Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Avineesh Singh"'
Autor:
Vijay K. Patel, Avineesh Singh, Deepak K. Jain, Preeti Patel, Ravichandran Veerasamy, Prabodh C. Sharma, Harish Rajak
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 3, Iss 2, Pp 71-78 (2017)
The structure and ligand based synergistic approach is being applied to design ligands more correctly. The present report discloses the combination of structure and ligand based tactics i.e., molecular docking, energetic based pharmacophore, pharmaco
Externí odkaz:
https://doaj.org/article/0313bdd947b94a9a8eb9e552612338c5
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 5, Pp 337-343 (2015)
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human
Externí odkaz:
https://doaj.org/article/133e001d55fa4464a30f792a1c1360cf
Publikováno v:
Current Computer-Aided Drug Design. 15:145-166
Background: Overexpression of Histone deacetylase 1 (HDAC1) is responsible for carcinogenesis by promoting epigenetic silence of tumour suppressor genes. Thus, HDAC1 inhibitors have emerged as the potential therapeutic leads against multiple human ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dead4c4059f3a0695ce9b7f948832ec
https://doi.org/10.2174/1573409914666180502113135
https://doi.org/10.2174/1573409914666180502113135
Autor:
Deepak Kumar Jain, Harish Rajak, Preeti Patel, Avineesh Singh, Vijay K. Patel, Jageshwar, Mehnaz Kamal
Publikováno v:
Current Cancer Drug Targets. 18:720-736
Histone deacetylase inhibitors (HDACi) have been demonstrated as an emerging class of anticancer drugs involved in regulation of gene expression and chromatin remodeling thus indicating valid targets for different types of cancer therapeutics. The pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a74f0178e26dddcbb140e07ac0bab9
https://doi.org/10.2174/1568009617666170630124643
https://doi.org/10.2174/1568009617666170630124643
Autor:
Deepak Kumar Jain, Prabodh Chander Sharma, Harish Rajak, Preeti Patel, Vijay K. Patel, Avineesh Singh, Ravichandran Veerasamy
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 3, Iss 2, Pp 71-78 (2017)
The structure and ligand based synergistic approach is being applied to design ligands more correctly. The present report discloses the combination of structure and ligand based tactics i.e., molecular docking, energetic based pharmacophore, pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f047db0234795f57756448d7b63343
http://www.sciencedirect.com/science/article/pii/S2314724516300371
http://www.sciencedirect.com/science/article/pii/S2314724516300371
Publikováno v:
Journal of Molecular Structure. 1240:130590
Pyrrole is a biologically active scaffold, which itself possess noticeable anticancer activity against several types of cancer specially leukemia, lymphoma, and myelofibrosis. SAHA and its synthetic analogs has demonstrated potent antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3af4c22af89299a78f1a9a9fb60196b
https://doi.org/10.1016/j.molstruc.2021.130590
https://doi.org/10.1016/j.molstruc.2021.130590
Autor:
Ravichandran Veerasamy, Vijay K. Patel, Deepak Kumar Jain, Harish Rajak, Anshuman Dixit, Kamlesh Raghuwanshi, Avineesh Singh
Publikováno v:
Pharmaceutical Chemistry Journal. 51:366-374
Histone deacetylase (HDAC) is a promising target for cancer treatment. HDAC inhibitors consist of three pharmacophoric features: an aromatic cap group, zinc binding group (ZBG), and a linker chain connecting cap group to ZBG. Herein, we report on (i)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c200bb6167bc0dde93fa8b98b9c2c87f
https://doi.org/10.1007/s11094-017-1616-1
https://doi.org/10.1007/s11094-017-1616-1
Publikováno v:
Dhaka University Journal of Pharmaceutical Sciences. 16:21-28
A simple, inexpensive, rapid and novel stability indicating isocratic HPLC method has been developed and validated for quantitative analysis of ertapenem sodium in the bulk drug and in pharmaceutical dosage form. An isocratic separation of ertapenem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3e32b7ee76f20dae824a94fa56da74d
https://doi.org/10.3329/dujps.v16i1.33378
https://doi.org/10.3329/dujps.v16i1.33378
Autor:
Vijay K. Patel, Navneet Aggarwal, Deepak Kumar Jain, Ravichandran Veerasamy, Avineesh Singh, Harish Rajak
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 17:30-50
Anticonvulsant refers to a group of pharmaceuticals used in the treatment of epileptic seizures. The use of current antiepileptic drugs has been questioned due to the non-selectivity of the drugs and the undesirable side effects produced by them. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863ce2590edfbab9c00d7d3780da066b
https://doi.org/10.2174/1871524916666160411143941
https://doi.org/10.2174/1871524916666160411143941
Autor:
Harish Rajak, Ravichandran Veerasamy, Kavibhushan Singh Chouhan, Rajesh Singh Pawar, P. K. Singour, Deepak Kumar Jain, Vijay K. Patel, Avineesh Singh
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17b39c6a705f925336a4ee44e51cd57
https://doi.org/10.2174/1570180811666141010000110
https://doi.org/10.2174/1570180811666141010000110