Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Axel Dalhoff"'
Autor:
Axel Dalhoff
Publikováno v:
Interdisciplinary Perspectives on Infectious Diseases, Vol 2012 (2012)
This paper on the fluoroquinolone resistance epidemiology stratifies the data according to the different prescription patterns by either primary or tertiary caregivers and by indication. Global surveillance studies demonstrate that fluoroquinolone re
Externí odkaz:
https://doaj.org/article/7fc30205cd3e490fb6a96b7719239a6f
Autor:
Axel Dalhoff
Publikováno v:
Infection
Purpose Advances in structural biology, genetics, bioinformatics, etc. resulted in the availability of an enormous pool of information enabling the analysis of the ancestry of pro- and eukaryotic genes and proteins. Methods This review summarizes fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba08bff1a9018770838050ae7bd7e2bb
http://europepmc.org/articles/PMC7737717
http://europepmc.org/articles/PMC7737717
Autor:
Axel Dalhoff
Publikováno v:
Krankenhaushygiene up2date. 12:299-314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd5dd30ae19bc72b81e111680a19c8c
https://doi.org/10.1055/s-0043-111615
https://doi.org/10.1055/s-0043-111615
Autor:
Axel Dalhoff
Publikováno v:
Krankenhaushygiene up2date. 12:179-193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b66a523af9b7f1f92521a4e4aea0e9a
https://doi.org/10.1055/s-0043-105461
https://doi.org/10.1055/s-0043-105461
Publikováno v:
International Journal of Antimicrobial Agents. 55:105809
Use of pharmacodynamic in vitro models provides more clinically relevant information about the activities of antibiotics than static endpoints. Several models are used to simulate pharmacokinetics by dilution of the medium. It is discussed whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e6dccfa1580226a4c5ab620408b1d7
https://doi.org/10.1016/j.ijantimicag.2019.09.013
https://doi.org/10.1016/j.ijantimicag.2019.09.013
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Two phase II studies were performed with patients with uncomplicated urinary tract infections (uUTIs) and complicated urinary tract infections (cUTIs) or acute pyelonephritis (PN) to compare finafloxacin (300 mg twice a day [b.i.d.] orally for uUTI a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607811822eac11d195ccad20b34824a2
https://doi.org/10.1128/aac.02325-17
https://doi.org/10.1128/aac.02325-17
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Finafloxacin is a novel fluoroquinolone with increased antibacterial activity at acidic pH and reduced susceptibility to several resistance mechanisms. A phase II study revealed a good efficacy/safety profile in patients with complicated urinary trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4464cbbe2fc631c53bf10c7025e864
https://doi.org/10.1128/aac.02328-17
https://doi.org/10.1128/aac.02328-17
Autor:
Axel Dalhoff
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
This review summarizes evidence that the impact of protein binding of the activity of antibiotics is multifaceted and more complex than indicated by the numerical value of protein binding alone. A plethora of studies has proven that protein binding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8ae13ddb5dc152454550289ed08735
https://doi.org/10.1128/aac.01663-17
https://doi.org/10.1128/aac.01663-17
Autor:
Axel Dalhoff, Stuart B. Levy
Publikováno v:
International Journal of Antimicrobial Agents. 45:564-567
Natamycin is a poorly soluble, polyene macrolide antifungal agent used in the food industry for the surface treatment of cheese and sausages. This use is not of safety concern. However, highly soluble natamycin–cyclodextrin inclusion complexes have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053ad4b15465afb49564a4049c9a052c
https://doi.org/10.1016/j.ijantimicag.2015.02.011
https://doi.org/10.1016/j.ijantimicag.2015.02.011
Publikováno v:
Antimicrobial Agents and Chemotherapy
The pharmacodynamics of finafloxacin, ciprofloxacin, and levofloxacin against extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae isolates were compared. Since quinolones lose activity in acidic media, and particularly in urine, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c653e3cd6522d936c87887a0e46ebf90
https://doi.org/10.1128/aac.02446-16
https://doi.org/10.1128/aac.02446-16