Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Axel A. Ekman"'
Autor:
Eleonora de Klerk, Yini Xiao, Christopher H. Emfinger, Mark P. Keller, David I. Berrios, Valentina Loconte, Axel A. Ekman, Kate L. White, Rebecca L. Cardone, Richard G. Kibbey, Alan D. Attie, Matthias Hebrok
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Insulin secretion from pancreatic β cells is essential to the maintenance of glucose homeostasis. Defects in this process result in diabetes. Identifying genetic regulators that impair insulin secretion is crucial for the identification of novel the
Externí odkaz:
https://doaj.org/article/b4b5dbeb38934b90baccd9d13f8ca114
Autor:
Soumya G. Remesh, Subhash C. Verma, Jian-Hua Chen, Axel A. Ekman, Carolyn A. Larabell, Sankar Adhya, Michal Hammel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
HU is among the most conserved and abundant nucleoid-associated proteins in eubacteria. Here the authors investigate the role of histone-like proteins (HU) in the 3D organization of the bacteria DNA and show via soft X-ray tomography the process of n
Externí odkaz:
https://doaj.org/article/c5ba312025fb45d398cd579a218e4808
Autor:
Simon Leclerc, Alka Gupta, Visa Ruokolainen, Jian-Hua Chen, Kari Kunnas, Axel A Ekman, Henri Niskanen, Ilya Belevich, Helena Vihinen, Paula Turkki, Ana J Perez-Berna, Sergey Kapishnikov, Elina Mäntylä, Maria Harkiolaki, Eric Dufour, Vesa Hytönen, Eva Pereiro, Tony McEnroe, Kenneth Fahy, Minna U Kaikkonen, Eija Jokitalo, Carolyn A Larabell, Venera Weinhardt, Salla Mattola, Vesa Aho, Maija Vihinen-Ranta
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011829 (2024)
Viruses target mitochondria to promote their replication, and infection-induced stress during the progression of infection leads to the regulation of antiviral defenses and mitochondrial metabolism which are opposed by counteracting viral factors. Th
Externí odkaz:
https://doaj.org/article/487e2f24f96c4045ac1e8396fe49fa50
Autor:
Venera Weinhardt, Jian-Hua Chen, Axel A Ekman, Jessica Guo, Soumya G Remesh, Michal Hammel, Gerry McDermott, Weilun Chao, Sharon Oh, Mark A Le Gros, Carolyn A Larabell
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227601 (2020)
The diversity of living cells, in both size and internal complexity, calls for imaging methods with adaptable spatial resolution. Soft x-ray tomography (SXT) is a three-dimensional imaging technique ideally suited to visualizing and quantifying the i
Externí odkaz:
https://doaj.org/article/3df436e81ff942be8f8daf9bcf191b2d
Autor:
Valentina Loconte, Jian‐Hua Chen, Bieke Vanslembrouck, Axel A. Ekman, Gerry McDermott, Mark A. Le Gros, Carolyn A. Larabell
Publikováno v:
The FASEB Journal. 37
Developing in silico models that accurately reflect a whole, functional cell is an ongoing challenge in biology. Current efforts bring together mathematical models, probabilistic models, visual representations, and data to create a multi-scale descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15dd841f007c01586565e469c35c0e5
https://doi.org/10.1096/fj.202200253r
https://doi.org/10.1096/fj.202200253r
Autor:
Coale TH; Ocean Sciences Department, University of California, Santa Cruz, CA, USA., Loconte V; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Turk-Kubo KA; Ocean Sciences Department, University of California, Santa Cruz, CA, USA., Vanslembrouck B; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Mak WKE; Ocean Sciences Department, University of California, Santa Cruz, CA, USA., Cheung S; Institute of Marine Biology and Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan., Ekman A; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA., Chen JH; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Hagino K; Marine Core Research Institute, Kochi University, Nankoku, Kochi, Japan., Takano Y; Marine Core Research Institute, Kochi University, Nankoku, Kochi, Japan., Nishimura T; Fisheries Technology Institute, Japan Fisheries Research and Education Agency, Hatsukaichi, Hiroshima, Japan.; Laboratory of Aquatic Environmental Science, Faculty of Agriculture and Marine Science, Kochi University, Nankoku, Kochi, Japan., Adachi M; Laboratory of Aquatic Environmental Science, Faculty of Agriculture and Marine Science, Kochi University, Nankoku, Kochi, Japan., Le Gros M; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Larabell C; Department of Anatomy, School of Medicine, University of California, San Francisco, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Zehr JP; Ocean Sciences Department, University of California, Santa Cruz, CA, USA.
Publikováno v:
Science (New York, N.Y.) [Science] 2024 Apr 12; Vol. 384 (6692), pp. 217-222. Date of Electronic Publication: 2024 Apr 11.
Autor:
Egebjerg JM; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark.; Department of Mathematics and Computer Science, University of Southern Denmark, Odense M, Denmark., Szomek M; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Thaysen K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Juhl AD; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Kozakijevic S; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Werner S; Department of X‑Ray Microscopy, Helmholtz-Zentrum Berlin, Germany and Humboldt-Universität zu Berlin, Institut für Physik, Berlin, Germany., Pratsch C; Department of X‑Ray Microscopy, Helmholtz-Zentrum Berlin, Germany and Humboldt-Universität zu Berlin, Institut für Physik, Berlin, Germany., Schneider G; Department of X‑Ray Microscopy, Helmholtz-Zentrum Berlin, Germany and Humboldt-Universität zu Berlin, Institut für Physik, Berlin, Germany., Kapishnikov S; SiriusXT, 9A Holly Ave. Stillorgan Industrial Park, Blackrock, Co, Dublin, Ireland., Ekman A; Department of Biological and Environmental Science and Nanoscience Centre, University of Jyväskylä, Jyväskylä, Finland., Röttger R; Department of Mathematics and Computer Science, University of Southern Denmark, Odense M, Denmark., Wüstner D; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark.
Publikováno v:
Autophagy [Autophagy] 2024 Apr; Vol. 20 (4), pp. 902-922. Date of Electronic Publication: 2023 Oct 31.
Autor:
Eng T; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Banerjee D; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Menasalvas J; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Chen Y; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Gin J; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Choudhary H; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biomanufacturing and Biomaterials Department, Sandia National Laboratories, Livermore, CA, USA., Baidoo E; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Chen JH; Department of Anatomy, University of California, San Francisco, San Francisco, CA, USA; National Center for X-ray Tomography, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Ekman A; Department of Anatomy, University of California, San Francisco, San Francisco, CA, USA; National Center for X-ray Tomography, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Kakumanu R; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Diercks YL; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Codik A; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Larabell C; Department of Anatomy, University of California, San Francisco, San Francisco, CA, USA; National Center for X-ray Tomography, Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Gladden J; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biomanufacturing and Biomaterials Department, Sandia National Laboratories, Livermore, CA, USA., Simmons BA; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Keasling JD; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; QB3 Institute, University of California, Berkeley, 5885 Hollis Street, 4th Floor, Emeryville, CA 94608, USA; Department of Chemical & Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA; Novo Nordisk Foundation Center for Biosustainability, Technical University Denmark, 2970 Horsholm, Denmark; Synthetic Biochemistry Center, Institute for Synthetic Biology, Shenzhen Institutes for Advanced Technologies, Shenzhen, China., Petzold CJ; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Mukhopadhyay A; The Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, CA 94608, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: amukhopadhyay@lbl.gov.
Publikováno v:
Cell reports [Cell Rep] 2023 Sep 26; Vol. 42 (9), pp. 113087. Date of Electronic Publication: 2023 Sep 03.
Autor:
Boeynaems S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, TX 77030, USA.; Center for Alzheimer's and Neurodegenerative Diseases (CAND), Texas Children's Hospital, Houston, TX 77030, USA.; Dan L Duncan Comprehensive Cancer Center (DLDCCC), Baylor College of Medicine, Houston, TX 77030, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Ma XR; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Yeong V; Department of Chemical Engineering, Columbia University, New York, NY, 10027, USA., Ginell GM; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA., Chen JH; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Blum JA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Nakayama L; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Sanyal A; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA., Briner A; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD 4072, Australia., Haver DV; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Pauwels J; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Ekman A; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Schmidt HB; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Sundararajan K; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA., Porta L; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil., Lasker K; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Larabell C; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California, San Francisco, CA 94143, USA., Hayashi MAF; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Sao Paulo, Brazil., Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Computer Science, Stanford University, Stanford, CA 94305, USA., Impens F; VIB-UGent Center for Medical Biotechnology, 9000 Gent, Belgium.; VIB Proteomics Core, 9000 Gent, Belgium.; Department of Biochemistry, Ghent University, 9000 Gent, Belgium., Obermeyer A; Department of Chemical Engineering, Columbia University, New York, NY, 10027, USA., Holehouse AS; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA., Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 09. Date of Electronic Publication: 2023 Mar 09.
Autor:
Chen JH; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA., Vanslembrouck B; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA., Ekman A; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Aho V; Department of Biological and Environmental Science, Nanoscience Center, University of Jyvaskyla, 40014 Jyvaskyla, Finland., Larabell CA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA., Le Gros MA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA., Vihinen-Ranta M; Department of Biological and Environmental Science, Nanoscience Center, University of Jyvaskyla, 40014 Jyvaskyla, Finland., Weinhardt V; Centre for Organismal Studies, University of Heidelberg, 69120 Heidelberg, Germany.
Publikováno v:
Viruses [Viruses] 2022 Nov 27; Vol. 14 (12). Date of Electronic Publication: 2022 Nov 27.