Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Avraham Rosenberg"'
Autor:
May E, Montasser, Cristopher V, Van Hout, Lawrence, Miloscio, Alicia D, Howard, Avraham, Rosenberg, Myrasol, Callaway, Biao, Shen, Ning, Li, Adam E, Locke, Niek, Verweij, Tanima, De, Manuel A, Ferreira, Luca A, Lotta, Aris, Baras, Thomas J, Daly, Suzanne A, Hartford, Wei, Lin, Yuan, Mao, Bin, Ye, Derek, White, Guochun, Gong, James A, Perry, Kathleen A, Ryan, Qing, Fang, Gannie, Tzoneva, Evangelos, Pefanis, Charleen, Hunt, Yajun, Tang, Lynn, Lee, Carole, Sztalryd-Woodle, Braxton D, Mitchell, Matthew, Healy, Elizabeth A, Streeten, Simeon I, Taylor, Jeffrey R, O'Connell, Aris N, Economides, Giusy, Della Gatta, Alan R, Shuldiner
Publikováno v:
Science (New York, N.Y.). 374(6572)
Increased blood levels of low-density lipoprotein cholesterol (LDL-C) and fibrinogen are independent risk factors for cardiovascular disease. We identified associations between an Amish-enriched missense variant (p.Asn352Ser) in a functional domain o
Autor:
Avraham Rosenberg, Irving W. Wainer, Lukasz Ciesla, M. Okine, Ruin Moaddel, Lawrence Toll, Katina Sourou Sylvestre Dossou
The α3β4α5 nAChR has been recently shown to be a useful target for smoking cessation pharmacotherapies. Herein, we report on the development and characterization of the α3β4α5 nicotinic receptor column by frontal displacement chromatography. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee31dc039046105d6697645337f879c4
https://europepmc.org/articles/PMC4748418/
https://europepmc.org/articles/PMC4748418/
Autor:
A. Brizzi, Irving W. Wainer, Claudia Mugnaini, S. Nocerino, Avraham Rosenberg, Kevin Spelman, J. Frazier, Charles J. Frazier, Ruin Moaddel
Publikováno v:
Analytical Biochemistry. 412:85-91
Cannabinoid receptors, CB1 and CB2, are therapeutic targets in the treatment of anxiety, obesity, movement disorders, glaucoma, and pain. We have developed an on-line screening method for CB1 and CB2 ligands, where cellular membrane fragments of a ch
Autor:
Dominik Feuerbach, Avraham Rosenberg, Ruin Moaddel, Katarzyna M. Targowska-Duda, Xiao Juan Yuan, Irving W. Wainer, Hugo R. Arias, Krzysztof Jozwiak
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 42:1525-1535
The interaction of ibogaine and phencyclidine (PCP) with human (h) alpha3beta4-nicotinic acetylcholine receptors (AChRs) in different conformational states was determined by functional and structural approaches including, radioligand binding assays,
Autor:
Kun Yan, Jennifer E. Van Eyk, David M. Herrington, Avraham Rosenberg, Allen D. Everett, Zhicheng Jin, Richard S. Vander Heide, Zongming Fu, Grace Athas, Timothy D. Howard, Barbara J. Crain
Evaluate combination of heat and elevated pressure to enhance protein extraction and quality of formalin-fixed (FF), and FF paraffin-embedded (FFPE) aorta for proteomics.Proteins were extracted from fresh frozen aorta at room temperature (RT). FF and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c855ce01fec2d18bfb2c81048b571620
https://europepmc.org/articles/PMC4340701/
https://europepmc.org/articles/PMC4340701/
Autor:
Thao Tran, Avraham Rosenberg, Carlos A. Zarate, Irving W. Wainer, Lucita Jimenez, Yingxian Xiao, Joanna Kozak, Galia Abdrakhmanova, Lawrence Toll, Ruin Moaddel, Krzysztof Jozwiak
Publikováno v:
European journal of pharmacology. 698(1-3)
The effect of the (R,S)-ketamine metabolites (R,S)-norketamine, (R,S)-dehydronorketamine, (2S,6S)-hydroxynorketamine and (2R,6R)-hydroxynorketamine on the activity of α7 and α3β4 neuronal nicotinic acetylcholine receptors was investigated using pa
Autor:
Livio Luongo, Roger G. Pertwee, Ruin Moaddel, Daniele Bolognini, Maria Grazia Cascio, Stefania Dragoni, Luca Bellucci, Alessia Ligresti, Maria De Chiaro, Massimo Valoti, Sabatino Maione, Federico Corelli, Stefania Nocerino, Claudia Mugnaini, Andrea Tafi, Avraham Rosenberg, Serena Pasquini, Vincenzo Di Marzo, Francesca Guida, Valentina Pedani
Publikováno v:
ChemMedChem. 7(5)
Three heterocyclic systems were selected as potential bioisosteres of the amide linker for a series of 1,6-disubstituted-4-quinolone-3-carboxamides, which are potent and selective CB2 ligands that exhibit poor water solubility, with the aim of improv
Autor:
Hugo R. Arias, Dominik Feuerbach, Ruin Moaddel, Krzysztof Jozwiak, Katarzyna M. Targowska-Duda, Doug E Blaty, Avraham Rosenberg, Irving W. Wainer
Publikováno v:
The FASEB Journal. 24
The interaction of tricyclic antidepressants (TCAs) with human (h)α4β2 nicotinic receptors (AChRs) was compared to that for mecamylamine. The results established that: (a) [3H]imipramine binds to h...
Autor:
Irving W. Wainer, Dominik Feuerbach, Avraham Rosenberg, Ruin Moaddel, Katarzyna M. Targowska-Duda, Hugo R. Arias, Krzysztof Jozwiak
The interaction of tricyclic antidepressants with the human (h) alpha4beta2 nicotinic acetylcholine receptor in different conformational states was compared with that for the noncompetitive antagonist mecamylamine by using functional and structural a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8ced1b8d03b1cfc1c9f4f6a230572d
https://europepmc.org/articles/PMC4605392/
https://europepmc.org/articles/PMC4605392/
Autor:
Cecilia Bouzat, Dominik Feuerbach, Fernanda Gumilar, Hugo R. Arias, Katarzyna M. Targowska-Duda, Avraham Rosenberg, Krzysztof Jozwiak, Irving W. Wainer, Ruin Moaddel
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
To characterize the binding sites and the mechanisms of inhibition of bupropion on muscle-type nicotinic acetylcholine receptors (AChRs), structural and functional approaches were used. The results established that bupropion: (a) inhibits epibatidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9e92ca9b1b741e5ec33b84bddfa5f8
https://pubs.acs.org/doi/abs/10.1021/bi802206k
https://pubs.acs.org/doi/abs/10.1021/bi802206k