Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Avijit Chakrabartty"'
Autor:
Anna Weichert, Anna S. Besemer, Martina Liebl, Nadja Hellmann, Ingrid Koziollek-Drechsler, Philbert Ip, Heinz Decker, Janice Robertson, Avijit Chakrabartty, Christian Behl, Albrecht M. Clement
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 479-488 (2014)
Mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) are responsible for a subset of amyotrophic lateral sclerosis cases presumably by the acquisition of as yet unknown toxic properties. Additional overexpression of wild-type SOD1 in muta
Externí odkaz:
https://doaj.org/article/5a7ad8d4cb184b3eb7720154d235762b
Publikováno v:
PLoS Biology, Vol 14, Iss 4, p e1002447 (2016)
Externí odkaz:
https://doaj.org/article/2a48ca24ff584ca2918c10068688329d
Autor:
Kevin C Hadley, Rishi Rakhit, Hongbo Guo, Yulong Sun, James EN Jonkman, Joanne McLaurin, Lili-Naz Hazrati, Andrew Emili, Avijit Chakrabartty
Publikováno v:
eLife, Vol 4 (2015)
Spatially targeted optical microproteomics (STOMP) is a novel proteomics technique for interrogating micron-scale regions of interest (ROIs) in mammalian tissue, with no requirement for genetic manipulation. Methanol or formalin-fixed specimens are s
Externí odkaz:
https://doaj.org/article/4d756f0870714a259fed41cd7dfb1d57
N-terminal helix-cap in α-helix 2 modulates β-state misfolding in rabbit and hamster prion proteins.
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63047 (2013)
Susceptibility of a particular species to prion disease is affected by small differences in the sequence of PrP and correlates with the propensity of its PrP to assume the β-state. A helix-cap motif in the β2-α2-loop of native α-helical rabbit Pr
Externí odkaz:
https://doaj.org/article/f2666b05672e4a3d8eb7289d6c7c9200
Autor:
David A. Bateman, Avijit Chakrabartty
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
The amyloid peptides, Aβ40 and Aβ42, are generated through endoproteolytic cleavage of the amyloid precursor protein. Here we have developed a model to investigate the interaction of living cells with various forms of aggregated Aβ40/42. After inc
Externí odkaz:
https://doaj.org/article/12139e56fd804e44999581c20c653419
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Externí odkaz:
https://doaj.org/article/42c1da0fed8a40dfa60f618aec5a57cd
Autor:
Debashree Chowdhury, Arvind Agarwal, Avijit Chakrabartty, S.S. Iyer, K.. M. Gopal, P. S. Saravanamurthy, Shantanu Purohit, P. Mishra
Publikováno v:
Public Health. 164:49-56
Objectives To explore the vulnerabilities and risks of HIV infection among female migrants compared with male migrants in the Thane district of Maharashtra, India. Study design This is a cross-sectional epidemiological study. Methods Data from 35,841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0934c917389278f6a330506b9ffa363
https://doi.org/10.1016/j.puhe.2018.07.019
https://doi.org/10.1016/j.puhe.2018.07.019
Publikováno v:
Clinical Science. 131:395-409
Transthyretin (TTR) amyloidosis (ATTR amyloidosis) is an underdiagnosed and important type of cardiomyopathy and/or polyneuropathy that requires increased awareness within the medical community. Raising awareness among clinicians about this type of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6165291a1dcc6db0b0b908a2bedf0cc0
https://doi.org/10.1042/cs20160413
https://doi.org/10.1042/cs20160413
Autor:
Yulong Sun, Avijit Chakrabartty
Publikováno v:
Biochemistry. 56:809-823
TDP-43 is a dimeric nuclear protein that plays a central role in RNA metabolism. In recent years, this protein has become a focal point of research in the amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) disease spectrum, as pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea82c0c0c8ac33f618137f410ecb91d
https://doi.org/10.1021/acs.biochem.6b01088
https://doi.org/10.1021/acs.biochem.6b01088
Publikováno v:
Journal of Visualized Experiments.
Immunofluorescence is a common method used to visualize subcellular compartments and to determine the localization of specific proteins within a tissue sample. A great hindrance to the acquisition of high quality immunofluorescence images is endogeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812662fa7c279e6e49da0c65dad4f9a9
https://doi.org/10.3791/56188-v
https://doi.org/10.3791/56188-v