Wall teichoic acid substitution with glucose governs phage susceptibility of Staphylococcus epidermidis

Autor: Christian Beck, Janes Krusche, Anna Notaro, Axel Walter, Lara Kränkel, Anneli Vollert, Regine Stemmler, Johannes Wittmann, Martin Schaller, Christoph Slavetinsky, Christoph Mayer, Cristina De Castro, Andreas Peschel

Publikováno v: mBio, Vol 15, Iss 4 (2024)

ABSTRACTThe species- and clone-specific susceptibility of Staphylococcus cells for bacteriophages is governed by the structures and glycosylation patterns of wall teichoic acid (WTA) glycopolymers. The glycosylation-dependent phage-WTA interactions i

Externí odkaz: https://doaj.org/article/00260f1e15e944578a9349b13820b6cd

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

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Publikováno v: In The Lancet 18-24 May 2024 403(10440):2100-2132

UmetaFlow: an untargeted metabolomics workflow for high-throughput data processing and analysis

Autor: Eftychia E. Kontou, Axel Walter, Oliver Alka, Julianus Pfeuffer, Timo Sachsenberg, Omkar S. Mohite, Matin Nuhamunada, Oliver Kohlbacher, Tilmann Weber

Publikováno v: Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-12 (2023)

Abstract Metabolomics experiments generate highly complex datasets, which are time and work-intensive, sometimes even error-prone if inspected manually. Therefore, new methods for automated, fast, reproducible, and accurate data processing and derepl

Externí odkaz: https://doaj.org/article/3eac90bcea8046f0b2c75985a30b6984

BCL::MP-Fold: membrane protein structure prediction guided by EPR restraints

Autor: Fischer, Axel Walter, Alexander, Nathan Scott, Woetzel, Nils, Karakas, Mert, Weiner, Brian, Meiler, Jens

For many membrane proteins the determination of their topology remains a challenge for methods like X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy. Electron paramagnetic resonance (EPR) spectroscopy has evolved as an alternat

Externí odkaz: http://arxiv.org/abs/1503.09182

UmetaFlow: An untargeted metabolomics workflow for high-throughput data processing and analysis

Autor: Eftychia Eva Kontou, Axel Walter, Timo Sachsenberg, Tilmann Weber, Oliver Alka, Julianus Pfeuffer, Matin Nuhamunada, Omkar Mohite, Oliver Kohlbacher

Publikováno v: Kontou, E E, Walter, A, Alka, O, Pfeuffer, J, Sachsenberg, T, Mohite, O S, Nuhamunada, M, Kohlbacher, O & Weber, T 2023, ' UmetaFlow : an untargeted metabolomics workflow for high-throughput data processing and analysis ', Journal of Cheminformatics, vol. 15, 52 . https://doi.org/10.1186/s13321-023-00724-w

Metabolomics experiments generate highly complex datasets, which are time and work-intensive, sometimes even error-prone if inspected manually. Therefore, new methods for automated, fast, reproducible, and accurate data processing and dereplication a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42768bcc0bdb98824df709466c0750d6
https://doi.org/10.26434/chemrxiv-2022-z0t4g-v2