Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Avi Swed"'
Autor:
Alaa Talhami, Avi Swed, Shmuel Hess, Oded Ovadia, Sarit Greenberg, Adi Schumacher-Klinger, David Rosenthal, Deborah E. Shalev, Mattan Hurevich, Philip Lazarovici, Amnon Hoffman, Chaim Gilon
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Painkillers are commonly used medications. Native peptide painkillers suffer from various pharmacological disadvantages, while small molecule painkillers like morphine are highly addictive. We present a general approach aimed to use backbone-cyclizat
Externí odkaz:
https://doaj.org/article/214c0a356de24363ad9340767112adf5
Publikováno v:
Molecular Pharmaceutics. 6:1883-1890
Tetraphenylphosphonium (TPP), a phosphonium cation, is a promising means for tumor imaging. A major contributor to the pharmacokinetics of phosphonium cations is the efflux transporter P-glycoprotein (P-gp). For this application it is important to as
Autor:
Salim Joubran, Laurence Briant-Longuet, Noam S. Freeman, Mattan Hurevich, Martine Bardy, Amnon Hoffman, Christian Devaux, Elena Britan-Rosich, Chaim Gilon, Avi Swed, Moshe Kotler, Shira Cohen
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2010, 18 (15), pp.5754-5761. ⟨10.1016/j.bmc.2010.04.053⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2010, 18 (15), pp.5754-5761. ⟨10.1016/j.bmc.2010.04.053⟩
International audience; Rational conversion of noncontinuous active regions of proteins into a small orally bioavailable molecule is crucial for the discovery of new drugs based on inhibition of protein-protein interactions. We developed a method tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509709cec96f1ac268e954364040c634
https://hal.archives-ouvertes.fr/hal-00505767
https://hal.archives-ouvertes.fr/hal-00505767
Autor:
Avi Faier, Dana Yarden, Efrat Halbfinger, Yael Gabinet, Deborah E. Shalev, Oded Ovadia, Shmuel Hess, Zhimin Xiang, Tair Lapidot, Avi Swed, Yaniv Linde, Chaim Gilon, Carrie Haskell-Luevano, Amnon Hoffman, Eli Safrai, Federico P. Portillo, Ilan Winkler
Publikováno v:
Journal of medicinal chemistry. 51(4)
The tetrapeptide sequence His-Phe-Arg-Trp, derived from melanocyte-stimulating hormone (alphaMSH) and its analogs, causes a decrease in food intake and elevates energy utilization upon binding to the melanocortin-4 receptor (MC4R). To utilize this se
Autor:
Shmuel Hess, Yaniv Linde, Oded Ovadia, Eli Safrai, Deborah E. Shalev, Avi Swed, Efrat Halbfinger, Tair Lapidot, Ilan Winkler, Yael Gabinet, Avi Faier, Dana Yarden, Zhimin Xiang, Federico P. Portillo, Carrie Haskell-Luevano, Chaim Gilon, Amnon Hoffman
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 4, p1026-1034, 9p