Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Avner Yayon"'
Autor:
Katja Thümmler, Eran Rom, Thomas Zeis, Maren Lindner, Sarah Brunner, John J. Cole, Diana Arseni, Steve Mücklisch, Julia M. Edgar, Nicole Schaeren-Wiemers, Avner Yayon, Christopher Linington
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple sclerosis, but targeting this therapeutically is complicated by its functional pleiotropy. We now identify FGF2 as a factor up-regulated by astrocyt
Externí odkaz:
https://doaj.org/article/7ee1fa64b1394a10aeb801926f69e36f
Autor:
Mun-Ik Lee, Jun-Hyung Kim, Ho-Hyun Kwak, Heung-Myong Woo, Jeong-Hee Han, Avner Yayon, Yun-Chan Jung, Jin-Man Cho, Byung-Jae Kang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-12 (2019)
Abstract Background The objective of this study was to assess the efficacy of intra-articular injections of hyaluronic acid (HA) and a novel, on-site conjugate of HA with autologous fibrinogen in platelet-rich plasma (HA-PRP) in a canine model of ost
Externí odkaz:
https://doaj.org/article/008960d4705f430b977d9d9eee7f94b1
Autor:
Leonid Kandel, Gabriel Agar, Ori Elkayam, Aybek Sharipov, Omer Slevin, Gurion Rivkin, Moshe Dahan, Valerie Aloush, Amos B. Pyeser, Yaron Brin, Yiftah Beer, Avner Yayon
Publikováno v:
Heliyon, Vol 6, Iss 7, Pp e04475- (2020)
Objective: Osteoarthritis (OA) is a widespread degenerative joint disease leading to progressive loss of function and pain. Available treatments do not provide long-term relief or improvement. This study aimed to assess the safety and efficacy of a n
Externí odkaz:
https://doaj.org/article/67a803c71ab74ed68ff8e1c2f3bb3fed
Publikováno v:
Polymers, Vol 12, Iss 8, p 1754 (2020)
Cell migration has a central role in osteochondral defect repair initiation and biomaterial-mediated regeneration. New advancements to reestablish tissue function include biomaterials and factors promoting cell recruitment, differentiation and tissue
Externí odkaz:
https://doaj.org/article/f40c1d6736824c21bcd62882353c1ce1
Autor:
Sonja Häckel, Mona Zolfaghar, Jie Du, Sven Hoppe, Lorin M. Benneker, Nathalie Garstka, Marianna Peroglio, Mauro Alini, Sibylle Grad, Avner Yayon, Zhen Li
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5036 (2019)
We investigated the effects of a fibrin-hyaluronic acid hydrogel (FBG−HA) and fibroblast growth factor 18 (FGF-18) for nucleus pulposus (NP) regeneration. Healthy bovine (n = 4) and human degenerated NP cells (n = 4) were cultured for 14 days in FB
Externí odkaz:
https://doaj.org/article/e3768759fb3a48a08d31a6d53f2af8e4
Publikováno v:
Cell Transplantation, Vol 7 (1998)
Ample experimental examples have been accumulated during the last 3 decades indicating the ability of exogenous sources of cultured cells to serve as implants accelerating cartilage regeneration in defects of articular surfaces. In some cases, the re
Externí odkaz:
https://doaj.org/article/692000138bd04bf2a5706311ef43f5aa
Autor:
Avner Yayon, Sibylle Grad, Nicole Kops, Andrea Lolli, M.L. Vainieri, Domenico D'Atri, G.J.V.M. van Osch, Kavitha Sivasubramaniyan, Mauro Alini, David Eglin
Publikováno v:
Acta Biomaterialia, 101, 293-303. Elsevier
Acta Biomater
Acta Biomater
Biomaterials play a pivotal role in cell-free cartilage repair approaches, where cells must migrate through the scaffold, fill the defect, and then proliferate and differentiate facilitating tissue remodeling. Here we used multiple assays to test the
Autor:
Gerjo J.V.M. van Osch, M.L. Vainieri, Kavitha Sivasubramaniyan, Andrea Lolli, Jacopo Oieni, Avner Yayon, Nicole Kops
Publikováno v:
Journal of Controlled Release, 309, 220-230. Elsevier
Articular cartilage is frequently injured by trauma or osteoarthritis, with limited and inadequate treatment options. We investigated a new strategy based on hydrogel-mediated delivery of a locked nucleic acid microRNA inhibitor targeting miR-221 (an
Autor:
Jacopo Oieni, Gerjo J.V.M. van Osch, Nicole Kops, Marcelle Machluf, Avner Yayon, Domenico D'Atri, Andrea Lolli
Publikováno v:
J control release
Journal of Controlled Release, 333, 28-40. Elsevier
Journal of Controlled Release: official journal of the Controlled Release Society, 333
Journal of Controlled Release, 333, 28-40. Elsevier
Journal of Controlled Release: official journal of the Controlled Release Society, 333
Antisense oligonucleotides (ASOs) carry an enormous therapeutic potential in different research areas, however, the lack of appropriate carriers for their delivery to the target tissues is hampering their clinical translation. The present study inves
Autor:
Valerie Aloush, Yiftah Beer, Avner Yayon, Aybek Sharipov, Moshe Dahan, Gurion Rivkin, Gabriel Agar, Yaron S. Brin, Ori Elkayam, Leonid Kandel, Omer Slevin, Amos B. Pyeser
Publikováno v:
Heliyon, Vol 6, Iss 7, Pp e04475-(2020)
Heliyon
Heliyon
Objective Osteoarthritis (OA) is a widespread degenerative joint disease leading to progressive loss of function and pain. Available treatments do not provide long-term relief or improvement. This study aimed to assess the safety and efficacy of a no