Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Avital Mendelson"'
Autor:
Yunfeng Liu, Shan Su, Sarah Shayo, Weili Bao, Mouli Pal, Kai Dou, Patricia A. Shi, Banu Aygun, Sally Campbell-Lee, Cheryl A. Lobo, Avital Mendelson, Xiuli An, Deepa Manwani, Hui Zhong, Karina Yazdanbakhsh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by painful vaso-occlusive crises (VOC) and chronic hemolysis. The mononuclear phagocyte system is pivotal to SCD pathophysiology, but the mechanisms governing monocyte/macrophag
Externí odkaz:
https://doaj.org/article/93a992862e794a0f98877ac118afd2c6
Publikováno v:
HemaSphere, Vol 3, Iss 6, p e299 (2019)
Externí odkaz:
https://doaj.org/article/b3d5883002f14d46a6cb9e004d6aad32
Autor:
Divya Beri, Manpreet Singh, Marilis Rodriguez, Mihaela Barbu-Stevanovic, Giselle Rasquinha, Avital Mendelson, Xiuli An, Deepa Manwani, Karina Yazdanbakhsh, Cheryl A. Lobo
Publikováno v:
Blood Advances. 7:649-663
Sickle red blood cells (RBCs) represent a naturally existing host-cell resistance mechanism to hemoparasite infections. We investigate the basis of this resistance using Babesia divergens grown in sickle (SS) and sickle trait (AS) cells. We found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e38c17008efac8a72b1f79734dcd1d
https://doi.org/10.1182/bloodadvances.2022008159
https://doi.org/10.1182/bloodadvances.2022008159
Autor:
Mahmudur Rahman, Yunfeng Liu, Alice Tang, Avital Mendelson, David Shi, Helen Zhang, Patricia A. Shi, Karina Yazdanbakhsh, Weili Bao, Xiuli An, Ana Nicolle Strat, Deepa Manwani
Publikováno v:
Blood. 138:2570-2582
Sickle cell disease (SCD) is characterized by hemolytic anemia, which can trigger oxidative stress, inflammation, and tissue injury that contribute to disease complications. Bone marrow mesenchymal stromal cells (MSCs) tightly regulate hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62624ed662808c5b9de81d5dd37ecd52
https://doi.org/10.1182/blood.2021012663
https://doi.org/10.1182/blood.2021012663
Autor:
Avital Mendelson, Alice Tang
Publikováno v:
Curr Opin Hematol
Purpose of review Platelet transfusion can be life-saving but carries a risk of infection or alloimmunization and is limited by insufficient donor sources and restricted unit shelf life. Generating sufficient platelets in vitro to replace a unit of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085a3b8880e5975a7ff12024e1ea0b24
https://europepmc.org/articles/PMC8490274/
https://europepmc.org/articles/PMC8490274/
Autor:
Shijie Zhang, Shihui Wang, Patrick G. Gallagher, Xiuli An, Avital Mendelson, Yaomei Wang, Jing Liu, Yongshuai Han, Xianfang Wu, Karina Yazdanbakhsh, Xinhua Guo, Gang Huang, Charles M. Rice, Wei Li, Yumin Huang, Yuanlin Xu, Huizhi Zhao, Huan Zhang, Lixiang Chen
Publikováno v:
Blood
The erythroblastic island (EBI), composed of a central macrophage and surrounding erythroid cells, was the first hematopoietic niche discovered. The identity of EBI macrophages has thus far remained elusive. Given that Epo is essential for erythropoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e7fcc950babd882081c385405395b
https://doi.org/10.1182/blood.2019000430
https://doi.org/10.1182/blood.2019000430
Autor:
Wei Li, Avital Mendelson, Yongshuai Han, Shihui Wang, Shijie Zhang, Linlin Zhang, Xiaoli Qu, Donghao Liu, Chengjie Gao, Jingyu Geng, Lixiang Chen, Huan Zhang, Karina Yazdanbakhsh, Xiuli An, Xinhua Guo
Publikováno v:
Blood
The erythropoietin receptor (EpoR) has traditionally been thought of as an erythroid-specific gene. Notably, accumulating evidence suggests that EpoR is expressed well beyond erythroid cells. However, the expression of EpoR in non-erythroid cells has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bbfb2911d24ce4e4271dcda35b1cb4
https://pubmed.ncbi.nlm.nih.gov/34098576
https://pubmed.ncbi.nlm.nih.gov/34098576
Publikováno v:
HemaSphere
HemaSphere, Vol 3, Iss 6, p e299 (2019)
HemaSphere, Vol 3, Iss 6, p e299 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08e165b8fa2effccc8844fd3637d252
http://europepmc.org/articles/PMC6924564
http://europepmc.org/articles/PMC6924564
Autor:
Ana Nicolle Strat, Avital Mendelson, Sophie Ohrn, Karina Yazdanbakhsh, Cheryl A. Lobo, Peter Rosston, Xiuli An, Georgia Fallon, Hui Zhong, Weili Bao
Publikováno v:
JCI Insight. 4
The complex process of platelet formation originates with the hematopoietic stem cell, which differentiates through the myeloid lineage, matures, and releases proplatelets into the BM sinusoids. How formed platelets maintain a low basal activation st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559e06b319ad6f90d445a0ae166ca688
https://doi.org/10.1172/jci.insight.126982
https://doi.org/10.1172/jci.insight.126982
Publikováno v:
Transfus Clin Biol
Patients with sickle cell disease (SCD) suffer from intravascular hemolysis associated with vascular injury and dysfunction. Painful vaso-occlusive crisis (VOC) involving increased attachment of sickle erythrocytes and activated leukocytes to damaged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc79ff7b2cb64482eea3a22153c33a02
https://europepmc.org/articles/PMC6488014/
https://europepmc.org/articles/PMC6488014/