Zobrazeno 1 - 2
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pro vyhledávání: '"Avrahom Y. Sugar"'
Publikováno v:
Molecular Carcinogenesis. 26:37-43
DPC4/SMAD4 is a candidate tumor suppressor gene with a strikingly high frequency of gene alterations in pancreatic cancer that suggests a discrete role for DPC4 in these tumors. DPC4 tumor-suppressive function has been implicated to mediate the trans
Autor:
Werner Hilgers, Ralph H. Hruban, Scott E. Kern, Manu C. Shekher, David J. Tang, Avrahom Y. Sugar
Publikováno v:
Genes, Chromosomes and Cancer. 24:351-355
Chromosomal arm 1p has long been suspected, on the basis of loss of heterozygosity (LOH) and other data, to harbor a tumor suppressor gene important in pancreatic carcinomas and other tumors. We constructed a high-resolution map of LOH at I p in a pa