Výsledky vyhledávání - "Avisa Maleki"

Akademický článek

Beyond the state of the art of reverse vaccinology: predicting vaccine efficacy with the universal immune system simulator for influenza

Autor: Giulia Russo, Elena Crispino, Avisa Maleki, Valentina Di Salvatore, Filippo Stanco, Francesco Pappalardo

Publikováno v: BMC Bioinformatics, Vol 24, Iss 1, Pp 1-22 (2023)

Abstract When it was first introduced in 2000, reverse vaccinology was defined as an in silico approach that begins with the pathogen's genomic sequence. It concludes with a list of potential proteins with a possible, but not necessarily, list of pep

Externí odkaz: https://doaj.org/article/7ff803bd435f487487fae84ec60b93ad

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Akademický článek

Moving forward through the in silico modeling of multiple sclerosis: Treatment layer implementation and validation

Autor: Avisa Maleki, Elena Crispino, Serena Anna Italia, Valentina Di Salvatore, Maria Assunta Chiacchio, Fianne Sips, Roberta Bursi, Giulia Russo, Davide Maimone, Francesco Pappalardo

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3081-3090 (2023)

Multiple sclerosis is an autoimmune inflammatory disease that affects the central nervous system through chronic demyelination and loss of oligodendrocytes. Since the relapsing-remitting form is the most prevalent, relapse-reducing therapies are a pr

Externí odkaz: https://doaj.org/article/ba08fa880ed64faeb056e96e943b35f2

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Akademický článek

Computational identification of differentially-expressed genes as suggested novel COVID-19 biomarkers: A bioinformatics analysis of expression profiles

Autor: Valentina Di Salvatore, Elena Crispino, Avisa Maleki, Giulia Nicotra, Giulia Russo, Francesco Pappalardo

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3339-3354 (2023)

COVID-19 was declared a pandemic in March 2020, and since then, it has not stopped spreading like wildfire in almost every corner of the world, despite the many efforts made to stem its spread. SARS-CoV-2 has one of the biggest genomes among RNA viru

Externí odkaz: https://doaj.org/article/abac4ffc0adf487d95956180327fba42

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Akademický článek

In silico design of recombinant multi-epitope vaccine against influenza A virus

Autor: Avisa Maleki, Giulia Russo, Giuseppe Alessandro Parasiliti Palumbo, Francesco Pappalardo

Publikováno v: BMC Bioinformatics, Vol 22, Iss S14, Pp 1-19 (2022)

Abstract Background Influenza A virus is one of the leading causes of annual mortality. The emerging of novel escape variants of the influenza A virus is still a considerable challenge in the annual process of vaccine production. The evolution of vac

Externí odkaz: https://doaj.org/article/fde0f50baeb849c89db66de89119536d

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Akademický článek

Determining Difference in Evolutionary Variation of Bacterial RecA proteins vs 16SrRNA Genes by using 16s_Toxonomy Tree

Autor: Avisa Maleki, Hossein Fahimi, Mohammad Taghizadeh

Publikováno v: Iranian Journal of Medical Microbiology, Vol 13, Iss 1, Pp 32-43 (2019)

Background and Aims: The rate of variation in various genes of a bacterial species is different during evolution. Therefore, in systematic bacterial studies many researchers compare the phylogenetic tree of a particular gene to the standard tree of a

Externí odkaz: https://doaj.org/article/4f8384648fb144bda30b1fb781cfa5a2

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