Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Avital Hay-Koren"'
Autor:
Andreas Goutopoulos, Iris Amanati, Ali Fattaey, Avital Hay-Koren, Philippe Nakache, Omri Erez, Dimitri Kovalerchik, Dikla Paz, Simone Botti, Hannah Oppenheimer, Irit Fainer
Publikováno v:
Cancer Research. 82:2326-2326
ACSS2 is a nucleo-cytoplasmic enzyme that converts acetate into Acetyl-CoA. In many tumor types ACSS2 is dramatically upregulated in response to the hypoxic and lipid-depleted conditions often encountered in the tumor microenvironment. In these condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27666ec2f6a18838289692f2c7e8af4
https://doi.org/10.1158/1538-7445.am2022-2326
https://doi.org/10.1158/1538-7445.am2022-2326
Autor:
Andreas Goutopoulos, Iris Amanati, Avital Hay-Koren, Ali Fattaey, Philippe Nakache, Dimitri Kovalerchik, Dikla Paz, Simone Botti, Hanna Oppenheimer, Omri Erez, Irit Fainer
Publikováno v:
Cancer Research. 82:1397-1397
The Methylthioadenosine phosphorylase (MTAP) gene is in chromosome 9q21 location, which includes p16/CDKNA and is homozygously deleted in about 15% of all cancers, including a large proportion of gliomas, mesotheliomas and T cell lymphomas. MTAP clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68caa53e8015ae9b1ac4a6f29e332a28
https://doi.org/10.1158/1538-7445.am2022-1397
https://doi.org/10.1158/1538-7445.am2022-1397
Autor:
Dikla Paz, Inbal Mor, Iris Alchanati, Simone Botti, Nina Pastukh, Omri Erez, Philippe Nakache, Eyal Gottlieb, Andreas Goutopoulos, Avital Hay-Koren, Dimitri Kovalerchik, Hannah Oppenheimer
Publikováno v:
Cancer Research. 80:LB-295
Under the low oxygen and lipid-depleted conditions, often encountered in the tumor microenvironment, acetate is used as nutrient by cancer cells for the biosynthesis of fatty acids. ACSS2, the enzyme responsible for acetate capture within the cell an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abae9a35ee4949c0089287da408d2fb6
https://doi.org/10.1158/1538-7445.am2020-lb-295
https://doi.org/10.1158/1538-7445.am2020-lb-295
Publikováno v:
Molecular Biology of the Cell
The effector protein of the canonical Wnt pathway is β-catenin, which is regulated by the ubiquitin system. This study shows that the E3 ubiquitin ligase EDD ubiquitinates β-catenin, leading to up-regulation of β-catenin's expression levels and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf38dbadf78f20adedd1648c7361b25
https://doi.org/10.1091/mbc.e10-05-0440
https://doi.org/10.1091/mbc.e10-05-0440