Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Avram D Walts"'
Autor:
Rachel Z. Blumhagen, Jonathan S. Kurche, Carlyne D. Cool, Avram D. Walts, David Heinz, Tasha E. Fingerlin, Ivana V. Yang, David A. Schwartz
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a heterogeneous disease that is pathologically characterized by areas of normal-appearing lung parenchyma, active fibrosis (transition zones including fibroblastic foci) and dense fibrosis. D
Externí odkaz:
https://doaj.org/article/01706a12d28340c886415da719d291ac
Autor:
Mark P. Steele, Anna L. Peljto, Susan K. Mathai, Stephen Humphries, Tami J. Bang, Andrea Oh, Shawn Teague, Giuseppe Cicchetti, Christopher Sigakis, Jonathan A. Kropski, James E. Loyd, Timothy S. Blackwell, Kevin K. Brown, Marvin I. Schwarz, Rachel A. Warren, Julia Powers, Avram D. Walts, Cheryl Markin, Tasha E. Fingerlin, Ivana V. Yang, David A. Lynch, Joyce S. Lee, David A. Schwartz
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:587-593
Relatives of patients with familial interstitial pneumonia are at increased risk for pulmonary fibrosis, and develop preclinical pulmonary fibrosis (PrePF).We defined the incidence and progression of new onset PrePF; its relationship to survival amon
Autor:
Zhen Yu, Natalia I. Dmitrieva, Avram D. Walts, Hui Jin, Yangtengyu Liu, Xianfeng Ping, Elisa A. Ferrante, Lugui Qiu, Steven M. Holland, Alexandra F. Freeman, Guibin Chen, Manfred Boehm
Publikováno v:
Biology Open, Vol 9, Iss 9 (2020)
Human induced pluripotent stem cell (iPSC) technology has opened exciting opportunities for stem-cell-based therapy. However, its wide adoption is precluded by several challenges including low reprogramming efficiency and potential for malignant tran
Externí odkaz:
https://doaj.org/article/061dbdc877604a26b25c1545964aac37
Autor:
Scott M. Matson, Kevin D. Deane, Anna L. Peljto, Tami J. Bang, Peter B. Sachs, Avram D. Walts, Christopher Collora, Shuyu Ye, M. Kristen Demoruelle, Stephen M. Humphries, David A. Schwartz, Joyce S. Lee
Publikováno v:
Am J Respir Crit Care Med
Autor:
Anna L. Peljto, Rachel Z. Blumhagen, Avram D. Walts, Jonathan Cardwell, Julia Powers, Tamera J. Corte, Joanne L. Dickinson, Ian Glaspole, Yuben P. Moodley, Martina Koziar Vasakova, Elisabeth Bendstrup, Jesper R. Davidsen, Raphael Borie, Bruno Crestani, Philippe Dieude, Francesco Bonella, Ulrich Costabel, Gunnar Gudmundsson, Seamas C. Donnelly, Jim Egan, Michael T. Henry, Michael P. Keane, Marcus P. Kennedy, Cormac McCarthy, Aoife N. McElroy, Joshua A. Olaniyi, Katherine M. A. O’Reilly, Luca Richeldi, Paolo M. Leone, Venerino Poletti, Francesco Puppo, Sara Tomassetti, Valentina Luzzi, Nurdan Kokturk, Nesrin Mogulkoc, Christine A. Fiddler, Nikhil Hirani, R. Gisli Jenkins, Toby M. Maher, Philip L. Molyneaux, Helen Parfrey, Rebecca Braybrooke, Timothy S. Blackwell, Peter D. Jackson, Steven D. Nathan, Mary K. Porteous, Kevin K. Brown, Jason D. Christie, Harold R. Collard, Oliver Eickelberg, Elena E. Foster, Kevin F. Gibson, Marilyn Glassberg, Daniel J. Kass, Jonathan A. Kropski, David Lederer, Angela L. Linderholm, Jim Loyd, Susan K. Mathai, Sydney B. Montesi, Imre Noth, Justin M. Oldham, Amy J. Palmisciano, Cristina A. Reichner, Mauricio Rojas, Jesse Roman, Neil Schluger, Barry S. Shea, Jeffrey J. Swigris, Paul J. Wolters, Yingze Zhang, Cecilia M. A. Prele, Juan I. Enghelmayer, Maria Otaola, Christopher J. Ryerson, Mauricio Salinas, Martina Sterclova, Tewodros H. Gebremariam, Marjukka Myllärniemi, Roberto G. Carbone, Haruhiko Furusawa, Masaki Hirose, Yoshikazu Inoue, Yasunari Miyazaki, Ken Ohta, Shin Ohta, Tsukasa Okamoto, Dong Soon Kim, Annie Pardo, Moises Selman, Alvaro U. Aranda, Moo Suk Park, Jong Sun Park, Jin Woo Song, Maria Molina-Molina, Lurdes Planas-Cerezales, Gunilla Westergren-Thorsson, Albert V. Smith, Ani W. Manichaikul, John S. Kim, Stephen S. Rich, Elizabeth C. Oelsner, R. Graham Barr, Jerome I. Rotter, Josee Dupuis, George O’Connor, Ramachandran S. Vasan, Michael H. Cho, Edwin K. Silverman, Marvin I. Schwarz, Mark P. Steele, Joyce S. Lee, Ivana V. Yang, Tasha E. Fingerlin, David A. Schwartz
Rationale: Idiopathic pulmonary fibrosis is a rare, irreversible, and progressive disease of the lungs. Common genetic variants, in addition to non-genetic factors, have been consistently associated with IPF. Rare variants identified by candidate gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0670c24aedc8efa23979477ed15d39b
http://hdl.handle.net/10044/1/101620
http://hdl.handle.net/10044/1/101620
Autor:
Edward B. Neufeld, Katherine O'Brien, Avram D. Walts, John A. Stonik, Daniela Malide, Christian A. Combs, Alan T. Remaley
Publikováno v:
Biology, Vol 3, Iss 4, Pp 866-891 (2014)
We have previously shown that GFP-tagged human ABCG1 on the plasma membrane (PM) and in late endosomes (LE) mobilizes sterol on both sides of the membrane lipid bilayer, thereby increasing cellular cholesterol efflux to lipid surfaces. In the present
Externí odkaz:
https://doaj.org/article/5ccc75f0e42d42538bf88cedf508b95b
Autor:
Edward B. Neufeld, Katherine O'Brien, Avram D. Walts, John A. Stonik, Steven J. Demosky, Daniela Malide, Christian A. Combs, Alan T. Remaley
Publikováno v:
Biology, Vol 3, Iss 4, Pp 781-800 (2014)
We have developed a suitable heterologous cell expression system to study the localization, trafficking, and site(s) of function of the human ABCG1 transporter. Increased plasma membrane (PM) and late endosomal (LE) cholesterol generated by ABCG1 was
Externí odkaz:
https://doaj.org/article/a0d5da5cd5484533aadedc573e9665c8
Autor:
Haruhiko Furusawa, Anna L Peljto, Avram D Walts, Jonathan Cardwell, Philip L Molyneaux, Joyce S Lee, Evans R Fernández Pérez, Paul J Wolters, Ivana V Yang, David A Schwartz
Publikováno v:
Thorax
A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genet
Autor:
David A. Schwartz, H. Furusawa, Carlyne D. Cool, Ivana V. Yang, Tami J. Bang, Jonathan Cardwell, Avram D Walts, Joyce S. Lee, Paul J. Wolters, Anna L. Peljto
Publikováno v:
TP65. TP065 ENVIRONMENTAL EXPOSURES AND LUNG DISEASE.
Autor:
David A. Schwartz, Iain R. Konigsberg, Tasha E. Fingerlin, Avram D Walts, Ivana V. Yang, Jonathan Cardwell, Fabian Metzger, Mauricio Rojas, Stefanie M. Hauck, Raphael Borie
Publikováno v:
Am. J. Respir. Cell Mol. Biol. 65, 430-441 (2021)
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology
Molecular patterns and pathways in idiopathic pulmonary fibrosis (IPF) have been extensively investigated but few studies have assimilated multi-omic platforms to provide an integrative understanding of molecular patterns that are relevant in IPF. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2411b8a9e8f76479be969df23c293950
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62221
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62221