Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Aviv Gazit"'
Autor:
Aviv Gazit, James Y. Becker
Publikováno v:
Electrochemical Science Advances, Vol 3, Iss 5, Pp n/a-n/a (2023)
Abstract The present article is fully confined to cyclic voltammetric measurements of a series of bridged and non‐bridged annulenediones (quinones of large conjugated rings of aromatic character). The evaluation of their electrochemical redox prope
Externí odkaz:
https://doaj.org/article/ac9f4eda449c4ffa97643102716a2c44
Autor:
Aviv Gazit, James Y. Becker
Publikováno v:
Electrochemical Science Advances.
Publikováno v:
EMBO Molecular Medicine
Telomerase is expressed in the neonatal brain, in distinct regions of adult brain, and was shown to protect developing neurons from apoptosis. Telomerase reactivation by gene manipulation reverses neurodegeneration in aged telomerase-deficient mice.
Publikováno v:
Endothelium. 13:51-59
Angiogenesis, the formation of new blood vessels, is tightly regulated by growth factors, such as vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF). The authors hypothesize that nerve growth factor (NGF), a well known neuro
Autor:
Ilia Fishbein, Galila Lazarovich, Shmuel Banai, Alexander Levitzki, Louise S. Perez, Aviv Gazit, Michael Chorny, Jianchuan Gao, S. David Gertz, Gershon Golomb
Publikováno v:
Biomaterials. 26:4898-4901
Erratum to ‘Locally delivered nanoencapsulated tyrphostin (AGL-2043) reduces neointima formation in balloon-injured rat carotid and stented porcine coronary arteries’ [Biomaterials 26 (2005) 451–461] Shmuel Banai, Michael Chorny, S. David Gertz
Autor:
Ilia Fishbein, Aviv Gazit, Alexander Levitzki, Shmuel Banai, Louise S. Perez, Galila Lazarovichi, Gershon Golomb, Michael Chorny, S. David Gertz, Jianchuan Gao
Publikováno v:
Biomaterials. 26:451-461
Local delivery of antiproliferative drugs encapsulated in biodegradable nanoparticles (NP) has shown promise as an experimental strategy for preventing restenosis development. A novel PDGFRbeta-specific tyrphostin, AGL-2043, was formulated in polylac
Autor:
Hong S. He, Hiroshi Maruta, Yoshihiro Yamashita, Alexander Levitzki, Guillaume Lessene, Jonathan B. Baell, Kawakami, Hsing Jien Kung, Yuko Kawakami, Yumiko Hirokawa, Hiroyuki Mano, Aviv Gazit, Ching Yi Hsieh
Publikováno v:
Cancer Biology & Therapy. 3:96-101
AG 879 has been widely used as a Tyr kinase inhibitor specific for ErbB2 and FLK-1, a VEGF receptor. The IC(50) for both ErbB2 and FLK-1 is around 1 microM. AG 879, in combination of PP1 (an inhibitor specific for Src kinase family), suppresses almos
Publikováno v:
Journal of Biological Chemistry. 278:40442-40454
Because insulin-like growth factor-1 (IGF-1) and its receptor play a pivotal role in many cancers, it is an attractive target for the design of inhibitors. Here we present a new family of bioisostere inhibitors, based on the structure of AG 538. AG 5
Publikováno v:
FEBS Letters. 537:47-52
Glutathione-S-transferase (GST)-pp60c-Src (GST-Src) expressed in Escherichia coli is as catalytically active as purified, activated pp60c-Src protein derived from human platelets. We utilized the bacterially expressed enzyme, together with informatio
Autor:
Alexander Levitzki, Rubina Levitzki, Aviv Gazit, Zipora Shlomai, Hannah Ben-Bassat, Zipora Hartzstark, Benjamin Y. Klein
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:163-171
Non-Hodgkin lymphomas usually become resistant to chemotherapy and relapse due to the their intense antiapoptotic robustness. Furthermore, the slow growth of these malignancies limits the effectiveness of drugs aimed mainly at the proliferative pathw