Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Axel, Künstner"'
Autor:
Marco L. Freschi, Axel Künstner, Gianna Huber, Ines Stölting, Hauke Busch, Misa Hirose, Walter Raasch
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionTreatment of rodents with the AT1 blocker (ARB) telmisartan (TEL) has an anti-adipose effect. Among other mechanisms, we also have attributed the anti-adipose action to diet-independent alterations in gut microbiota. Thus, we aimed here t
Externí odkaz:
https://doaj.org/article/e96eb19e48e7441fa6f4a6893a4644ac
Autor:
Anke Fähnrich, Zhala Gasimova, Yamil Maluje, Fabian Ott, Helen Sievert, Stephanie Fliedner, Niklas Reimer, Axel Künstner, Niklas Gebauer, Maxim Kebenko, Nikolas von Bubnoff, Jutta Kirfel, Verena-Wilbeth Sailer, Christoph Röcken, Bjoern Konukiewitz, Wolfram Klapper, Alex Frydrychowicz, Sam Mogadas, Gerdt Huebner, Hauke Busch, Cyrus Khandanpour
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tenosynovial giant cell tumor (TGCT) is a rare type of tumor that originates from the synovium of joints and tendon sheaths. It is characterized by recurring genetic abnormalities, often involving the CSF1 gene. Common symptoms include pain and swell
Externí odkaz:
https://doaj.org/article/40b1b72d680f47c2a37a910d9ae3158d
Autor:
Mohammad Tahseen Al Bataineh, Axel Künstner, Nihar Ranjan Dash, Habiba S. Alsafar, Mohab Ragab, Franziska Schmelter, Christian Sina, Hauke Busch, Saleh Mohamed Ibrahim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Type 2 Diabetes Mellitus has reached epidemic levels globally, and several studies have confirmed a link between gut microbial dysbiosis and aberrant glucose homeostasis among people with diabetes. While the assumption is that abnormal metab
Externí odkaz:
https://doaj.org/article/6b8fcce7819843b181c0bb8d98c0265e
Autor:
Mirja Thomsen, Axel Künstner, Inken Wohlers, Michael Olbrich, Tim Lenfers, Takafumi Osumi, Yotaro Shimazaki, Koji Nishifuji, Saleh M. Ibrahim, Adrian Watson, Hauke Busch, Misa Hirose
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Background Like its human counterpart, canine atopic dermatitis (cAD) is a chronic relapsing condition; thus, most cAD-affected dogs will require lifelong treatment to maintain an acceptable quality of life. A potential intervention is modul
Externí odkaz:
https://doaj.org/article/a5ecf7d3a23b4323812d4f9418f8f296
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-5 (2023)
Abstract Despite the availability of batch effect correcting algorithms (BECA), no comprehensive tool that combines batch correction and evaluation of the results exists for microbiome datasets. This work outlines the Microbiome Batch Effects Correct
Externí odkaz:
https://doaj.org/article/1593e25066c24f1db831c55a64785d80
Autor:
Friederike Praus, Axel Künstner, Thorben Sauer, Michael Kohl, Katharina Kern, Steffen Deichmann, Ákos Végvári, Tobias Keck, Hauke Busch, Jens K. Habermann, Timo Gemoll
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Colorectal cancer (CRC) is one of the most prevalent cancers, with over one million new cases per year. Overall, prognosis of CRC largely depends on the disease stage and metastatic status. As precision oncology for patients with
Externí odkaz:
https://doaj.org/article/a3b31ca7db6f42b1a6ed7d76b3f8c000
Autor:
Lukas Sturm, Misa Hirose, Laura Stolz, Michael Schultheiss, Katharina Zoldan, Marlene Reincke, Jan Patrick Huber, Rafael Kaeser, Tobias Boettler, Robert Thimme, Elisabeth Albert, Hauke Busch, Axel Künstner, Dominik Bettinger
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Recent studies have linked proton pump inhibitor (PPI) treatment to increased complications of cirrhosis, such as bacterial infections and hepatic encephalopathy. However, the underlying pathophysiological mechanisms remain unclear. The pres
Externí odkaz:
https://doaj.org/article/e841650409eb40b89821619cd8c12ecb
Autor:
Hanno Maximilian Witte, Axel Künstner, Emil Chteinberg, Francesco Piazza, Gaël Roué, Niklas Gebauer
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/f64fcf610b5144b99e6e50ce43fb5500
Autor:
Benedikt Färber, Olga Lapshyna, Axel Künstner, Michael Kohl, Thorben Sauer, Kira Bichmann, Benjamin Heckelmann, Jessica Watzelt, Kim Honselmann, Louisa Bolm, Meike ten Winkel, Hauke Busch, Hendrik Ungefroren, Tobias Keck, Timo Gemoll, Ulrich F. Wellner, Rüdiger Braun
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeChemotherapy is pivotal in the multimodal treatment of pancreatic ductal adenocarcinoma (PDAC). Technical advances unveiled a high degree of inter- and intratumoral heterogeneity. We hypothesized that intratumoral heterogeneity (ITH) impacts r
Externí odkaz:
https://doaj.org/article/f332737a1dce4103ad86d6bd40b36538
Autor:
Verónica Calonga-Solís, Michael Olbrich, Fabian Ott, Gabriel Adelman Cipolla, Danielle Malheiros, Axel Künstner, Ticiana D.J. Farias, Carolina M. Camargo, Maria Luiza Petzl-Erler, Hauke Busch, Anke Fähnrich, Danillo G. Augusto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPrimarily driven by autoreactive B cells, pemphigus foliaceus (PF) is an uncommon autoimmune blistering skin disease of sporadic occurrence worldwide. However, PF reaches a prevalence of 3% in the endemic areas of Brazil, the highest ever
Externí odkaz:
https://doaj.org/article/fc7efbff4f714207a2a1a86ec59d339e