Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Avigail Baruch Leshem"'
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Biomolecular condensates are condensed intracellular phases that are formed by liquid-liquid phase separation (LLPS) of proteins, either in the absence or presence of nucleic acids. These condensed phases regulate various biochemical reactio
Externí odkaz:
https://doaj.org/article/503f54db13814324a8a646f1f94f2980
Autor:
Avigail Baruch Leshem, Sian Sloan-Dennison, Tlalit Massarano, Shavit Ben-David, Duncan Graham, Karen Faulds, Hugo E. Gottlieb, Jordan H. Chill, Ayala Lampel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The molecular mechanisms underlying the formation of biomolecular condensates have not been fully elucidated. Here the authors show that the LLPS propensity, dynamics, and encapsulation efficiency of designed peptide condensates can be tuned by subtl
Externí odkaz:
https://doaj.org/article/f00422fac195453c853a9e060b8a14fb
Publikováno v:
ACS Applied Materials & Interfaces. 14:20520-20527
Melanins are natural biopolymers that have remarkable properties including UV-protection, coloration, and antioxidant activity. Their biosynthesis is regulated both spatially and temporally and involves supramolecular templating and compartmentalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a3f28435993b3a3a6a2bd93b3cd772
https://doi.org/10.1021/acsami.1c21006
https://doi.org/10.1021/acsami.1c21006
Publikováno v:
Chem Catalysis. 1:908-922
Summary Amyloid fibrils are one of the hallmarks of Alzheimer's disease (AD), although a causative link between plaque-forming amyloid fibrils and AD pathology remains to be clarified. This study demonstrates, for the first time for a naturally occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0bd29b97e47c19aef4ba79ddf1d99c8
https://doi.org/10.1016/j.checat.2021.07.005
https://doi.org/10.1016/j.checat.2021.07.005
Autor:
Avigail Baruch Leshem, Sian Sloan-Dennison, Tlalit Massarano, Shavit Ben-David, Duncan Graham, Karen Faulds, Hugo E. Gottlieb, Jordan H. Chill, Ayala Lampel
Inspired by the role of intracellular liquid-liquid phase separation (LLPS) in formation of membraneless organelles, there is great interest in developing dynamic compartments formed by LLPS of intrinsically disordered proteins (IDPs) or short peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e48c3e2c6407fb1add91b05a166508
https://doi.org/10.26434/chemrxiv-2022-013k3
https://doi.org/10.26434/chemrxiv-2022-013k3
Autor:
Verena Wulf, Ella Bichachi, Adi Hendler‐Neumark, Tlalit Massarano, Avigail Baruch Leshem, Ayala Lampel, Gili Bisker
Publikováno v:
Advanced Functional Materials. 32:2270281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9beeabc627cfcaa80b75836a02d5f585
https://doi.org/10.1002/adfm.202270281
https://doi.org/10.1002/adfm.202270281
Autor:
Sachin K. Srivastava, Ibrahim Abdulhalim, Ariel Kushmaro, Hanna Rapaport, Avigail Baruch Leshem, Sivan Isaacs
Publikováno v:
Journal of Colloid and Interface Science. 530:328-337
Organophosphate compounds that are used as pesticides affect the nervous system by binding irreversibly to the active site of the enzyme acetylcholine esterase (AChE) and disrupting neuro-signaling nerve cells. In this study we characterized adsorpti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e68ffe64e02bdee358488104f5c93f0
https://doi.org/10.1016/j.jcis.2018.06.065
https://doi.org/10.1016/j.jcis.2018.06.065
Autor:
Corinne Chevallard, Michel Goldmann, Ariel Kushmaro, Hanna Rapaport, Avigail Baruch-Leshem, Frédéric Gobeaux, Jean Daillant, Philippe Fontaine, Patrick Guenoun
Publikováno v:
Colloids and Surfaces B: Biointerfaces
Colloids and Surfaces B: Biointerfaces, Elsevier, 2021, 203, pp.111751. ⟨10.1016/j.colsurfb.2021.111751⟩
Colloids and Surfaces B: Biointerfaces, 2021, 203, pp.111751. ⟨10.1016/j.colsurfb.2021.111751⟩
Colloids and Surfaces B: Biointerfaces, Elsevier, 2021, 203, pp.111751. ⟨10.1016/j.colsurfb.2021.111751⟩
Colloids and Surfaces B: Biointerfaces, 2021, 203, pp.111751. ⟨10.1016/j.colsurfb.2021.111751⟩
International audience; Amphiphilic peptides that induce catalysis are interesting alternatives to natural enzymes thanks to robustness of their synthesis and the ability to induce certain types of conformations by specific motifs of amino acid seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b797f7c781a6c262e0803bf473988737
https://doi.org/10.1016/j.colsurfb.2021.111751
https://doi.org/10.1016/j.colsurfb.2021.111751
Publikováno v:
Israel Journal of Chemistry. 55:661-670
Amphiphilic peptides can be designed to form ordered supramolecular structures at hydrophilic-hydrophobic interfaces. These systems rely on the ability of peptides to fold into certain secondary structures at interfaces. This review focuses on the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d999a2e7c344025b927d80da007746
https://doi.org/10.1002/ijch.201400172
https://doi.org/10.1002/ijch.201400172