Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Avinash Khandagale"'
Autor:
Avinash Khandagale, Padraic Corcoran, Maryam Nikpour, Anders Isaksson, Gerhard Wikström, Agneta Siegbahn, Christina Christersson
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11964 (2022)
Pulmonary arterial hypertension (PAH) is characterized by a progressive elevation of pulmonary pressure leading to right ventricular dysfunction and is associated with a poor prognosis. Patients with PAH have increased numbers of circulating extracel
Externí odkaz:
https://doaj.org/article/804ef9f79bd54ccf885e263c1584325c
Autor:
Avinash Khandagale, Jens M. Kittner, Amrit Mann, Stefanie Ascher, Bettina Kollar, Christoph Reinhardt
Publikováno v:
Biology Open, Vol 7, Iss 7 (2018)
Patients with inflammatory bowel disease (IBD) are susceptible to thromboembolism. Interestingly, IBD occurs less frequently in patients with inherited bleeding disorders. Therefore, we analyzed whether F9-deficiency is protective against the onset o
Externí odkaz:
https://doaj.org/article/2326bf87778d4db8a02208be3f7b7283
Autor:
Klytaimnistra Kiouptsi, Alexandra Grill, Amrit Mann, Mareike Döhrmann, Maren Lillich, Sven Jäckel, Frano Malinarich, Henning Formes, Davit Manukyan, Saravanan Subramaniam, Avinash Khandagale, Cornelia Karwot, Serge C Thal, Markus Bosmann, Inge Scharrer, Kerstin Jurk, Christoph Reinhardt
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183590 (2017)
Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVIII) in plasma. It has been reported that the infusion of FVIII concentrate in haemophilia A patients results in lowered VWF plasma levels. However, the impact
Externí odkaz:
https://doaj.org/article/904641af907b4c6ead4f9012e1402f47
Autor:
Christersson, Avinash Khandagale, Padraic Corcoran, Maryam Nikpour, Anders Isaksson, Gerhard Wikström, Agneta Siegbahn, Christina
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11964
Pulmonary arterial hypertension (PAH) is characterized by a progressive elevation of pulmonary pressure leading to right ventricular dysfunction and is associated with a poor prognosis. Patients with PAH have increased numbers of circulating extracel
Autor:
Miriam Entesarian, Magnus Nordenskjöld, Avinash Khandagale, Daniel Nilsson, Krzysztof Kałwak, Teresa Holmlund, Bengt Fadeel, Maja Klaudel-Dreszler, Jan-Inge Henter, Göran Carlsson
Publikováno v:
British Journal of Haematology
Summary Severe congenital neutropenia (SCN) of autosomal recessive inheritance, also known as Kostmann disease, is characterised by a lack of neutrophils and a propensity for life‐threatening infections. Using whole‐exome sequencing, we identifie
Autor:
Ganna Shevchenko, Erik Björklund, Mikael Åberg, Avinash Khandagale, Gerhard Wikström, Christina Christersson, Agneta Siegbahn, Sara Bergström Lind
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:2293-2309
Objective: Extracellular vesicles (EVs) have the potential to act as intercellular communicators. The aims were to characterize circulating EVs in patients with pulmonary arterial hypertension (PAH) and to explore whether these EVs contribute to endo
Publikováno v:
Circulation. 144
Introduction: Adverse ventricular remodeling may occur after myocardial infarction (MI) and is associated with an increased risk of heart failure and death. Extracellular vesicles (EVs) derived exogenously from pluripotent stem cells exert cardioprot
Publikováno v:
European Heart Journal. 40
Background Pulmonary Arterial Hypertension (PAH) is a progressive condition with remodeling of precapillary arteries. Cytokines involved in angiogenesis have been found elevated in PAH but the role of proangiogenic factors and their regulation is far
Publikováno v:
Frontiers in Bioscience. 23:752-766
The commensal gut microbiota is an environmental factor that exerts manifold effects on host physiology. One obvious trait is the impact of this densely colonized ecosystem on small intestinal mucosal vascularization. At present, the microbiota-trigg
Autor:
Göran Carlsson, Beatrice Lazzaretto, Mikael Sundin, Ute Römling, Avinash Khandagale, Bengt Fadeel, Sulman Shafeeq
Publikováno v:
Journal of Leukocyte Biology
Mutations in the gene JAGN1 were recently discovered in patients with severe congenital neutropenia (SCN). Neutrophils release neutrophil extracellular traps (NETs) consisting of decondensed chromatin decorated with various granular proteins such as