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Autor:
Andreas Linkermann, Stephen Henderson, Helena Draberova, Katarzyna Wojdyla, Diego de Miguel, Avigayil Chalk, Elodie Lafont, Anne von Mässenhausen, Sebastian Kupka, Eva Rieser, Amandeep Bhamra, Matthias Reichert, Henning Walczak, Silvia Surinova, Peter Draber
Publikováno v:
Nature cell biology
The linear-ubiquitin chain assembly complex (LUBAC) modulates signalling via various immune receptors. In tumour necrosis factor (TNF) signalling, linear (also known as M1) ubiquitin enables full gene activation and prevents cell death. However, the