Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor.

Autor: Goolam MA; School of Molecular Bioscience, University of Sydney, NSW 2006, Australia., Ward JH; School of Molecular Bioscience, University of Sydney, NSW 2006, Australia., Avlani VA; School of Molecular Bioscience, University of Sydney, NSW 2006, Australia., Leach K; Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria 3052, Australia., Christopoulos A; Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria 3052, Australia., Conigrave AD; School of Molecular Bioscience, University of Sydney, NSW 2006, Australia. Electronic address: arthur.conigrave@sydney.edu.au.

Publikováno v: FEBS letters [FEBS Lett] 2014 Sep 17; Vol. 588 (18), pp. 3340-6. Date of Electronic Publication: 2014 Jul 28.

Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides: inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids.

Autor: Broadhead GK; School of Molecular Bioscience, University of Sydney, New South Wales 2006, Australia., Mun HC, Avlani VA, Jourdon O, Church WB, Christopoulos A, Delbridge L, Conigrave AD

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2011 Mar 18; Vol. 286 (11), pp. 8786-97. Date of Electronic Publication: 2010 Dec 27.

The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.

Autor: Avlani VA; Drug Discovery Biology Laboratory, Department of Pharmacology, Monash University, Clayton, Victoria, Australia., McLoughlin DJ, Sexton PM, Christopoulos A

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2008 Jun; Vol. 325 (3), pp. 927-34. Date of Electronic Publication: 2008 Mar 05.

Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands.

Autor: Avlani VA; Drug Discovery Biology Laboratory, Department of Pharmacology, Monash University, Clayton, 3800 Australia., Gregory KJ, Morton CJ, Parker MW, Sexton PM, Christopoulos A

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2007 Aug 31; Vol. 282 (35), pp. 25677-86. Date of Electronic Publication: 2007 Jun 25.