Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aviva Gamliel-Lazarovich"'
Publikováno v:
Rambam Maimonides Medical Journal, Vol 4, Iss 2, p e0008 (2013)
Cardiovascular disease (CVD), associated with vascular atherosclerosis, is the major cause of death in Western societies. Current risk estimation tools, such as Framingham Risk Score (FRS), based on evaluation of multiple standard risk factors, are l
Externí odkaz:
https://doaj.org/article/e3a7f002e4694761a20d541b2602ed9a
Autor:
Hanan Abu-Tayeh Suleiman, Shereen Said, Haya Ali Saleh, Aviva Gamliel-Lazarovich, Eyas Haddad, Irina Minkov, Yaniv Zohar, Neta Ilan, Israel Vlodavsky, Zaid Abassi, Suheir Assady
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12691
The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney inju
Publikováno v:
Journal of Cardiovascular Pharmacology. 60:508-512
The beneficial effects of eplerenone, a specific mineralocorticoid receptor blocker, were previously demonstrated in early atherosclerosis (ATS). The aim of the present study was to evaluate the effect of eplerenone in advanced versus early ATS. Apol
Publikováno v:
Cardiovascular Research. 73:463-469
Angiotensin II (Ang II), a bioactive peptide of the renin-angiotensin system (RAAS), plays an important role in the development of cardiovascular diseases (CVD). Pharmacological inhibition of angiotensin-converting enzyme (ACE), the Ang II forming en
Publikováno v:
Nephrology Dialysis Transplantation. 22:597-601
Background. Hypertension is a major risk factor for cardiovascular disease and the renin– angiotensin–aldosterone system (RAAS) plays a central pathophysiological role in its formation. Angiotensin-converting enzyme (ACE) and its homologue ACE2 c
Publikováno v:
Atherosclerosis. 237(1)
Objective: The liver is the central organ of fatty acid and triglyceride metabolism. Oxidation and synthesis of fatty acids and triglycerides is under the control of peroxisome-proliferator-activated receptors (PPAR) a. Impairment of these receptors'
Publikováno v:
European journal of gastroenterologyhepatology. 25(9)
OBJECTIVE Obesity, diabetes, fatty liver, and hypertension are major determinants of the metabolic syndrome. The effects of aldosterone and mineralocorticoid receptor blockers on fatty liver are largely unknown. The aim of the present study was to ev
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 15 (2014)
Introduction: A low-sodium diet (LSD) was shown to increase both angiotensin II (AngII) and aldosterone levels, and to accelerate atherosclerosis in apolipoprotein E-deficient (E0) mice. The aim of the present study was to examine whether accelerated
Autor:
Aviva Gamliel-Lazarovich, Shlomo Keidar, Hagai Tavori, Michael Aviram, Soliman Khatib, Zaid Abassi, Jacob Vaya
Publikováno v:
Atherosclerosis. 222(1)
Aim Serum paraoxonase 1 (PON1) is an HDL-associated lipolactonase and its association with hypertension is controversial. We studied the possible role of PON1 in blood pressure (BP) regulation, by using PON1 knockout (PON1KO) mice. Methods and result
Autor:
Maayan Shiner, Anna Gantman, Michael Aviram, Shlomo Keidar, Aviva Gamliel-Lazarovich, Raymond Coleman
Publikováno v:
Atherosclerosis. 211(1)
Objective Selective uptake of high density lipoprotein (HDL) cholesteryl ester (CE) is considered as the major source of cholesterol for production of steroids in the adrenal gland in rodents. As paraoxonase 1 (PON1) is an HDL-associated lipo-lactona