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Akademický článek

The aberrant asynchronous replication — characterizing lymphocytes of cancer patients — is erased following stem cell transplantation

Autor: Korenstein-Ilan Avital, Mashevich Maya, Cytron Samuel, Nagler Arnon, Avivi Lydia

Publikováno v: BMC Cancer, Vol 10, Iss 1, p 230 (2010)

Abstract Background Aberrations of allelic replication timing are epigenetic markers observed in peripheral blood cells of cancer patients. The aberrant markers are non-cancer-type-specific and are accompanied by increased levels of sporadic aneuploi

Externí odkaz: https://doaj.org/article/1cb6d808c78b4bffb7da798e73513ce2

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Akademický článek

Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA

Autor: Freedman Jane, Rimon Ayelet, Amir Itay, Yeshaya Josepha, Shohat Mordechai, Avivi Lydia

Publikováno v: Molecular Cytogenetics, Vol 2, Iss 1, p 11 (2009)

Abstract Background The temporal order of allelic replication is interrelated to the epigenomic profile. A significant epigenetic marker is the asynchronous replication of monoallelically-expressed genes versus the synchronous replication of bialleli

Externí odkaz: https://doaj.org/article/a48b2ba24bed4a6880ea9fb377161baf

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Akademický článek

Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients

Autor: Ramon Jacob, Dotan Aviva, Dotan Zohar A, Avivi Lydia

Publikováno v: BMC Cancer, Vol 8, Iss 1, p 390 (2008)

Abstract Background Allelic counterparts of biallelically expressed genes display an epigenetic symmetry normally manifested by synchronous replication, different from genes subjected to monoallelic expression, which normally are characterized by an

Externí odkaz: https://doaj.org/article/794537ebf7e744f4acc2089775275f12

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