Exergoeconomic analysis of a pumped heat electricity storage system based on a Joule/Brayton cycle

Autor: Axel Dietrich, Frank Dammel, Peter Stephan

Publikováno v: Energy Science & Engineering, Vol 9, Iss 5, Pp 645-660 (2021)

Abstract Storing electrical energy in the form of thermal energy, pumped heat electricity storage (PHES) systems are a location‐independent alternative to established storage technologies. Detailed analyses, considering the transient operation of P

Externí odkaz: https://doaj.org/article/c454c4ac39414374a2a5dba1cf296529

The role of insulin resistance in experimental diabetic retinopathy-Genetic and molecular aspects.

Autor: Patrick Järgen, Axel Dietrich, Andreas W Herling, Hans-Peter Hammes, Paulus Wohlfart

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0178658 (2017)

BackgroundDiabetic retinopathy is characterized by defects in the retinal neurovascular unit. The underlying mechanisms of impairment-including reactive intermediates and growth-factor dependent signalling pathways and their possible interplay are in

Externí odkaz: https://doaj.org/article/b9f92aca53364becbb43e5f3919ef8b2

AB0018 TRANSCRIPTOMIC CHARACTERIZATION OF SINGLE PATHOGENIC MEMORY B CELLS IN RHEUMATOID ARTHRITIS

Autor: Hans Scherer, Axel Dietrich, Emanuele de Rinaldis, Deimante Simaite, René E. M. Toes, Virginia Savova, Linda M. Slot, Claus Reimertz, Michel Didier, Matthias Herrmann, Carsten Struebing, Veeranagouda Yaligara, Frank O. Nestle

Publikováno v: Abstracts Accepted for Publication.

Background Autoantigen-specific B lymphocytes are crucial players in the development of rheumatoid arthritis (RA). Despite the fact that ACPA+ autoreactive memory B cells have been observed in the majority of RA patients for a long time, their proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37b75aeb979c877ea58498795aa5f837
https://doi.org/10.1136/annrheumdis-2019-eular.1947

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Autor: Dorret I. Boomsma, Søren Brunak, Adem Y. Dawed, Gonneke Willemsen, Mark I. McCarthy, Martijn van de Bunt, Karina Banasik, Leen M 't Hart, Valborg Gudmundsdottir, Mark H. H. Kramer, Jorge Ferrer, Eco J. C. de Geus, Axel Dietrich, Caroline Brorsson, Ramneek Gupta, A.M.C. Simonis-Bik, Anubha Mahajan, Elisabeth M. W. Eekhoff, Hans-Ulrich Häring, Thomas Hübschle, Christopher J. Groves, Andreas Fritsche, Harald Staiger, Joris Deelen, Karla V. Allebrandt, Helle Krogh Pedersen, Nienke van Leeuwen, Ewan R. Pearson

Publikováno v: PLoS ONE, 13(1)
PLoS One
PLoS ONE
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886, pp. 1-19 . https://doi.org/10.1371/journal.pone.0189886
PLoS ONE, 13(1):e0189886. Public Library of Science
PLoS ONE, Vol 13, Iss 1, p e0189886 (2018)
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C A, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study ', P L o S One, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, de Bunt, M V, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & t Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886 . https://doi.org/10.1371/journal.pone.0189886
Gudmundsdottir, V, Pedersen, H K, Allebrandt, K V, Brorsson, C, van Leeuwen, N, Banasik, K, Mahajan, A, Groves, C J, van de Bunt, M, Dawed, A Y, Fritsche, A, Staiger, H, Simonis-Bik, A M C, Deelen, J, Kramer, M H H, Dietrich, A, Hübschle, T, Willemsen, G, Häring, H-U, de Geus, E J C, Boomsma, D I, Eekhoff, E M W, Ferrer, J, McCarthy, M I, Pearson, E R, Gupta, R, Brunak, S & 't Hart, L M 2018, ' Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion : A DIRECT study ', PLoS ONE, vol. 13, no. 1, e0189886, pp. e0189886 . https://doi.org/10.1371/journal.pone.0189886

Glucagon-like peptide 1 (GLP-1) stimulated insulin secretion has a considerable heritable component as estimated from twin studies, yet few genetic variants influencing this phenotype have been identified. We performed the first genome-wide associati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9489b2fe6f8e6eb1c32fb0ecab54e1
http://hdl.handle.net/1887/76801

Hyperglycaemic memory affects the neurovascular unit of the retina in a diabetic mouse model

Autor: Hans-Peter Hammes, Patrick Friedrichs, Grietje Molema, Andrea Schlotterer, Thomas Linn, Axel Dietrich, Paulus Wohlfart, Carsten Sticht, M Kolibabka

Publikováno v: Diabetologia, 60(7), 1354-1358. SPRINGER

Aims/hypothesis: The aim of this study was to evaluate damage to the neurovascular unit in a mouse model of hyperglycaemic memory.Methods: A streptozotocin-induced mouse model of diabetes (C57BL/6J background) received insulin-releasing pellets and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b8bb1f8dd927117b582f65f4e2efaa
https://pubmed.ncbi.nlm.nih.gov/28321468