Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Awen, Gallimore"'
Autor:
Martin J. Scurr, George Lippiatt, Lorenzo Capitani, Kirsten Bentley, Sarah N. Lauder, Kathryn Smart, Michelle S. Somerville, Tara Rees, Richard J. Stanton, Awen Gallimore, James P. Hindley, Andrew Godkin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible S
Externí odkaz:
https://doaj.org/article/d478f34a0e4948beb39a42e0ae302a63
Autor:
Stefan Milutinovic, Jun Abe, Emma Jones, Inken Kelch, Kathryn Smart, Sarah N. Lauder, Michelle Somerville, Carl Ware, Andrew Godkin, Jens V. Stein, Gib Bogle, Awen Gallimore
Publikováno v:
Cancer Research Communications. 2:1641-1656
High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f421d60081ee93185577183075cec8d
https://doi.org/10.1158/2767-9764.crc-21-0123
https://doi.org/10.1158/2767-9764.crc-21-0123
Autor:
Emma Jones, Andrew Godkin, Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown prom
Externí odkaz:
https://doaj.org/article/03253b8693d64d3c84a6f9eeb342088e
Autor:
H. Angharad Watson, Ruban R. P. Durairaj, Julia Ohme, Markella Alatsatianos, Hanan Almutairi, Rebar N. Mohammed, Miriam Vigar, Sophie G. Reed, Stephen J. Paisey, Christopher Marshall, Awen Gallimore, Ann Ager
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The homing molecule, L-selectin (CD62L), is commonly used as a T cell activation marker, since expression is downregulated following engagement of the T cell receptor. Studies in mice have shown that CD62L+ central memory T cells are better at contro
Externí odkaz:
https://doaj.org/article/3f7f91648a5449e7a2df294752c4ba54
Autor:
Stefan Milutinovic, Awen Gallimore
Publikováno v:
Discovery Immunology.
High endothelial venules (HEVs) are specialised postcapillary venules that specifically serve to recruit circulating lymphocytes to secondary lymphoid organs (SLOs) where cognate antigens can be encountered, and immune responses can be initiated. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba2e27cf9606e36ea1426153b6319a0c
https://doi.org/10.1093/discim/kyad006
https://doi.org/10.1093/discim/kyad006
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
Naïve LN HEV Characterisation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4605883c7af350a0f9e8855dd1699ab
https://doi.org/10.1158/2767-9764.22546265
https://doi.org/10.1158/2767-9764.22546265
Autor:
Awen Gallimore, Andrew Godkin, Robert Andrews, William J. Watkins, Matthew J. Smalley, Rhiannon French, James P. Hindley, Howard Kendrick, Stefan Milutinovic, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Emma Jones, Alexander Greenshields-Watson, Ana Pires
Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d486884604d87cab99475a87091a408
https://doi.org/10.1158/2326-6066.22543605.v1
https://doi.org/10.1158/2326-6066.22543605.v1
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e518ba5cab64bb4d5b9752e29a0b0da
https://doi.org/10.1158/2767-9764.c.6551132.v1
https://doi.org/10.1158/2767-9764.c.6551132.v1
Autor:
Awen Gallimore, Andrew Godkin, Robert Andrews, William J. Watkins, Matthew J. Smalley, Rhiannon French, James P. Hindley, Howard Kendrick, Stefan Milutinovic, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Emma Jones, Alexander Greenshields-Watson, Ana Pires
The nature of the tumor microenvironment (TME) influences the ability of tumor-specific T cells to control tumor growth. In this study, we performed an unbiased comparison of the TME of regulatory T-cell (Treg)–replete and Treg-depleted carcinogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd1b36ae44d938b2dc48a4d25e36406
https://doi.org/10.1158/2326-6066.c.6550332
https://doi.org/10.1158/2326-6066.c.6550332
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
Global overview of intra-tumoral HEVs in a 4T1 regressor tumour following PI-3065 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466fe82b9967c7ea1f9fe51d9113da4d
https://doi.org/10.1158/2767-9764.22546244.v1
https://doi.org/10.1158/2767-9764.22546244.v1