Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Axel Bethke"'
Autor:
Axel Bethke
„Wer sich entschlossen hat, alt zu werden, sollte frühzeitig vorsorgen. Geld reicht da nicht.“ (Axel Bethke) Zwölfeinhalb Jahre ist Grassy, als der Autor ihn im Internet entdeckt. Dieser – auf Menschenjahre umgerechnet etwa genauso alt wie Gr
Autor:
Sydney L. Campbell, Kathleen J. Dumas, Joshua C. Judkins, Anna M. Zimmerman, Adam Antebi, Frank C. Schroeder, Joshua Wollam, Parag Mahanti, Axel Bethke, Patrick J. Hu, Neelanjan Bose
Publikováno v:
Cell Metab
SummarySmall-molecule ligands of nuclear hormone receptors (NHRs) govern the transcriptional regulation of metazoan development, cell differentiation, and metabolism. However, the physiological ligands of many NHRs remain poorly characterized, primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbdcf6b9f4909acf5843300192a6971
Autor:
Rabia U. Malik, Parag Mahanti, Donha Park, Frank C. Schroeder, Anna Zimmermann, Andreas H. Ludewig, Donald L. Riddle, Frank Doering, Bennett W. Fox, Axel Bethke, Yevgeniy Izrayelit
Publikováno v:
Proceedings of the National Academy of Sciences. 110:5522-5527
Lifespan in Caenorhabditis elegans , Drosophila , and mice is regulated by conserved signaling networks, including the insulin/insulin-like growth factor 1 (IGF-1) signaling cascade and pathways depending on sirtuins, a family of NAD + -dependent dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbc9d6879b9732228fbca7f96082a48
https://doi.org/10.1073/pnas.1214467110
https://doi.org/10.1073/pnas.1214467110
Autor:
Rishi K. Somvanshi, Inish O'Doherty, Frank C. Schroeder, Donald L. Riddle, Donha Park, Axel Bethke, Ujendra Kumar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(25)
A chemically diverse family of small-molecule signals, the ascarosides, control developmental diapause (dauer), olfactory learning, and social behaviors of the nematode model organism, Caenorhabditis elegans . The ascarosides act upstream of conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a1b92dd8b615ff0cfb49e84a324e70
https://pubmed.ncbi.nlm.nih.gov/22665789
https://pubmed.ncbi.nlm.nih.gov/22665789
Publikováno v:
Science
In response to small-molecule signals such as retinoids or steroids, nuclear receptors activate gene expression to regulate development in different tissues. MicroRNAs turn off target gene expression within cells by binding complementary regions in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c645a5f8f07ec3cec2376b1bd8689d
https://pubmed.ncbi.nlm.nih.gov/19342589
https://pubmed.ncbi.nlm.nih.gov/19342589
Publikováno v:
Org Lett
Synthesis and testing of dafachronic acid A ( 1) and its derivatives 2 and 3 have revealed that 1, and not a further oxidation product, is the natural ligand for the DAF-12 receptor of Caenorhabditis elegans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d337cf4ded57918ee8caf5fee98adf
https://europepmc.org/articles/PMC2659505/
https://europepmc.org/articles/PMC2659505/
Publikováno v:
Applied microbiology and biotechnology. 71(1)
2-Methylcitrate synthase (2-MCS1) and citrate synthase (CS) of Ralstonia eutropha strain H16 were separated by affinity chromatography and analyzed for their substrate specificities. 2-MCS1 used not only the primary substrate propionyl-CoA but also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79667ffcb5ced52ceb093c32b88f34ca
https://pubmed.ncbi.nlm.nih.gov/16133321
https://pubmed.ncbi.nlm.nih.gov/16133321
Autor:
Cindy Weitzel, Adam Antebi, Corinna Kober-Eisermann, Kerstin Neubert, Andreas H. Ludewig, Axel Bethke, Birgit Gerisch, Harald Hutter
Publikováno v:
Genes Dev
Genes and Development
Genes and Development
Environmental cues transduced by an endocrine network converge on Caenorhabditis elegans nuclear receptor DAF-12 to mediate arrest at dauer diapause or continuous larval development. In adults, DAF-12 selects long-lived or short-lived modes. How thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9300e839ce0e9489ac4ec00152d2d968
https://europepmc.org/articles/PMC515290/
https://europepmc.org/articles/PMC515290/
Publikováno v:
Organic Letters; Jul2008, Vol. 10 Issue 16, p3643-3645, 3p