Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Avital A Rodal"'
Autor:
Steven J Del Signore, Sarah A Biber, Katherine S Lehmann, Stephanie R Heimler, Benjamin H Rosenfeld, Tania L Eskin, Sean T Sweeney, Avital A Rodal
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007052 (2017)
Lowe Syndrome is a developmental disorder characterized by eye, kidney, and neurological pathologies, and is caused by mutations in the phosphatidylinositol-5-phosphatase OCRL. OCRL plays diverse roles in endocytic and endolysosomal trafficking, cyto
Externí odkaz:
https://doaj.org/article/21e27e9cff2148718c0042df96763c68
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003450 (2013)
The formation of synapses and the proper construction of neural circuits depend on signaling pathways that regulate cytoskeletal structure and dynamics. After the mutual recognition of a growing axon and its target, multiple signaling pathways are ac
Externí odkaz:
https://doaj.org/article/e0b0273f00634eaab4752ad3dfa27d0a
Publikováno v:
Molecular Biology of the Cell. 34
Following exocytosis at active zones, synaptic vesicle membranes and membrane-bound proteins must be recycled. The endocytic machinery that drives this recycling accumulates in the periactive zone (PAZ), a region of the synapse adjacent to active zon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b32503a30febef857a8ed3a98f14123
https://doi.org/10.1091/mbc.e22-08-0372
https://doi.org/10.1091/mbc.e22-08-0372
Autor:
Erica C. Dresselhaus, Kathryn P. Harris, Kate Koles, Matthew F. Pescosolido, Biljana Ermanoska, Mark Rozencwaig, Rebecca C. Soslowsky, Bryan A. Stewart, Avital A. Rodal
Exosomes are membrane-bound vesicles released by many cells including neurons, carrying cargoes involved in signaling and disease. It has been unclear whether exosomes promote intercellular signalingin vivoor serve primarily to dispose of unwanted ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd15d8842d6be707095506397de01cf
https://doi.org/10.1101/2023.04.22.537920
https://doi.org/10.1101/2023.04.22.537920
Autor:
Biljana Ermanoska, Bob Asselbergh, Laura Morant, Maria-Luise Petrovic-Erfurth, Seyyedmohsen Hosseinibarkooie, Ricardo Leitão-Gonçalves, Leonardo Almeida-Souza, Sven Bervoets, Litao Sun, LaTasha Lee, Derek Atkinson, Akram Khanghahi, Ivaylo Tournev, Patrick Callaerts, Patrik Verstreken, Xiang-Lei Yang, Brunhilde Wirth, Avital A. Rodal, Vincent Timmerman, Bruce L. Goode, Tanja A. Godenschwege, Albena Jordanova
Publikováno v:
Nature communications
Dominant mutations in tyrosyl-tRNA synthetase (YARS1) and six other tRNA ligases cause Charcot-Marie-Tooth peripheral neuropathy (CMT). Loss of aminoacylation is not required for their pathogenicity, suggesting a gain-of-function disease mechanism. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bea8833c474ce941d469fcf536b348
https://doi.org/10.1038/s41467-023-35908-3
https://doi.org/10.1038/s41467-023-35908-3
Autor:
Charlotte F. Kelley, Emily M. Messelaar, Tania L. Eskin, Shiyu Wang, Kangkang Song, Kalanit Vishnia, Agata N. Becalska, Oleg Shupliakov, Michael F. Hagan, Dganit Danino, Olga S. Sokolova, Daniela Nicastro, Avital A. Rodal
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2597-2609 (2015)
F-BAR domain proteins regulate and sense membrane curvature by interacting with negatively charged phospholipids and assembling into higher-order scaffolds. However, regulatory mechanisms controlling these interactions are poorly understood. Here, we
Externí odkaz:
https://doaj.org/article/f4e783064bf04fd8931e25a2b98a39f3
1.AbstractFollowing exocytosis at active zones, synaptic vesicle membranes and membrane-bound proteins must be recycled. The endocytic machinery that drives this recycling accumulates in the periactive zone (PAZ), a region of the synapse adjacent to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48940d235dd9dd4e55a07e08f5d001cd
https://doi.org/10.1101/2022.06.16.496425
https://doi.org/10.1101/2022.06.16.496425
Autor:
Cassandra R. Blanchette, Amy L. Scalera, Kathryn P. Harris, Zechuan Zhao, Erica C. Dresselhaus, Kate Koles, Anna Yeh, Julia K. Apiki, Bryan A. Stewart, Avital A. Rodal
Publikováno v:
Journal of Cell Biology. 221
Neuronal extracellular vesicles (EVs) are locally released from presynaptic terminals, carrying cargoes critical for intercellular signaling and disease. EVs are derived from endosomes, but it is unknown how these cargoes are directed to the EV pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3052dd816a104c5375865bfb16317002
https://doi.org/10.1083/jcb.202112094
https://doi.org/10.1083/jcb.202112094
Publikováno v:
Neuron. 110(5)
In this issue of Neuron, Yang et al. show that autophagy machinery is tightly coupled to neuronal activity via endocytic cycling of the transmembrane protein ATG-9 at presynaptic terminals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86341a02fead943012e3b93b0630162b
https://pubmed.ncbi.nlm.nih.gov/35065714
https://pubmed.ncbi.nlm.nih.gov/35065714
Publikováno v:
Curr Opin Neurobiol
Neurons release membrane-bound extracellular vesicles (EVs) carrying proteins, nucleic acids, and other cargoes to mediate neuronal development, plasticity, inflammation, regeneration, and degeneration. Functional studies and therapeutic intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90415f252c0c2403f670a5a60b16c93f
https://doi.org/10.1016/j.conb.2020.03.013
https://doi.org/10.1016/j.conb.2020.03.013