Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Avrum, Spira"'
Autor:
Ana B. Pavel, Carly Garrison, Lingqi Luo, Gang Liu, Daniel Taub, Ji Xiao, Brenda Juan-Guardela, John Tedrow, Yuriy O. Alekseyev, Ivana V. Yang, Mark W. Geraci, Frank Sciurba, David A. Schwartz, Naftali Kaminski, Jennifer Beane, Avrum Spira, Marc E. Lenburg, Joshua D. Campbell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized clustering and integrative network analyses to elucidate roles for microRNAs (miRNAs) and miR
Externí odkaz:
https://doaj.org/article/3ab462eb96c1423b8efb64bcedd52c26
Autor:
Boting Ning, Andrew M. Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E. Lenburg, Jennifer E. Beane, Xaralabos Varelas
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous cell carcinoma (LUS
Externí odkaz:
https://doaj.org/article/8eeb49dcba4b46ed83d733498621d057
Autor:
Peter Mazzone, Travis Dotson, Momen M Wahidi, Michael Bernstein, Hans J Lee, David Feller Kopman, Lonny Yarmus, Duncan Whitney, Christopher Stevenson, Jianghan Qu, Marla Johnson, P Sean Walsh, Jing Huang, Lori R Lofaro, Sangeeta M Bhorade, Giulia C Kennedy, Avrum Spira, M Patricia Rivera, AEGIS Study Team, Percepta Registry Investigators
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0268567 (2022)
The Percepta Genomic Sequencing Classifier (GSC) was developed to up-classify as well as down-classify the risk of malignancy for lung lesions when bronchoscopy is non-diagnostic. We evaluated the performance of Percepta GSC in risk re-classification
Externí odkaz:
https://doaj.org/article/d2cbdc9cc15c4d2dac2dbf3f23206de8
Autor:
Gang Liu, Asaf Maoz, Christopher Stevenson, Mary E Reid, Avrum Spira, Marc E Lenburg, Joshua D Campbell, Carter Merenstein, Yusuke Koga, Austin Potter, Adam C Gower, Sherry Zhang, Hanqiao Liu, Sarah A Mazzilli, Jennifer Beane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/1a370bde366f4973b623356a8d390ced
Autor:
Ehab Billatos, Fenghai Duan, Elizabeth Moses, Helga Marques, Irene Mahon, Lindsey Dymond, Charles Apgar, Denise Aberle, George Washko, Avrum Spira, on behalf of the DECAMP investigators
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Lung cancer is the leading cause of cancer-related death due in large part to our inability to diagnose it at an early and potentially curable stage. Screening for lung cancer via low dose computed tomographic (LDCT) imaging has b
Externí odkaz:
https://doaj.org/article/27d41b02efe04290a4702a1c56677941
Autor:
Feng Xu, Naoya Tanabe, Dragos M. Vasilescu, John E. McDonough, Harvey O. Coxson, Kohei Ikezoe, Daisuke Kinose, Kevin W. Ng, Stijn E. Verleden, Wim A. Wuyts, Bart M. Vanaudenaerde, Johny Verschakelen, Joel D. Cooper, Marc E. Lenburg, Katrina B. Morshead, Alexander R. Abbas, Joseph R. Arron, Avrum Spira, Tillie-Louise Hackett, Thomas V. Colby, Christopher J. Ryerson, Raymond T. Ng, James C. Hogg
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103325- (2021)
Background: The transition from normal lung anatomy to minimal and established fibrosis is an important feature of the pathology of idiopathic pulmonary fibrosis (IPF). The purpose of this report is to examine the molecular and cellular mechanisms as
Externí odkaz:
https://doaj.org/article/26f5a885d9724d8aa67297d80c625a69
Autor:
Eric J. Burks, Jiarui Zhang, Travis B. Sullivan, Xingyi Shi, Jacob M. Sands, Shawn M. Regis, Brady J. McKee, Andrea B. McKee, Sherry Zhang, Hanqiao Liu, Gang Liu, Avrum Spira, Jennifer Beane, Marc E. Lenburg, Kimberly M. Rieger-Christ
Publikováno v:
Cancer Treatment and Research Communications, Vol 29, Iss , Pp 100486- (2021)
Introduction: Although three randomized control trials have proven mortality benefit of CT lung cancer screening (CTLS),
Externí odkaz:
https://doaj.org/article/7f40f578a6cf4273bbca14d5b6c2ced3
Autor:
Tamar Sofer, Ruitong Li, Roby Joehanes, Honghuang Lin, Adam C. Gower, Heming Wang, Nuzulul Kurniansyah, Brian E. Cade, Jiwon Lee, Stephanie Williams, Reena Mehra, Sanjay R. Patel, Stuart F. Quan, Yongmei Liu, Jerome I. Rotter, Stephen S. Rich, Avrum Spira, Daniel Levy, Sina A. Gharib, Susan Redline, Daniel J. Gottlieb
Publikováno v:
EBioMedicine, Vol 56, Iss , Pp 102803- (2020)
Background: Sleep Disordered Breathing (SDB) is associated with a wide range of pathophysiological changes due, in part, to hypoxemia during sleep. We sought to identify gene transcription associations with measures of SDB and hypoxemia during sleep,
Externí odkaz:
https://doaj.org/article/7a109d23e23847ec9146095cbbda3ada
Autor:
P. Scott Pine, Steven P. Lund, Jerod R. Parsons, Lindsay K. Vang, Ashish A. Mahabal, Luca Cinquini, Sean C. Kelly, Heather Kincaid, Daniel J. Crichton, Avrum Spira, Gang Liu, Adam C. Gower, Harvey I. Pass, Chandra Goparaju, Steven M. Dubinett, Kostyantyn Krysan, Sanford A. Stass, Debra Kukuruga, Kendall Van Keuren-Jensen, Amanda Courtright-Lim, Karol L. Thompson, Barry A. Rosenzweig, Lynn Sorbara, Sudhir Srivastava, Marc L. Salit
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background The potential utility of microRNA as biomarkers for early detection of cancer and other diseases is being investigated with genome-scale profiling of differentially expressed microRNA. Processes for measurement assurance are criti
Externí odkaz:
https://doaj.org/article/3dc1b4d4cf0f47c2b8b7f1d1e6ce5522
Autor:
Ilse M. Boudewijn, Alen Faiz, Katrina Steiling, Erica van der Wiel, Eef D. Telenga, Susan J. M. Hoonhorst, Nick H. T. ten Hacken, Corry-Anke Brandsma, Huib A. M. Kerstjens, Wim Timens, Irene H. Heijink, Marnix R. Jonker, Harold G. de Bruin, J. Sebastiaan Vroegop, Henk R. Pasma, Wim G. Boersma, Pascal Wielders, Frank van den Elshout, Khaled Mansour, Avrum Spira, Marc E. Lenburg, Victor Guryev, Dirkje S. Postma, Maarten van den Berge
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Nasal gene expression profiling is a promising method to characterize COPD non-invasively. We aimed to identify a nasal gene expression profile to distinguish COPD patients from healthy controls. We investigated whether this COPD-
Externí odkaz:
https://doaj.org/article/65ad28ccc1de4dada65462a59303ada5