynep Bastug-Özel, Peter Wright, Julia Gorelik, Jacqueline Howie, Michael J. Shattock, Davor Pavlovic
Aims Cyclic adenosine monophosphate (cAMP) regulates cardiac excitation–contraction coupling by acting in microdomains associated with sarcolemmal ion channels. However, local real time cAMP dynamics in such microdomains has not been visualized bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae610aa068c2b6f2c8c6a4e6d7ecf1e
https://europepmc.org/articles/PMC6383061/
https://europepmc.org/articles/PMC6383061/
Publikováno v:
Circulation Research. 121
Phosphodiesterase subfamilies 4B and 4D are critically involved in the regulation of cAMP signaling in mammalian cardiomyocytes. Alterations in activity of these enzymes in human hearts have been shown to result in arrhythmia and heart failure. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::949de1143efb81d75b528d846628716d
https://doi.org/10.1161/res.121.suppl_1.319
https://doi.org/10.1161/res.121.suppl_1.319