Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia

Autor: Michiel Coesmans, Najaf Amin, Christian G. Bouwkamp, Aviva Nijburg, Timothy Wu, Maarouf Baghdadi, H. Berna Beverloo, Nilhan Gunhanlar, Guido J. Breedveld, Bas Lendemeijer, Veerle Bergink, P. Roberto Bakker, Carolyn D. Langen, Edwin Mientjes, Witte J.G. Hoogendijk, Ype Elgersma, Frans W. Verheijen, A.T. Spijker, André G. Uitterlinden, Simone Olgiati, Femke M.S. de Vrij, M. Arfan Ikram, Ton de Wit, Vincenzo Bonifati, Henning Tiemeier, Loes M. Olde Loohuis, Dan Cohen, Cornelia M. van Duijn, Rob M. Kok, Guy Shpak, Mehrnaz Ghazvini, Tonya White, P. M. Judith Haffmans, Meike W. Vernooij, Tracy Li, Erik Hoencamp, Marialuisa Quadri, Albert Hofman, Ben Distel, Joost Gribnau, Shreekara Gopalakrishna, Steven A. Kushner, Jacob A. S. Vorstman

Publikováno v: Molecular Psychiatry, 24(5), 757-771. Nature Publishing Group
Molecular psychiatry, 24, 757-771. Nature Publishing Group
Molecular Psychiatry

Schizophrenia is highly heritable, yet its underlying pathophysiology remains largely unknown. Among the most well-replicated findings in neurobiological studies of schizophrenia are deficits in myelination and white matter integrity; however, direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47c11de95e90cc589d840a6752d3ce2
https://pure.eur.nl/en/publications/995aa584-ec6f-4e06-81d1-54836f7e439e