Výsledky vyhledávání - "Avinash C Tripathi"

Akademický článek

Isolation and characterization of quinine from Polygonatum verticillatum: A new marker approach to identify substitution and adulteration

Autor: Jaswinder Kaur Virk, Sanjiv Kumar, Ranjit Singh, Avinash C Tripathi, Shailendra K Saraf, Vikas Gupta, Parveen Bansal

Publikováno v: Journal of Advanced Pharmaceutical Technology & Research, Vol 7, Iss 4, Pp 153-158 (2016)

Polygonatum verticillatum (Mahameda) is an important ingredient of Ashtawarga and Ayurvedic formulations. Nowadays, it comes under the category of endangered plants due to large scale and indiscriminate collection of wild material. To overcome the sc

Externí odkaz: https://doaj.org/article/72c9d71ffdd84196b09bb4ccd751a775

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Ligand and Structure-Based Hybrid Screening for Anti-Parkinson Agents and their Pharmacological Evaluation

Autor: Pankaj Kumar Sonar, Avinash C. Tripathi, Mudita Mishra, Shailendra K. Saraf, Santosh Kumar Verma

Publikováno v: INTERNATIONAL JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (IJPER). 2:30-38

The behavioral and biochemical antiparkinson effect of 7-hydroxyflavone (7-HF) was evaluated by using virtual screening with an e-pharmacophore and shape-based screening approach, and the compound was screened by using the Sigma Aldrich compound libr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25b47a12f159ea09e4b773291fc164c8
https://doi.org/10.37021/ijper.v2i2.1

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PHD-2 activation: a novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype

Autor: Avinash C. Tripathi, Pushpraj S Gupta, Gaurav Kaithwas, Abdulaziz S. Saeedan, Manjari Singh, Subhadeep Roy, Nazam Ansari, Shailendra K. Saraf, Uma Devi

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 392:1239-1256

Estrogen receptor-positive mammary gland carcinoma and its involvement in regulation of overexpressed hypoxia-inducible factor-1α and fatty acid synthase level in hypoxia influenced cancer cells are the present molecular crosstalk of this entire stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8275b63bf1900d72fa38351e4d9166
https://doi.org/10.1007/s00210-019-01658-7

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Derivatives of 4,5-dihydro (1H) pyrazoles as possible MAO-A inhibitors in depression and anxiety disorders: synthesis, biological evaluation and molecular modeling studies

Autor: Avinash C. Tripathi, Sarvesh Paliwal, Shailendra K. Saraf, Savita Upadhyay

Publikováno v: Medicinal Chemistry Research. 27:1485-1503

A series of 1,3,5-trisubstituted-2-pyrazoline derivatives (3a–3t) were synthesized in appreciable yields by substituting N1 position of 2-pyrazoline nucleus with 4-nitrobenzenesulfonylchloride using conventional and microwave assisted synthetic app

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35766c89f63a1a5a3032ef0270e5f8fc
https://doi.org/10.1007/s00044-018-2167-z

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Privileged scaffolds as MAO inhibitors: Retrospect and prospects

Autor: Savita Upadhyay, Sarvesh Paliwal, Avinash C. Tripathi, Shailendra K. Saraf

Publikováno v: European Journal of Medicinal Chemistry. 145:445-497

This review aims to be a comprehensive, authoritative, critical, and readable review of general interest to the medicinal chemistry community because it focuses on the pharmacological, chemical, structural and computational aspects of diverse chemica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abca0ca9dc69532c3678166411a77447
https://doi.org/10.1016/j.ejmech.2018.01.003

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Synthesis and Development of Some Quinolone/Fluoroquinolone- Latentiated Drug Polypeptide Systems and Their Antimicrobial Evaluation

Autor: Shailendra K. Saraf, Manju Rawat, Avinash C. Tripathi

Publikováno v: International Journal of ChemTech Research. 11:298-307

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e454157fbf5967ff8c6cb9a4fb5d5fa
https://doi.org/10.20902/ijctr.2018.111037

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Facile One-Pot Synthesis Methodology for Nitrogen-Containing Heterocyclic Derivatives of 3,5-Disubstituted 4,5-Dihydro-1H-Pyrazole, Their Biological Evaluation and Molecular Docking Studies

Autor: Savita Upadhyay, Sarvesh Paliwal, Avinash C. Tripathi, Shailendra K. Saraf

Publikováno v: Pharmaceutical Chemistry Journal. 51:564-575

A series of 2-pyrazoline derivatives (PS-1 to PS-16) were synthesized by reacting different aromatic/heteroaromatic aldehydes and ketones, in a two-step reaction through Claisen – Schmidt condensation, followed by cyclization of the resulting chalc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52d40a1ecd455b98f95c5736b41a0220
https://doi.org/10.1007/s11094-017-1655-7

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Design and microwave facilitated green synthesis of 2-[4-(3-carboxymethyl, methoxy carbonylmethyl-2,4-dioxo and 4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-2 and 3-methyl propionic acid ethyl ester derivatives: a novel structural class of antidyslipidemic agents

Autor: Avinash C. Tripathi, Ashok Kumar Singh, Shailendra K. Saraf, Viney Chawla, Aseem Tewari

Publikováno v: Medicinal Chemistry Research. 26:1535-1549

An interesting hybrid molecular framework comprising of benzylidenethiazolidin-4-one, chalcone and fibrate was designed and synthesized (BRF1–12) in order to develop safe and efficacious compounds for the treatment of dyslipidemia, and related comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e8ecaf594095cad0359f019d17de3bd
https://doi.org/10.1007/s00044-017-1875-0

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Facile synthesis, molecular docking and toxicity studies of 4-Phenyl-3-phenylamino-4H-[1,2,4]thiadiazol-5-one analogs as GABAA receptor agonists

Autor: Pankaj Kumar Sonar, Shailendra K. Saraf, Kirti Diwakar, Mudita Mishra, Avinash C. Tripathi

Publikováno v: Medicinal Chemistry Research. 25:2631-2642

A series of 4-Phenyl-3-phenylamino-4H-[1,2,4]thiadiazol-5-one derivatives was synthesized by a simple method and their structures were established by physical and spectroscopic methods like infrared, mass and nuclear magnetic resonance spectroscopy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9b39e1f7eba245a21e51f1a3daefb1b
https://doi.org/10.1007/s00044-016-1697-5

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Structural Insights into the Molecular Design of HER2 Inhibitors

Autor: Avinash C. Tripathi, Pankaj Kumar Sonar, Shailendra K. Saraf, Ravindranath Rathore

Publikováno v: Open Pharmaceutical Sciences Journal. 3:164-181

Background: The present study was aimed at designing some potential candidates as HER2 inhibitors used in breast cancer. Methods: An energy optimized pharmacophore (E-pharmacophore) model was developed and used to screen the molecular databases (such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a9b39f0faffb6b3e2dccf842b6c0e6b
https://doi.org/10.2174/1874844901603010164

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