Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Avraham Ben-Nun"'
Autor:
Florian Wanke, Sonja Moos, Andrew L. Croxford, André P. Heinen, Stephanie Gräf, Bettina Kalt, Denise Tischner, Juan Zhang, Isabelle Christen, Julia Bruttger, Nir Yogev, Yilang Tang, Morad Zayoud, Nicole Israel, Khalad Karram, Sonja Reißig, Sonja M. Lacher, Christian Reichhold, Ilgiz A. Mufazalov, Avraham Ben-Nun, Tanja Kuhlmann, Nina Wettschureck, Andreas W. Sailer, Klaus Rajewsky, Stefano Casola, Ari Waisman, Florian C. Kurschus
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1270-1284 (2017)
Arrival of encephalitogenic T cells at inflammatory foci represents a critical step in development of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. EBI2 and its ligand, 7α,25-OHC, direct immune cell locali
Externí odkaz:
https://doaj.org/article/4430b96b5b16407db24119db388b3fa8
Autor:
Nathali Kaushansky, Nicole Kerlero de Rosbo, Rina Zilkha-Falb, Reut Yosef-Hemo, Lydia Cohen, Avraham Ben-Nun
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27860 (2011)
Antigen-induced peripheral tolerance is potentially one of the most efficient and specific therapeutic approaches for autoimmune diseases. Although highly effective in animal models, antigen-based strategies have not yet been translated into practica
Externí odkaz:
https://doaj.org/article/00795982210e47bf8acafe07cf0e27fd
Autor:
Klaus Rajewsky, Nina Wettschureck, Stephanie Gräf, Ilgiz A. Mufazalov, Morad Zayoud, Tanja Kuhlmann, Sonja Moos, Denise Tischner, Yilang Tang, Florian C. Kurschus, Andreas W. Sailer, Nir Yogev, Andrew L. Croxford, Avraham Ben-Nun, Julia Bruttger, Bettina Kalt, Sonja M. Lacher, Ari Waisman, Isabelle Christen, Sonja Reißig, André P. Heinen, Khalad Karram, Christian Reichhold, Florian Wanke, Stefano Casola, Nicole Israel, Juan Zhang
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1270-1284 (2017)
Arrival of encephalitogenic T cells at inflammatory foci represents a critical step in development of experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. EBI2 and its ligand, 7{alpha},25-OHC, direct immune cell l
Publikováno v:
Stem Cell Reports
Summary The subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus are known as neurogenic niches. We show that the median eminence (ME) of the hypothalamus comprises BrdU+ newly pro
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 203(7)
Multiple sclerosis is an inflammatory disease of the CNS characterized by neurologic impairment resulting from primary demyelination and axonal damage. The pathogenic mechanisms of disease development include Ag-specific T cell activation and Th1 dif
Autor:
Bjarke E. Hansen, Ron Milo, Avraham Ben-Nun, Miriam Eisenstein, Daniel M. Altmann, Claus Henrik Nielsen, Gabriel Zeilig, Nathali Kaushansky, Sigalit Boura-Halfon, Hans Lassmann
Publikováno v:
Journal of Biological Chemistry. 290:15260-15278
Gene-wide association and candidate gene studies indicate that the greatest effect on multiple sclerosis (MS) risk is driven by the HLA-DRB1*15:01 allele within the HLA-DR15 haplotype (HLA-DRB1*15:01-DQA1*01:02-DQB1*0602-DRB5*01:01). Nevertheless, li
Autor:
Reinhard Hohlfeld, Avraham Ben-Nun, Nathali Kaushansky, Roland S. Liblau, Kerstin Berer, Naoto Kawakami, Gurumoorthy Krishnamoorthy, Hartmut Wekerle
Publikováno v:
Journal of Autoimmunity. 54:33-50
Multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS), presents as a complex disease with variable clinical and pathological manifestations, involving different pathogenic pathways. Animal models, particularly experimen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(9)
Autor:
Lennart T. Mars, Jean-Charles Guéry, Abdulraouf Ramadan, Miriam Eisenstein, Roland S. Liblau, Liliana E. Lucca, Phuong Nguyen, Alessandro Sette, Nadège Carrié, Avraham Ben-Nun, Sabine Desbois, Terrence L. Geiger
Publikováno v:
The Journal of Immunology. 193:3267-3277
The recognition of multiple ligands by a single TCR is an intrinsic feature of T cell biology, with important consequences for physiological and pathological processes. Polyspecific T cells targeting distinct self-antigens have been identified in hea
Publikováno v:
Journal of Biological Chemistry. 288:32852-32860
An immunosuppressive motif was recently found within the HIV-1 gp41 fusion protein (termed immunosuppressive loop-associated determinant core motif (ISLAD CM)). Peptides containing the motif interact with the T-cell receptor (TCR) complex; however, t