Zobrazeno 1 - 10
of 317
pro vyhledávání: '"Aw, Harris"'
Autor:
Michael Kohn, Ilario Lazzaro, Simon Clarke, Margaret Charles, Leanne M. Williams, Cyril Latimer, AW Harris, Kerri J. Brown, Pamela J. Marsh
Publikováno v:
Acta neuropsychiatrica. 18(6)
Publikováno v:
Clinical Science. 86:203-208
1. Nitric oxide (NO) is a potent endogenous vasodilator and plays a role in the control of resting vascular tone. Patients with cirrhosis have a hyperdynamic circulation with reduced blood pressure and decreased peripheral resistance, and it is possi
Publikováno v:
Gut. 64:A93.1-A93
Introduction Clinical relapse of Crohn’s Disease (CD) occurs in 20–30% of patients at 1 year following intestinal resection, increasing by 10% per year without treatment. 1 Work by Rutgeerts’ et al . 2 within a tertiary centre supports the prac
Autor:
AW Harris, AS Dhillon
Publikováno v:
Gut. 63:A66.1-A66
Introduction Tacrolimus appears to be effective short-term treatment for patients with refractory ulcerative colitis (UC) 1 and is recommended by NICE 2 in suitable patients. We report our experience in a district general hospital out-patient setting
Publikováno v:
Europe PubMed Central
The tumor suppressor p53 exerts its antioncogenic effects in cells chiefly by regulating their progression through the cell cycle and by inducing cell death. It has been claimed that p53-transduced apoptosis involves the death receptor CD95 (Fas/APO-
Effect of a bcl-2 transgene on production and localization of precursor B cells in mouse bone marrow
Publikováno v:
Europe PubMed Central
Many B cell precursors die while differentiating in mouse bone marrow. To ascertain the mechanisms involved in this process, populations of B lineage cells and their tissue localization were analyzed in bone marrow of transgenic mice overexpressing t
Publikováno v:
Europe PubMed Central
The vav gene is expressed in all hematopoietic but few other cell types. To explore its unusual compartment-wide regulation, we cloned the murine gene, sequenced its promoter region, identified DNase I hypersensitive (HS) sites in the chromatin, and
Publikováno v:
Europe PubMed Central
B lymphocyte differentiation proceeds through a series of alternating stages of proliferative expansion interspersed with noncycling stationary phases during which cells undergo either positive selection or apoptotic cell death. The molecular control
Publikováno v:
Europe PubMed Central
Within the lymphoid compartment of mice, the Hlx homeobox gene is expressed only at early stages of B-lymphoid differentiation. To determine whether Hlx influences lymphopoiesis, transgenic mice were developed to enforce Hlx expression throughout the
Publikováno v:
Europe PubMed Central
Two primary types of TCR-alpha/beta+ T cells are found in the peripheral lymphoid system; CD4+8- T cells, with MHC-class II restricted TCR, and CD4-8+ T cells, which are MHC-class I restricted. Both lineages develop in the thymus from a series of com